Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer S Gao, S Chen, D Han, Z Wang, M Li, W Han, A Besschetnova, M Liu, ... Nature genetics 52 (10), 1011-1017, 2020 | 108 | 2020 |
Androgen receptor tumor suppressor function is mediated by recruitment of retinoblastoma protein S Gao, Y Gao, HH He, D Han, W Han, A Avery, JA Macoska, X Liu, ... Cell reports 17 (4), 966-976, 2016 | 106 | 2016 |
Reactivation of androgen receptor-regulated lipid biosynthesis drives the progression of castration-resistant prostate cancer W Han, S Gao, D Barrett, M Ahmed, D Han, JA Macoska, HH He, C Cai Oncogene 37 (6), 710-721, 2018 | 100 | 2018 |
LSD1-mediated epigenetic reprogramming drives CENPE expression and prostate cancer progression Y Liang, M Ahmed, H Guo, F Soares, JT Hua, S Gao, C Lu, C Poon, ... Cancer research 77 (20), 5479-5490, 2017 | 89 | 2017 |
TMPRSS2-ERG activates NO-cGMP signaling in prostate cancer cells F Zhou, S Gao, D Han, W Han, S Chen, S Patalano, JA Macoska, HH He, ... Oncogene 38 (22), 4397-4411, 2019 | 53 | 2019 |
ErbB2 signaling increases androgen receptor expression in abiraterone-resistant prostate cancer S Gao, H Ye, S Gerrin, H Wang, A Sharma, S Chen, A Patnaik, ... Clinical Cancer Research 22 (14), 3672-3682, 2016 | 53 | 2016 |
Forkhead domain mutations in FOXA1 drive prostate cancer progression S Gao, S Chen, D Han, D Barrett, W Han, M Ahmed, S Patalano, ... Cell research 29 (9), 770-772, 2019 | 42 | 2019 |
LSD1 Inhibition Disrupts Super-Enhancer–Driven Oncogenic Transcriptional Programs in Castration-Resistant Prostate Cancer M Li, M Liu, W Han, Z Wang, D Han, S Patalano, JA Macoska, SP Balk, ... Cancer research 83 (10), 1684-1698, 2023 | 35 | 2023 |
RB1 loss in castration-resistant prostate cancer confers vulnerability to LSD1 inhibition W Han, M Liu, D Han, M Li, AA Toure, Z Wang, A Besschetnova, ... Oncogene 41 (6), 852-864, 2022 | 33 | 2022 |
ZBTB7A mediates the transcriptional repression activity of the androgen receptor in prostate cancer D Han, S Chen, W Han, S Gao, JN Owiredu, M Li, SP Balk, HH He, C Cai Cancer research 79 (20), 5260-5271, 2019 | 31 | 2019 |
Exploiting the tumor-suppressive activity of the androgen receptor by CDK4/6 inhibition in castration-resistant prostate cancer W Han, M Liu, D Han, AA Toure, M Li, A Besschetnova, Z Wang, ... Molecular Therapy 30 (4), 1628-1644, 2022 | 28 | 2022 |
LSD1 activates PI3K/AKT signaling through regulating p85 expression in prostate cancer cells Z Wang, S Gao, D Han, W Han, M Li, C Cai Frontiers in Oncology 9, 721, 2019 | 19 | 2019 |
A novel nonsense mutation in androgen receptor confers resistance to CYP17 inhibitor treatment in prostate cancer D Han, S Gao, K Valencia, J Owiredu, W Han, E de Waal, JA Macoska, ... Oncotarget 8 (4), 6796, 2016 | 13 | 2016 |
Androgen receptor splice variants drive castration-resistant prostate cancer metastasis by activating distinct transcriptional programs D Han, M Labaf, Y Zhao, J Owiredu, S Zhang, K Patel, K Venkataramani, ... The Journal of Clinical Investigation 134 (11), 2024 | 9 | 2024 |
Demethylation of EHMT1/GLP protein reprograms its transcriptional activity and promotes prostate cancer progression A Besschetnova, W Han, M Liu, Y Gao, M Li, Z Wang, M Labaf, S Patalano, ... Cancer Research Communications 3 (8), 1716-1730, 2023 | 3 | 2023 |