NKX2-5eGFP/w hESCs for isolation of human cardiac progenitors and cardiomyocytes DA Elliott, SR Braam, K Koutsis, ES Ng, R Jenny, EL Lagerqvist, C Biben, ... Nature methods 8 (12), 1037-1040, 2011 | 524 | 2011 |
Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation ES Ng, RP Davis, L Azzola, EG Stanley, AG Elefanty Blood 106 (5), 1601-1603, 2005 | 502 | 2005 |
Human-iPSC-derived cardiac stromal cells enhance maturation in 3D cardiac microtissues and reveal non-cardiomyocyte contributions to heart disease E Giacomelli, V Meraviglia, G Campostrini, A Cochrane, X Cao, ... Cell Stem Cell 26 (6), 862-879. e11, 2020 | 470 | 2020 |
A protocol describing the use of a recombinant protein-based, animal product-free medium (APEL) for human embryonic stem cell differentiation as spin embryoid bodies ES Ng, R Davis, EG Stanley, AG Elefanty Nature protocols 3 (5), 768-776, 2008 | 383 | 2008 |
MUSCLEMOTION: a versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo L Sala, BJ Van Meer, LGJ Tertoolen, J Bakkers, M Bellin, RP Davis, ... Circulation research 122 (3), e5-e16, 2018 | 326 | 2018 |
Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease RP Davis, S Casini, CW van den Berg, M Hoekstra, CA Remme, ... Circulation 125 (25), 3079-3091, 2012 | 312 | 2012 |
Targeting a GFP reporter gene to the MIXL1 locus of human embryonic stem cells identifies human primitive streak–like cells and enables isolation of primitive … RP Davis, ES Ng, M Costa, AK Mossman, K Sourris, AG Elefanty, ... Blood, The Journal of the American Society of Hematology 111 (4), 1876-1884, 2008 | 275 | 2008 |
Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long‐QT syndrome M Bellin, S Casini, RP Davis, C D'aniello, J Haas, D Ward‐van Oostwaard, ... The EMBO journal 32 (24), 3161-3175, 2013 | 271 | 2013 |
Contractile defect caused by mutation in MYBPC3 revealed under conditions optimized for human PSC-cardiomyocyte function MJ Birket, MC Ribeiro, G Kosmidis, D Ward, AR Leitoguinho, V van de Pol, ... Cell reports 13 (4), 733-745, 2015 | 230 | 2015 |
Retinoic acid induces Pdx1-positive endoderm in differentiating mouse embryonic stem cells SJ Micallef, ME Janes, K Knezevic, RP Davis, AG Elefanty, EG Stanley Diabetes 54 (2), 301-305, 2005 | 204 | 2005 |
A method for genetic modification of human embryonic stem cells using electroporation M Costa, M Dottori, K Sourris, P Jamshidi, T Hatzistavrou, R Davis, ... Nature protocols 2 (4), 792-796, 2007 | 192 | 2007 |
Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development RP Davis, CW van den Berg, S Casini, SR Braam, CL Mummery Trends in molecular medicine 17 (9), 475-484, 2011 | 165 | 2011 |
Transcriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells CW Van Den Berg, S Okawa, SM Chuva de Sousa Lopes, L Van Iperen, ... Development 142 (18), 3231-3238, 2015 | 162 | 2015 |
Challenges in using stem cells for cardiac repair CL Mummery, RP Davis, JE Krieger Science translational medicine 2 (27), 27ps17-27ps17, 2010 | 141 | 2010 |
A Targeted NKX2.1 Human Embryonic Stem Cell Reporter Line Enables Identification of Human Basal Forebrain Derivatives AL Goulburn, D Alden, RP Davis, SJ Micallef, ES Ng, QC Yu, SM Lim, ... Stem cells 29 (3), 462-473, 2011 | 124 | 2011 |
NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network DJ Anderson, DI Kaplan, KM Bell, K Koutsis, JM Haynes, RJ Mills, ... Nature communications 9 (1), 1-13, 2018 | 117 | 2018 |
Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies KO Brandão, VA Tabel, DE Atsma, CL Mummery, RP Davis Disease models & mechanisms 10 (9), 1039-1059, 2017 | 112 | 2017 |
Dual Reporter MESP1mCherry/w‐NKX2‐5eGFP/w hESCs Enable Studying Early Human Cardiac Differentiation SC Den Hartogh, C Schreurs, JJ Monshouwer‐Kloots, RP Davis, ... Stem Cells 33 (1), 56-67, 2015 | 89 | 2015 |
SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development RJP Skelton, M Costa, DJ Anderson, F Bruveris, BW Finnin, K Koutsis, ... Stem cell research 13 (1), 172-179, 2014 | 87 | 2014 |
Generation, functional analysis and applications of isogenic three-dimensional self-aggregating cardiac microtissues from human pluripotent stem cells G Campostrini, V Meraviglia, E Giacomelli, RWJ van Helden, L Yiangou, ... Nature Protocols 16 (4), 2213-2256, 2021 | 77 | 2021 |