| Topology of outer membrane porins in pathogenic Neisseria spp P Van Der Ley, JE Heckels, M Virji, P Hoogerhout, JT Poolman Infection and immunity 59 (9), 2963-2971, 1991 | 383 | 1991 |
| Meningitis bacterium is viable without endotoxin L Steeghs, R den Hartog, A den Boer, B Zomer, P Roholl, P van der Ley Nature 392 (6675), 449-449, 1998 | 367 | 1998 |
| Outer membrane vesicles as platform vaccine technology L Van Der Pol, M Stork, P van der Ley Biotechnology journal 10 (11), 1689-1706, 2015 | 362 | 2015 |
| Modification of Lipid A Biosynthesis inNeisseria meningitidis lpxL Mutants: Influence on Lipopolysaccharide Structure, Toxicity, and Adjuvant Activity P Van Der Ley, L Steeghs, HJ Hamstra, J ten Hove, B Zomer, ... Infection and immunity 69 (10), 5981-5990, 2001 | 268 | 2001 |
| Production, characterization and control of a Neisseria meningitidis hexavalent class 1 outer membrane protein containing vesicle vaccine I Claassen, J Meylis, P van der Ley, C Peeters, H Brons, J Robert, ... Vaccine 14 (10), 1001-1008, 1996 | 221 | 1996 |
| The genetic basis of the phase variation repertoire of lipopolysaccharide immunotypes in Neisseria meningitidis MP Jennings, YN Srikhanta, ER Moxon, M Kramer, JT Poolman, ... Microbiology 145 (11), 3013-3021, 1999 | 206 | 1999 |
| Improved OMV vaccine against Neisseria meningitidis using genetically engineered strains and a detergent-free purification process B Van de Waterbeemd, M Streefland, P Van der Ley, B Zomer, ... Vaccine 28 (30), 4810-4816, 2010 | 198 | 2010 |
| Phase I clinical trial with a hexavalent PorA containing meningococcal outer membrane vesicle vaccine C Peeters, HC Rümke, LC Sundermann, EMR van Der Voort, ... Vaccine 14 (10), 1009-1015, 1996 | 197 | 1996 |
| A Lipopolysaccharide-Deficient Mutant of Neisseria meningitidis Elicits Attenuated Cytokine Release by Human Macrophages and Signals via Toll-like Receptor … AC Pridmore, DH Wyllie, F Abdillahi, L Steeghs, P van der Ley, SK Dower, ... The Journal of infectious diseases 183 (1), 89-96, 2001 | 190 | 2001 |
| A Neisserial autotransporter NalP modulating the processing of other autotransporters P Van Ulsen, L Van Alphen, J Ten Hove, F Fransen, P Van Der Ley, ... Molecular microbiology 50 (3), 1017-1030, 2003 | 181 | 2003 |
| Construction of Neisseria meningitidis strains carrying multiple chromosomal copies of the porA gene for use in the production of a multivalent outer membrane vesicle vaccine P Van Der Ley, J van der Biezen, JT Poolman Vaccine 13 (4), 401-407, 1995 | 170 | 1995 |
| Outer membrane composition of a lipopolysaccharide‐deficient Neisseria meningitidis mutant L Steeghs, H de Cock, E Evers, B Zomer, J Tommassen, P van der Ley The EMBO journal, 2001 | 165 | 2001 |
| The Omp85 protein of Neisseria meningitidis is required for lipid export to the outer membrane S Genevrois, L Steeghs, P Roholl, JJ Letesson, P van der Ley The EMBO journal, 2003 | 161 | 2003 |
| The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium–host interaction BJ Appelmelk, J Den Dunnen, NN Driessen, R Ummels, M Pak, J Nigou, ... Cellular microbiology 10 (4), 930-944, 2008 | 149 | 2008 |
| Construction of a multivalent meningococcal vaccine strain based on the class 1 outer membrane protein P Van Der Ley, JT Poolman Infection and immunity 60 (8), 3156-3161, 1992 | 140 | 1992 |
| Specificity of human bactericidal antibodies against PorA P1. 7, 16 induced with a hexavalent meningococcal outer membrane vesicle vaccine ER van der Voort, P Van der Ley, J Van der Biezen, S George, O Tunnela, ... Infection and immunity 64 (7), 2745-2751, 1996 | 137 | 1996 |
| Identification of a novel gene involved in pilin glycosylation in Neisseria meningitidis MP Jennings, M Virji, D Evans, V Foster, YN Srikhanta, L Steeghs, ... Molecular microbiology 29 (4), 975-984, 1998 | 131 | 1998 |
| Outer membrane vesicles obtained from Bordetella pertussis Tohama expressing the lipid A deacylase PagL as a novel acellular vaccine candidate CJA Asensio, ME Gaillard, G Moreno, D Bottero, E Zurita, M Rumbo, ... Vaccine 29 (8), 1649-1656, 2011 | 127 | 2011 |
| Shielding of Escherichia coli outer membrane proteins as receptors for bacteriophages and colicins by O-antigenic chains of lipopolysaccharide P Van der Ley, P De Graaff, J Tommassen Journal of bacteriology 168 (1), 449-451, 1986 | 110 | 1986 |
| Contributions of Neisseria meningitidis LPS and non-LPS to proinflammatory cytokine response T Sprong, N Stikkelbroeck, P van der Ley, L Steeghs, L van Alphen, ... Journal of leukocyte biology 70 (2), 283-288, 2001 | 109 | 2001 |
