A guide to immunometabolism for immunologists LAJ O'Neill, RJ Kishton, J Rathmell Nature reviews immunology 16 (9), 553-565, 2016 | 2860 | 2016 |
Identification of essential genes for cancer immunotherapy SJ Patel, NE Sanjana, RJ Kishton, A Eidizadeh, SK Vodnala, M Cam, ... Nature 548 (7669), 537-542, 2017 | 902 | 2017 |
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation VA Gerriets, RJ Kishton, AG Nichols, AN Macintyre, M Inoue, O Ilkayeva, ... The Journal of clinical investigation 125 (1), 194-207, 2015 | 740 | 2015 |
Distinct regulation of Th17 and Th1 cell differentiation by glutaminase-dependent metabolism MO Johnson, MM Wolf, MZ Madden, G Andrejeva, A Sugiura, ... Cell 175 (7), 1780-1795. e19, 2018 | 621 | 2018 |
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression VA Gerriets, RJ Kishton, MO Johnson, S Cohen, PJ Siska, AG Nichols, ... Nature immunology 17 (12), 1459-1466, 2016 | 529 | 2016 |
Metabolic regulation of T cell longevity and function in tumor immunotherapy RJ Kishton, M Sukumar, NP Restifo Cell metabolism 26 (1), 94-109, 2017 | 511 | 2017 |
T cell stemness and dysfunction in tumors are triggered by a common mechanism SK Vodnala, R Eil, RJ Kishton, M Sukumar, TN Yamamoto, NH Ha, ... Science 363 (6434), eaau0135, 2019 | 477 | 2019 |
mTORC1 and mTORC2 kinase signaling and glucose metabolism drive follicular helper T cell differentiation HU Zeng, S Cohen, C Guy, S Shrestha, G Neale, SA Brown, C Cloer, ... Immunity 45 (3), 540-554, 2016 | 345 | 2016 |
AMPK is essential to balance glycolysis and mitochondrial metabolism to control T-ALL cell stress and survival RJ Kishton, CE Barnes, AG Nichols, S Cohen, VA Gerriets, PJ Siska, ... Cell metabolism 23 (4), 649-662, 2016 | 251 | 2016 |
Developing neoantigen-targeted T cell–based treatments for solid tumors TN Yamamoto, RJ Kishton, NP Restifo Nature medicine 25 (10), 1488-1499, 2019 | 239 | 2019 |
The bone marrow protects and optimizes immunological memory during dietary restriction N Collins, SJ Han, M Enamorado, VM Link, B Huang, EA Moseman, ... Cell 178 (5), 1088-1101. e15, 2019 | 236 | 2019 |
T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy TN Yamamoto, PH Lee, SK Vodnala, D Gurusamy, RJ Kishton, Z Yu, ... The Journal of clinical investigation 129 (4), 1551-1565, 2019 | 160 | 2019 |
Suppression of Glut1 and glucose metabolism by decreased Akt/mTORC1 signaling drives T cell impairment in B cell leukemia PJ Siska, GJW van der Windt, RJ Kishton, S Cohen, W Eisner, NJ MacIver, ... The Journal of Immunology 197 (6), 2532-2540, 2016 | 159 | 2016 |
Multi-phenotype CRISPR-Cas9 screen identifies p38 kinase as a target for adoptive immunotherapies D Gurusamy, AN Henning, TN Yamamoto, Z Yu, N Zacharakis, S Krishna, ... Cancer cell 37 (6), 818-833. e9, 2020 | 148 | 2020 |
Metabolic stress is a barrier to Epstein–Barr virus-mediated B-cell immortalization K McFadden, AY Hafez, R Kishton, JE Messinger, PA Nikitin, JC Rathmell, ... Proceedings of the National Academy of Sciences 113 (6), E782-E790, 2016 | 132 | 2016 |
Leptin directly promotes T‐cell glycolytic metabolism to drive effector T‐cell differentiation in a mouse model of autoimmunity VA Gerriets, K Danzaki, RJ Kishton, W Eisner, AG Nichols, DC Saucillo, ... European journal of immunology 46 (8), 1970-1983, 2016 | 126 | 2016 |
Genome-wide screens identify lineage-and tumor-specific genes modulating MHC-I-and MHC-II-restricted immunosurveillance of human lymphomas D Dersh, JD Phelan, ME Gumina, B Wang, JH Arbuckle, J Holly, ... Immunity 54 (1), 116-131. e10, 2021 | 119 | 2021 |
Ribosomal proteins regulate MHC class I peptide generation for immunosurveillance J Wei, RJ Kishton, M Angel, CS Conn, N Dalla-Venezia, V Marcel, ... Molecular cell 73 (6), 1162-1173. e5, 2019 | 112 | 2019 |
Metabolic reprograming of anti-tumor immunity M Sukumar, RJ Kishton, NP Restifo Current opinion in immunology 46, 14-22, 2017 | 104 | 2017 |
Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis T Liu, RJ Kishton, AN Macintyre, VA Gerriets, H Xiang, X Liu, ED Abel, ... Cell death & disease 5 (10), e1470-e1470, 2014 | 88 | 2014 |