Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice JM Welch, J Lu, RM Rodriguiz, NC Trotta, J Peca, JD Ding, C Feliciano, ... Nature 448 (7156), 894-900, 2007 | 924 | 2007 |
Automated design of ligands to polypharmacological profiles J Besnard, GF Ruda, V Setola, K Abecassis, RM Rodriguiz, XP Huang, ... Nature 492 (7428), 215-220, 2012 | 876 | 2012 |
Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3 X Wang, PA McCoy, RM Rodriguiz, Y Pan, HS Je, AC Roberts, CJ Kim, ... Human molecular genetics 20 (15), 3093-3108, 2011 | 631 | 2011 |
Role of GSK3β in behavioral abnormalities induced by serotonin deficiency JM Beaulieu, X Zhang, RM Rodriguiz, TD Sotnikova, MJ Cools, ... Proceedings of the National Academy of Sciences 105 (4), 1333-1338, 2008 | 466 | 2008 |
A β-arrestin 2 signaling complex mediates lithium action on behavior JM Beaulieu, S Marion, RM Rodriguiz, IO Medvedev, TD Sotnikova, ... Cell 132 (1), 125-136, 2008 | 450 | 2008 |
Different presynaptic roles of synapsins at excitatory and inhibitory synapses D Gitler, Y Takagishi, J Feng, Y Ren, RM Rodriguiz, WC Wetsel, ... Journal of Neuroscience 24 (50), 11368-11380, 2004 | 393 | 2004 |
N-desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, as a putative mediator of quetiapine's antidepressant activity NH Jensen, RM Rodriguiz, MG Caron, WC Wetsel, RB Rothman, BL Roth Neuropsychopharmacology 33 (10), 2303-2312, 2008 | 390 | 2008 |
Relative abundance of Akkermansia spp. and other bacterial phylotypes correlates with anxiety- and depressive-like behavior following social defeat in mice KD McGaughey, T Yilmaz-Swenson, NM Elsayed, DA Cruz, RM Rodriguiz, ... Scientific reports 9 (1), 3281, 2019 | 374 | 2019 |
Long-term treatment of osteopetrosis with recombinant human interferon gamma LL Key Jr, RM Rodriguiz, SM Willi, NM Wright, HC Hatcher, DR Eyre, ... New England Journal of Medicine 332 (24), 1594-1599, 1995 | 353 | 1995 |
Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism X Wang, AL Bey, BM Katz, A Badea, N Kim, LK David, LJ Duffney, ... Nature communications 7 (1), 11459, 2016 | 335 | 2016 |
Aberrant responses in social interaction of dopamine transporter knockout mice RM Rodriguiz, R Chu, MG Caron, WC Wetsel Behavioural brain research 148 (1-2), 185-198, 2004 | 258 | 2004 |
Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice TM Griffin, B Fermor, JL Huebner, VB Kraus, RM Rodriguiz, WC Wetsel, ... Arthritis research & therapy 12, 1-18, 2010 | 241 | 2010 |
MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants JV Deng, RM Rodriguiz, AN Hutchinson, IH Kim, WC Wetsel, AE West Nature neuroscience 13 (9), 1128-1136, 2010 | 226 | 2010 |
Transient inhibition of TrkB kinase after status epilepticus prevents development of temporal lobe epilepsy G Liu, B Gu, XP He, RB Joshi, HD Wackerle, RM Rodriguiz, WC Wetsel, ... Neuron 79 (1), 31-38, 2013 | 212 | 2013 |
Cerebellar defects in Ca2+/calmodulin kinase IV-deficient mice TJ Ribar, RM Rodriguiz, L Khiroug, WC Wetsel, GJ Augustine, AR Means The Journal of Neuroscience 20 (22), RC107, 2000 | 209 | 2000 |
Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation AC Roberts, J Díez-García, RM Rodriguiz, IP López, R Luján, ... Neuron 63 (3), 342-356, 2009 | 188 | 2009 |
Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy EK Ruzzo, JM Capo-Chichi, B Ben-Zeev, D Chitayat, H Mao, AL Pappas, ... Neuron 80 (2), 429-441, 2013 | 184 | 2013 |
Vmat2 heterozygous mutant mice display a depressive-like phenotype M Fukui, RM Rodriguiz, J Zhou, SX Jiang, LE Phillips, MG Caron, ... Journal of Neuroscience 27 (39), 10520-10529, 2007 | 175 | 2007 |
Novelty seeking and stereotypic activation of behavior in mice with disruption of the Dat1 gene VM Pogorelov, RM Rodriguiz, ML Insco, MG Caron, WC Wetsel Neuropsychopharmacology 30 (10), 1818-1831, 2005 | 173 | 2005 |
Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity AL Kaplan, DN Confair, K Kim, X Barros-Álvarez, RM Rodriguiz, Y Yang, ... Nature 610 (7932), 582-591, 2022 | 170 | 2022 |