Signatures of mutational processes in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ... nature 500 (7463), 415-421, 2013 | 10343 | 2013 |
Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies A Antoniou, PDP Pharoah, S Narod, HA Risch, JE Eyfjord, JL Hopper, ... The American Journal of Human Genetics 72 (5), 1117-1130, 2003 | 4891 | 2003 |
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families D Ford, DF Easton, M Stratton, S Narod, D Goldgar, P Devilee, DT Bishop, ... The American Journal of Human Genetics 62 (3), 676-689, 1998 | 3990 | 1998 |
Landscape of somatic mutations in 560 breast cancer whole-genome sequences S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ... Nature 534 (7605), 47-54, 2016 | 2314 | 2016 |
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1923* | 2020 |
The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds SV Tavtigian, J Simard, J Rommens, F Couch, D Shattuck-Eidens, ... Nature genetics 12 (3), 333-337, 1996 | 1136 | 1996 |
HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures H Davies, D Glodzik, S Morganella, LR Yates, J Staaf, X Zou, ... Nature medicine 23 (4), 517-525, 2017 | 1016 | 2017 |
The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer. M Olivier, A Langer√∏ d, P Carrieri, J Bergh, S Klaar, J Eyfjord, ... Clinical cancer research: an official journal of the American Association …, 2006 | 710 | 2006 |
A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes S Thorlacius, G Olafsdottir, L Tryggvadottir, S Neuhausen, JG Jonasson, ... Nature genetics 13 (1), 117-119, 1996 | 665 | 1996 |
The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions AC Antoniou, AP Cunningham, J Peto, DG Evans, F Lalloo, SA Narod, ... British journal of cancer 98 (8), 1457-1466, 2008 | 645 | 2008 |
Population-based study of risk of breast cancer in carriers of BRCA2 mutation S Thorlacius, JP Struewing, P Hartage, GH Olafsdottir, H Sigvaldason, ... The Lancet 352 (9137), 1337-1339, 1998 | 486 | 1998 |
Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes. IBC Group, IBC Group Science 345 (345(6196):1251343), 2014 | 457 | 2014 |
Study of a single BRCA2 mutation with high carrier frequency in a small population. S Thorlacius, S Sigurdsson, H Bjarnadottir, G Olafsdottir, JG Jonasson, ... American journal of human genetics 60 (5), 1079, 1997 | 407 | 1997 |
Epigenetic silencing and deletion of the BRCA1gene in sporadic breast cancer V Birgisdottir, OA Stefansson, SK Bodvarsdottir, H Hilmarsdottir, ... Breast cancer research 8, 1-10, 2006 | 324 | 2006 |
Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study EK Bancroft, EC Page, E Castro, H Lilja, A Vickers, D Sjoberg, M Assel, ... European urology 66 (3), 489-499, 2014 | 303 | 2014 |
Somatic mutations reveal asymmetric cellular dynamics in the early human embryo YS Ju, I Martincorena, M Gerstung, M Petljak, LB Alexandrov, R Rahbari, ... Nature 543 (7647), 714-718, 2017 | 299 | 2017 |
The topography of mutational processes in breast cancer genomes S Morganella, LB Alexandrov, D Glodzik, X Zou, H Davies, J Staaf, ... Nature communications 7 (1), 11383, 2016 | 287 | 2016 |
Prostate cancer progression and survival in BRCA2 mutation carriers L Tryggvadóttir, L Vidarsdóttir, T Thorgeirsson, JG Jonasson, ... Journal of the National Cancer Institute 99 (12), 929-935, 2007 | 273 | 2007 |
Screening for Germ Line TP53 Mutations in Breast Cancer Patients AL Børresen, TI Andersen, J Garber, N Barbier-Piraux, S Thorlacius, ... Cancer research 52 (11), 3234-3236, 1992 | 243 | 1992 |
Interim results from the IMPACT study: evidence for prostate-specific antigen screening in BRCA2 mutation carriers EC Page, EK Bancroft, MN Brook, M Assel, MH Al Battat, S Thomas, ... European urology 76 (6), 831-842, 2019 | 234 | 2019 |