| Three-dimensional cluster analysis identifies interfaces and functional residue clusters in proteins R Landgraf, I Xenarios, D Eisenberg Journal of Molecular Biology 307 (5), 1487-1502, 2001 | 293 | 2001 |
| Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3 CHB Chen, GA Chernis, VQ Hoang, R Landgraf Proceedings of the National Academy of Sciences 100 (16), 9226-9231, 2003 | 286 | 2003 |
| Signaling through ERBB receptors: multiple layers of diversity and control CM Warren, R Landgraf Cellular signalling 18 (7), 923-933, 2006 | 178 | 2006 |
| Artificial nucleases CB Chen, L Milne, R Landgraf, DM Perrin, DS Sigman ChemBioChem 2 (10), 735-740, 2001 | 125 | 2001 |
| HER2 therapy. HER2 (ERBB2): functional diversity from structurally conserved building blocks R Landgraf Breast Cancer Research 9, 1-8, 2007 | 98 | 2007 |
| Analysis of heregulin symmetry by weighted evolutionary tracing R Landgraf, D Fischer, D Eisenberg Protein engineering 12 (11), 943-951, 1999 | 94 | 1999 |
| Molecular mechanism of protein kinase recognition and sorting by the Hsp90 kinome-specific cochaperone Cdc37 D Keramisanou, A Aboalroub, Z Zhang, W Liu, D Marshall, A Diviney, ... Molecular cell 62 (2), 260-271, 2016 | 91 | 2016 |
| Structure of the Escherichia coli Fis-DNA complex probed by protein conjugated with 1, 10-phenanthroline copper (I) complex. CQ Pan, JA Feng, SE Finkel, R Landgraf, D Sigman, RC Johnson Proceedings of the National Academy of Sciences 91 (5), 1721-1725, 1994 | 91 | 1994 |
| Functional isolation of activated and unilaterally phosphorylated heterodimers of ERBB2 and ERBB3 as scaffolds in ligand-dependent signaling Q Zhang, E Park, K Kani, R Landgraf Proceedings of the National Academy of Sciences 109 (33), 13237-13242, 2012 | 85 | 2012 |
| Nucleic acid chemistry of the cuprous complexes of 1, 10-phenanthroline and derivatives DS Sigman, R Landgraf, DM Perrin, L Pearson Metal ions in biological systems 33, 485-514, 1996 | 81 | 1996 |
| Oligomers of ERBB3 have two distinct interfaces that differ in their sensitivity to disruption by heregulin K Kani, CM Warren, CS Kaddis, JA Loo, R Landgraf Journal of Biological Chemistry 280 (9), 8238-8247, 2005 | 80 | 2005 |
| Identification of a heregulin binding site in HER3 extracellular domain E Singer, R Landgraf, T Horan, D Slamon, D Eisenberg Journal of Biological Chemistry 276 (47), 44266-44274, 2001 | 80 | 2001 |
| The small molecule IMR-1 inhibits the notch transcriptional activation complex to suppress tumorigenesis L Astudillo, TG Da Silva, Z Wang, X Han, K Jin, J VanWye, X Zhu, ... Cancer research 76 (12), 3593-3603, 2016 | 76 | 2016 |
| Heregulin reverses the oligomerization of HER3 R Landgraf, D Eisenberg Biochemistry 39 (29), 8503-8511, 2000 | 75 | 2000 |
| PI3K independent activation of mTORC1 as a target in lapatinib-resistant ERBB2+ breast cancer cells AM Jegg, TM Ward, E Iorns, N Hoe, JY Zhou, X Liu, S Singh, R Landgraf, ... Breast cancer research and treatment 136, 683-692, 2012 | 53 | 2012 |
| Truncated p110 ERBB2 induces mammary epithelial cell migration, invasion and orthotopic xenograft formation, and is associated with loss of phosphorylated STAT5 TM Ward, E Iorns, X Liu, N Hoe, P Kim, S Singh, S Dean, AM Jegg, ... Oncogene 32 (19), 2463-2474, 2013 | 49 | 2013 |
| Dynamic analysis of the epidermal growth factor (EGF) receptor-ErbB2-ErbB3 protein network by luciferase fragment complementation imaging JL Macdonald-Obermann, S Adak, R Landgraf, D Piwnica-Worms, LJ Pike Journal of Biological Chemistry 288 (42), 30773-30784, 2013 | 48 | 2013 |
| Regulation of receptor for advanced glycation end products (RAGE) ectodomain shedding and its role in cell function A Braley, T Kwak, J Jules, E Harja, R Landgraf, BI Hudson Journal of Biological Chemistry 291 (23), 12057-12073, 2016 | 44 | 2016 |
| Higher-order association states of cellular ERBB3 probed with photo-cross-linkable aptamers E Park, R Baron, R Landgraf Biochemistry 47 (46), 11992-12005, 2008 | 41 | 2008 |
| Human ERK1 induces filamentous growth and cell wall remodeling pathways in Saccharomyces cerevisiae JM Atienza, M Suh, I Xenarios, R Landgraf, J Colicelli Journal of Biological Chemistry 275 (27), 20638-20646, 2000 | 41 | 2000 |
David S. EisenbergPaul Boyer Professor, HHMI-UCLAכתובת אימייל מאומתת בדומיין mbi.ucla.edu
