SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice J Palacino, SE Swalley, C Song, AK Cheung, L Shu, X Zhang, ... Nature chemical biology 11 (7), 511-517, 2015 | 449 | 2015 |
Discovery of potent antagonists of the interaction between human double minute 2 and tumor suppressor p53 C Garcia-Echeverria, P Chene, MJJ Blommers, P Furet Journal of medicinal chemistry 43 (17), 3205-3208, 2000 | 331 | 2000 |
A new class of HIV-1 Tat antagonist acting through Tat− TAR inhibition F Hamy, V Brondani, A Flörsheimer, W Stark, MJJ Blommers, T Klimkait Biochemistry 37 (15), 5086-5095, 1998 | 205 | 1998 |
The INPHARMA method: protein-mediated interligand NOEs for pharmacophore mapping VM Sánchez-Pedregal, M Reese, J Meiler, MJJ Blommers, C Griesinger, ... Angewandte Chemie-International Edition 44 (27), 4172-4174, 2005 | 204 | 2005 |
Effects of base sequence on the loop folding in DNA hairpins MJJ Blommers, J Walters, CAG Haasnoot, JMA Aelen, GA Van der Marel, ... Biochemistry 28 (18), 7491-7498, 1989 | 163 | 1989 |
Characterization of the mechanism of action of the pan class I PI3K inhibitor NVP-BKM120 across a broad range of concentrations SM Brachmann, J Kleylein-Sohn, S Gaulis, A Kauffmann, MJJ Blommers, ... Molecular cancer therapeutics 11 (8), 1747-1757, 2012 | 144 | 2012 |
The High‐Resolution Solution Structure of Epothilone A Bound to Tubulin: An Understanding of the Structure–Activity Relationships for a Powerful Class of Antitumor Agents T Carlomagno, MJJ Blommers, J Meiler, W Jahnke, T Schupp, F Petersen, ... Angewandte Chemie 115 (22), 2615-2619, 2003 | 129 | 2003 |
The four terminal components of the complement system AreC-mannosylated on multiple tryptophan residues J Hofsteenge, M Blommers, D Hess, A Furmanek, O Miroshnichenko Journal of Biological Chemistry 274 (46), 32786-32794, 1999 | 127 | 1999 |
Creating RNA bulges: cleavage of RNA in RNA/DNA duplexes by metal ion catalysis D Hüsken, G Goodall, MJJ Blommers, W Jahnke, J Hall, R Häner, ... Biochemistry 35 (51), 16591-16600, 1996 | 117 | 1996 |
The three‐dimensional structure of a DNA hairpin in solution: Two‐dimensional NMR studies and structural analysis of d (ATCCTATTTATAGGAT) MJJ Blommers, FJM Van De Ven, GA Van Der Marel, JH Van Boom, ... European journal of biochemistry 201 (1), 33-51, 1991 | 112 | 1991 |
L-DNAs as potenital antimessenger oligonucleotides: a reassessment A Garbesi, ML Capobinanco, FP Colonna, L Tondelli, F Arcamone, ... Nucleic acids research 21 (18), 4159-4165, 1993 | 108 | 1993 |
Crystal structure of human estrogen-related receptor α in complex with a synthetic inverse agonist reveals its novel molecular mechanism J Kallen, R Lattmann, R Beerli, A Blechschmidt, MJJ Blommers, M Geiser, ... Journal of Biological Chemistry 282 (32), 23231-23239, 2007 | 105 | 2007 |
Structural basis of the activity of the microtubule‐stabilizing agent epothilone a studied by NMR spectroscopy in solution M Reese, VM Sánchez‐Pedregal, K Kubicek, J Meiler, MJJ Blommers, ... Angewandte Chemie International Edition 46 (11), 1864-1868, 2007 | 105 | 2007 |
Recombinant human interleukin-12 is the second example of a C-mannosylated protein MA Doucey, D Hess, MJJ Blommers, J Hofsteenge Glycobiology 9 (5), 435-441, 1999 | 105 | 1999 |
Effects of the Introduction of L-Nucleotides into DNA. Solution Structure of the Heterochiral Duplex d (GCG-(L) TGCG). cntdot. d (CGCACGC) Studied by NMR Spectroscopy MJJ Blommers, L Tondelli, A Garbesi Biochemistry 33 (25), 7886-7896, 1994 | 101 | 1994 |
Conformational analysis of a dinucleotide photodimer with the aid of the genetic algorithm MJJ Blommers, CB Lucasius, G Kateman, R Kaptein Biopolymers: Original Research on Biomolecules 32 (1), 45-52, 1992 | 101 | 1992 |
Lipid− protein nanodiscs as reference medium in detergent screening for high-resolution NMR studies of integral membrane proteins ZO Shenkarev, EN Lyukmanova, AS Paramonov, LN Shingarova, ... Journal of the American Chemical Society 132 (16), 5628-5629, 2010 | 99 | 2010 |
Dual recognition of double-stranded DNA by 2 ‘-aminoethoxy-modified oligonucleotides: the solution structure of an intramolecular triplex obtained by NMR spectroscopy MJJ Blommers, F Natt, W Jahnke, B Cuenoud Biochemistry 37 (51), 17714-17725, 1998 | 95 | 1998 |
Second-site NMR screening and linker design W Jahnke, A Florsheimer, MJJ Blommers, C Paris, J Heim, CM Nalin, ... Current Topics in Medicinal Chemistry 3 (1), 69-80, 2003 | 83 | 2003 |
An approach to the structure determination of nucleic acid analogues hybridized to RNA. NMR studies of a duplex between 2′-OMe RNA and an oligonucleotide containing a single … MJJ Blommers, U Pieles, A Mesmaeker Nucleic acids research 22 (20), 4187-4194, 1994 | 82 | 1994 |