Carbonic anhydrase inhibitors CT Supuran, A Scozzafava, A Casini Medicinal research reviews 23 (2), 146-189, 2003 | 1568* | 2003 |
Anticancer and antiviral sulfonamides A Scozzafava, T Owa, A Mastrolorenzo, CT Supuran Current medicinal chemistry 10 (11), 925-953, 2003 | 873 | 2003 |
Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors Y Lou, PC McDonald, A Oloumi, S Chia, C Ostlund, A Ahmadi, A Kyle, ... Cancer research 71 (9), 3364-3376, 2011 | 791 | 2011 |
Carbonic anhydrases as targets for medicinal chemistry CT Supuran, A Scozzafava Bioorganic & medicinal chemistry 15 (13), 4336-4350, 2007 | 731 | 2007 |
Carbonic anhydrase inhibitors and their therapeutic potential CT Supuran, A Scozzafava Expert Opinion on Therapeutic Patents 10 (5), 575-600, 2000 | 689 | 2000 |
Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH E Švastová, A Hulı́ková, M Rafajová, M Zat'ovičová, A Gibadulinová, ... FEBS letters 3 (577), 439-445, 2004 | 682 | 2004 |
Protease inhibitors of the sulfonamide type: anticancer, antiinflammatory, and antiviral agents CT Supuran, A Casini, A Scozzafava Medicinal Research Reviews 23 (5), 535-558, 2003 | 576 | 2003 |
Carbonic anhydrase: its inhibitors and activators CT Supuran, A Scozzafava, J Conway CRC press, 2004 | 574* | 2004 |
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX V Alterio, M Hilvo, A Di Fiore, CT Supuran, P Pan, S Parkkila, A Scaloni, ... Proceedings of the National Academy of Sciences 106 (38), 16233-16238, 2009 | 572 | 2009 |
Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors A Maresca, C Temperini, H Vu, NB Pham, SA Poulsen, A Scozzafava, ... Journal of the American Chemical Society 131 (8), 3057-3062, 2009 | 567 | 2009 |
Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition A Weber, A Casini, A Heine, D Kuhn, CT Supuran, A Scozzafava, G Klebe Journal of medicinal chemistry 47 (3), 550-557, 2004 | 549 | 2004 |
Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis F Pacchiano, F Carta, PC McDonald, Y Lou, D Vullo, A Scozzafava, ... Journal of medicinal chemistry 54 (6), 1896-1902, 2011 | 533 | 2011 |
Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins A Maresca, C Temperini, L Pochet, B Masereel, A Scozzafava, ... Journal of medicinal chemistry 53 (1), 335-344, 2010 | 458 | 2010 |
Carbonic anhydrase inhibitors CT Supuran, A Scozzafava Current Medicinal Chemistry-Immunology, Endocrine & Metabolic Agents 1 (1 …, 2001 | 437 | 2001 |
Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes M Hilvo, L Baranauskiene, AM Salzano, A Scaloni, D Matulis, A Innocenti, ... Journal of Biological Chemistry 283 (41), 27799-27809, 2008 | 378 | 2008 |
Carbonic anhydrase inhibitors: sulfonamides as antitumor agents? CT Supuran, F Briganti, S Tilli, WR Chegwidden, A Scozzafava Bioorganic & medicinal chemistry 9 (3), 703-714, 2001 | 368 | 2001 |
Applications of carbonic anhydrase inhibitors and activators in therapy CT Supuran, A Scozzafava Expert Opinion on Therapeutic Patents 12 (2), 217-242, 2002 | 367 | 2002 |
Sulfonamides and sulfonylated derivatives as anticancer agents A Scozzafava, A Mastrolorenzo, CT Supuran Current cancer drug targets 2 (1), 55-75, 2002 | 355 | 2002 |
Carbonic anhydrase and matrix metalloproteinase inhibitors: sulfonylated amino acid hydroxamates with MMP inhibitory properties act as efficient inhibitors of CA isozymes I, II … A Scozzafava, CT Supuran Journal of medicinal Chemistry 43 (20), 3677-3687, 2000 | 354 | 2000 |
Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic … A Scozzafava, L Menabuoni, F Mincione, F Briganti, G Mincione, ... Journal of medicinal chemistry 42 (14), 2641-2650, 1999 | 354 | 1999 |