| Membrane transporters in drug development Nature reviews Drug discovery 9 (3), 215-236, 2010 | 3631 | 2010 |
| Systemic availability and metabolism of colonic‐derived short‐chain fatty acids in healthy subjects: a stable isotope study E Boets, SV Gomand, L Deroover, T Preston, K Vermeulen, V De Preter, ... The Journal of physiology 595 (2), 541-555, 2017 | 405 | 2017 |
| Ordered mesoporous silica material SBA-15: a broad-spectrum formulation platform for poorly soluble drugs M Van Speybroeck, V Barillaro, T Do Thi, R Mellaerts, J Martens, ... Journal of pharmaceutical sciences 98 (8), 2648-2658, 2009 | 317 | 2009 |
| Strategies for absorption screening in drug discovery and development H Bohets, P Annaert, G Mannens, K Anciaux, P Verboven, ... Current topics in medicinal chemistry 1 (5), 367-383, 2001 | 299 | 2001 |
| Favipiravir at high doses has potent antiviral activity in SARS-CoV-2− infected hamsters, whereas hydroxychloroquine lacks activity SJF Kaptein, S Jacobs, L Langendries, L Seldeslachts, S Ter Horst, ... Proceedings of the National Academy of Sciences 117 (43), 26955-26965, 2020 | 294 | 2020 |
| Increasing the oral bioavailability of the poorly water soluble drug itraconazole with ordered mesoporous silica R Mellaerts, R Mols, JAG Jammaer, CA Aerts, P Annaert, ... European Journal of Pharmaceutics and Biopharmaceutics 69 (1), 223-230, 2008 | 292 | 2008 |
| Enhanced absorption of the poorly soluble drug fenofibrate by tuning its release rate from ordered mesoporous silica M Van Speybroeck, R Mellaerts, R Mols, T Do Thi, JA Martens, ... European Journal of Pharmaceutical Sciences 41 (5), 623-630, 2010 | 247 | 2010 |
| The FXR agonist obeticholic acid prevents gut barrier dysfunction and bacterial translocation in cholestatic rats L Verbeke, R Farre, B Verbinnen, K Covens, T Vanuytsel, J Verhaegen, ... The American journal of pathology 185 (2), 409-419, 2015 | 228 | 2015 |
| A review of drug solubility in human intestinal fluids: implications for the prediction of oral absorption P Augustijns, B Wuyts, B Hens, P Annaert, J Butler, J Brouwers European Journal of Pharmaceutical Sciences 57, 322-332, 2014 | 208 | 2014 |
| Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B1 P Annaert, ZW Ye, B Stieger, P Augustijns Xenobiotica 40 (3), 163-176, 2010 | 198 | 2010 |
| Antiretroviral efficacy and pharmacokinetics of oral bis (isopropyloxycarbonyloxymethyl) 9-(2-phosphonylmethoxypropyl) adenine in mice L Naesens, N Bischofberger, P Augustijns, P Annaert, G Van den Mooter, ... Antimicrobial agents and chemotherapy 42 (7), 1568-1573, 1998 | 180 | 1998 |
| Clinical determinants of calcineurin inhibitor disposition: a mechanistic review T Vanhove, P Annaert, DRJ Kuypers Drug metabolism reviews 48 (1), 88-112, 2016 | 173 | 2016 |
| Excipient-mediated supersaturation stabilization in human intestinal fluids J Bevernage, T Forier, J Brouwers, J Tack, P Annaert, P Augustijns Molecular pharmaceutics 8 (2), 564-570, 2011 | 173 | 2011 |
| Effect of pH and comedication on gastrointestinal absorption of posaconazole: monitoring of intraluminal and plasma drug concentrations J Walravens, J Brouwers, I Spriet, J Tack, P Annaert, P Augustijns Clinical pharmacokinetics 50, 725-734, 2011 | 156 | 2011 |
| Pharmacokinetics of caspofungin and voriconazole in critically ill patients during extracorporeal membrane oxygenation I Spriet, P Annaert, P Meersseman, G Hermans, W Meersseman, ... Journal of antimicrobial chemotherapy 63 (4), 767-770, 2009 | 153 | 2009 |
| High intrapatient variability of tacrolimus concentrations predicts accelerated progression of chronic histologic lesions in renal recipients T Vanhove, T Vermeulen, P Annaert, E Lerut, DRJ Kuypers American Journal of Transplantation 16 (10), 2954-2963, 2016 | 147 | 2016 |
| In vitro hepatic metabolism explains higher clearance of voriconazole in children versus adults: role of CYP2C19 and flavin-containing monooxygenase 3 SB Yanni, PP Annaert, P Augustijns, JG Ibrahim, DK Benjamin Jr, ... Drug Metabolism and Disposition 38 (1), 25-31, 2010 | 147 | 2010 |
| Intestinal drug solubility estimation based on simulated intestinal fluids: comparison with solubility in human intestinal fluids S Clarysse, J Brouwers, J Tack, P Annaert, P Augustijns European Journal of Pharmaceutical Sciences 43 (4), 260-269, 2011 | 146 | 2011 |
| Structure-based identification of OATP1B1/3 inhibitors T De Bruyn, GJP Van Westen, AP IJzerman, B Stieger, P de Witte, ... Molecular pharmacology 83 (6), 1257-1267, 2013 | 145 | 2013 |
| Albumin is the main plasma binding protein for indoxyl sulfate and p‐cresyl sulfate L Viaene, P Annaert, H de Loor, R Poesen, P Evenepoel, B Meijers Biopharmaceutics & drug disposition 34 (3), 165-175, 2013 | 142 | 2013 |