Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators SST Lee, T Pineau, J Drago, EJ Lee, JW Owens, DL Kroetz, ... Molecular and cellular biology 15 (6), 3012-3022, 1995 | 1984 | 1995 |
Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor P Fernandez-Salguero, T Pineau, DM Hilbert, T McPhail, SST Lee, ... Science 268 (5211), 722-726, 1995 | 1373 | 1995 |
The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. S Kimura, Y Hara, T Pineau, P Fernandez-Salguero, CH Fox, JM Ward, ... Genes & development 10 (1), 60-69, 1996 | 1330 | 1996 |
Aryl-hydrocarbon receptor-deficient mice are resistant to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced toxicity PM Fernandez-Salguero, DM Hilbert, S Rudikoff, JM Ward, FJ Gonzalez Toxicology and applied pharmacology 140 (1), 173-179, 1996 | 1073 | 1996 |
Role of CYP2E1 in the Hepatotoxicity of Acetaminophen (∗) SST Lee, JTM Buters, T Pineau, P Fernandez-Salguero, FJ Gonzalez Journal of Biological Chemistry 271 (20), 12063-12067, 1996 | 818 | 1996 |
Genomic instability in Gadd45a-deficient mice MC Hollander, MS Sheikh, DV Bulavin, K Lundgren, L Augeri-Henmueller, ... Nature genetics 23 (2), 176-184, 1999 | 636 | 1999 |
The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein R Barouki, X Coumoul, PM Fernandez-Salguero FEBS letters 581 (19), 3608-3615, 2007 | 503 | 2007 |
Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity. X Wei, HL McLeod, J McMurrough, FJ Gonzalez, P Fernandez-Salguero The Journal of clinical investigation 98 (3), 610-615, 1996 | 482 | 1996 |
Lesions of aryl-hydrocarbon receptor–deficient mice PM Fernandez-Salguero, JM Ward, JP Sundberg, FJ Gonzalez Veterinary pathology 34 (6), 605-614, 1997 | 473 | 1997 |
The aryl hydrocarbon receptor: studies using the AHR-null mice FJ Gonzalez, P Fernandez-Salguero Drug Metabolism and Disposition 26 (12), 1194-1198, 1998 | 469 | 1998 |
Targeted Genomic Disruption of H-ras and N-ras, Individually or in Combination, Reveals the Dispensability of Both Loci for Mouse Growth and Development LM Esteban, C Vicario-Abejón, P Fernández-Salguero, ... Molecular and cellular biology 21 (5), 1444-1452, 2001 | 416 | 2001 |
A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A gnes and identification of variant CYP2A6 alleles P Fernandez-Salguero, SMG Hoffman, S Cholerton, H Mohrenweiser, ... American Journal of Human Genetics 57 (3), 651, 1995 | 381 | 1995 |
Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy H Furuya, P Fernandez-Salguero, W Gregory, H Taber, A Steward, ... Pharmacogenetics and Genomics 5 (6), 389-392, 1995 | 354 | 1995 |
Resveratrol‐induced apoptosis in MCF‐7 human breast cancer cells involves a caspase‐independent mechanism with downregulation of Bcl‐2 and NF‐κB E Pozo‐Guisado, JM Merino, S Mulero‐Navarro, MJ Lorenzo‐Benayas, ... International journal of cancer 115 (1), 74-84, 2005 | 324 | 2005 |
The antiproliferative activity of resveratrol results in apoptosis in MCF-7 but not in MDA-MB-231 human breast cancer cells: cell-specific alteration of the cell cycle E Pozo-Guisado, A Alvarez-Barrientos, S Mulero-Navarro, ... Biochemical pharmacology 64 (9), 1375-1386, 2002 | 322 | 2002 |
New trends in aryl hydrocarbon receptor biology S Mulero-Navarro, PM Fernandez-Salguero Frontiers in cell and developmental biology 4, 45, 2016 | 288 | 2016 |
Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon receptor (AhR)-null mice. JM Peters, MG Narotsky, G Elizondo, PM Fernandez-Salguero, ... Toxicological sciences: an official journal of the Society of Toxicology 47 …, 1999 | 287 | 1999 |
Mechanisms involved in resveratrol‐induced apoptosis and cell cycle arrest in prostate cancer—derived cell lines DA Benitez, E Pozo‐Guisado, A Alvarez‐Barrientos, ... Journal of andrology 28 (2), 282-293, 2007 | 240 | 2007 |
Targeted disruption of the microsomal epoxide hydrolase gene: microsomal epoxide hydrolase is required for the carcinogenic activity of 7, 12-dimethylbenz [a] anthracene M Miyata, G Kudo, YH Lee, P Fernandez-Salguero, S Kimura, ... Journal of biological chemistry 274 (34), 23963-23968, 1999 | 239 | 1999 |
Altered cell cycle control at the G2/M phases in aryl hydrocarbon receptor-null embryo fibroblast G Elizondo, P Fernandez-Salguero, MS Sheikh, GY Kim, AJ Fornace, ... Molecular pharmacology 57 (5), 1056-1063, 2000 | 231 | 2000 |