עקוב אחר
Dr. Marcel J.J. Blommers
Dr. Marcel J.J. Blommers
Saverna Therapeutics
כתובת אימייל מאומתת בדומיין saverna.com - דף הבית
כותרת
צוטט על ידי
צוטט על ידי
שנה
SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice
J Palacino, SE Swalley, C Song, AK Cheung, L Shu, X Zhang, ...
Nature chemical biology 11 (7), 511-517, 2015
4492015
Discovery of potent antagonists of the interaction between human double minute 2 and tumor suppressor p53
C Garcia-Echeverria, P Chene, MJJ Blommers, P Furet
Journal of medicinal chemistry 43 (17), 3205-3208, 2000
3312000
A new class of HIV-1 Tat antagonist acting through Tat− TAR inhibition
F Hamy, V Brondani, A Flörsheimer, W Stark, MJJ Blommers, T Klimkait
Biochemistry 37 (15), 5086-5095, 1998
2051998
The INPHARMA method: protein-mediated interligand NOEs for pharmacophore mapping
VM Sánchez-Pedregal, M Reese, J Meiler, MJJ Blommers, C Griesinger, ...
Angewandte Chemie-International Edition 44 (27), 4172-4174, 2005
2042005
Effects of base sequence on the loop folding in DNA hairpins
MJJ Blommers, J Walters, CAG Haasnoot, JMA Aelen, GA Van der Marel, ...
Biochemistry 28 (18), 7491-7498, 1989
1631989
Characterization of the mechanism of action of the pan class I PI3K inhibitor NVP-BKM120 across a broad range of concentrations
SM Brachmann, J Kleylein-Sohn, S Gaulis, A Kauffmann, MJJ Blommers, ...
Molecular cancer therapeutics 11 (8), 1747-1757, 2012
1442012
The High‐Resolution Solution Structure of Epothilone A Bound to Tubulin: An Understanding of the Structure–Activity Relationships for a Powerful Class of Antitumor Agents
T Carlomagno, MJJ Blommers, J Meiler, W Jahnke, T Schupp, F Petersen, ...
Angewandte Chemie 115 (22), 2615-2619, 2003
1292003
The four terminal components of the complement system AreC-mannosylated on multiple tryptophan residues
J Hofsteenge, M Blommers, D Hess, A Furmanek, O Miroshnichenko
Journal of Biological Chemistry 274 (46), 32786-32794, 1999
1271999
Creating RNA bulges: cleavage of RNA in RNA/DNA duplexes by metal ion catalysis
D Hüsken, G Goodall, MJJ Blommers, W Jahnke, J Hall, R Häner, ...
Biochemistry 35 (51), 16591-16600, 1996
1171996
The three‐dimensional structure of a DNA hairpin in solution: Two‐dimensional NMR studies and structural analysis of d (ATCCTATTTATAGGAT)
MJJ Blommers, FJM Van De Ven, GA Van Der Marel, JH Van Boom, ...
European journal of biochemistry 201 (1), 33-51, 1991
1121991
L-DNAs as potenital antimessenger oligonucleotides: a reassessment
A Garbesi, ML Capobinanco, FP Colonna, L Tondelli, F Arcamone, ...
Nucleic acids research 21 (18), 4159-4165, 1993
1081993
Crystal structure of human estrogen-related receptor α in complex with a synthetic inverse agonist reveals its novel molecular mechanism
J Kallen, R Lattmann, R Beerli, A Blechschmidt, MJJ Blommers, M Geiser, ...
Journal of Biological Chemistry 282 (32), 23231-23239, 2007
1052007
Structural basis of the activity of the microtubule‐stabilizing agent epothilone a studied by NMR spectroscopy in solution
M Reese, VM Sánchez‐Pedregal, K Kubicek, J Meiler, MJJ Blommers, ...
Angewandte Chemie International Edition 46 (11), 1864-1868, 2007
1052007
Recombinant human interleukin-12 is the second example of a C-mannosylated protein
MA Doucey, D Hess, MJJ Blommers, J Hofsteenge
Glycobiology 9 (5), 435-441, 1999
1051999
Effects of the Introduction of L-Nucleotides into DNA. Solution Structure of the Heterochiral Duplex d (GCG-(L) TGCG). cntdot. d (CGCACGC) Studied by NMR Spectroscopy
MJJ Blommers, L Tondelli, A Garbesi
Biochemistry 33 (25), 7886-7896, 1994
1011994
Conformational analysis of a dinucleotide photodimer with the aid of the genetic algorithm
MJJ Blommers, CB Lucasius, G Kateman, R Kaptein
Biopolymers: Original Research on Biomolecules 32 (1), 45-52, 1992
1011992
Lipid− protein nanodiscs as reference medium in detergent screening for high-resolution NMR studies of integral membrane proteins
ZO Shenkarev, EN Lyukmanova, AS Paramonov, LN Shingarova, ...
Journal of the American Chemical Society 132 (16), 5628-5629, 2010
992010
Dual recognition of double-stranded DNA by 2 ‘-aminoethoxy-modified oligonucleotides: the solution structure of an intramolecular triplex obtained by NMR spectroscopy
MJJ Blommers, F Natt, W Jahnke, B Cuenoud
Biochemistry 37 (51), 17714-17725, 1998
951998
Second-site NMR screening and linker design
W Jahnke, A Florsheimer, MJJ Blommers, C Paris, J Heim, CM Nalin, ...
Current Topics in Medicinal Chemistry 3 (1), 69-80, 2003
832003
An approach to the structure determination of nucleic acid analogues hybridized to RNA. NMR studies of a duplex between 2′-OMe RNA and an oligonucleotide containing a single …
MJJ Blommers, U Pieles, A Mesmaeker
Nucleic acids research 22 (20), 4187-4194, 1994
821994
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מאמרים 1–20