| Hepatoprotective effects of diosmin and/or sildenafil against cholestatic liver cirrhosis: The role of Keap-1/Nrf-2 and P38-MAPK/NF-κB/iNOS signaling pathway FEM Ali, AA Azouz, AG Bakr, AM Abo-Youssef, RAM Hemeida Food and Chemical Toxicology 120, 294-304, 2018 | 61 | 2018 |
| Coenzyme Q10 protects hepatocytes from ischemia reperfusion-induced apoptosis and oxidative stress via regulation of Bax/Bcl-2/PUMA and Nrf-2/FOXO-3/Sirt-1 signaling pathways AR Mahmoud, FEM Ali, TH Abd-Elhamid, EHM Hassanein Tissue and Cell 60, 1-13, 2019 | 56 | 2019 |
| Targeting Keap-1/Nrf-2 pathway and cytoglobin as a potential protective mechanism of diosmin and pentoxifylline against cholestatic liver cirrhosis FEM Ali, AG Bakr, AM Abo-Youssef, AA Azouz, RAM Hemeida Life sciences 207, 50-60, 2018 | 54 | 2018 |
| Umbelliferone attenuates gentamicin-induced renal toxicity by suppression of TLR-4/NF-κB-p65/NLRP-3 and JAK1/STAT-3 signaling pathways EHM Hassanein, FEM Ali, MR Kozman, OAM Abd El-Ghafar Environmental Science and Pollution Research 28, 11558-11571, 2021 | 49 | 2021 |
| Reno-protective effects of ursodeoxycholic acid against gentamicin-induced nephrotoxicity through modulation of NF-κB, eNOS and caspase-3 expressions TH Abd-Elhamid, DA Elgamal, SS Ali, FEM Ali, EHM Hassanein, ... Cell and tissue research 374, 367-387, 2018 | 49 | 2018 |
| Ursodeoxycholic acid abrogates gentamicin-induced hepatotoxicity in rats: Role of NF-κB-p65/TNF-α, Bax/Bcl-xl/Caspase-3, and eNOS/iNOS pathways FEM Ali, EHM Hassanein, AG Bakr, EAM El-Shoura, DA El-Gamal, ... Life sciences 254, 117760, 2020 | 47 | 2020 |
| Nephroprotective effect of umbelliferone against cisplatin‐induced kidney damage is mediated by regulation of NRF2, cytoglobin, SIRT1/FOXO‐3, and NF‐ kB‐p65 … FEM Ali, EHM Hassanein, AH El‐Bahrawy, ZMM Omar, EK Rashwan, ... Journal of Biochemical and Molecular Toxicology 35 (5), e22738, 2021 | 45 | 2021 |
| Rebamipide potentially mitigates methotrexate‐induced nephrotoxicity via inhibition of oxidative stress and inflammation: A molecular and histochemical study RA Elmansy, HS Seleem, AR Mahmoud, EHM Hassanein, FEM Ali The Anatomical Record 304 (3), 647-661, 2021 | 45 | 2021 |
| Targeting KEAP1/Nrf2, AKT, and PPAR-γ signals as a potential protective mechanism of diosmin against gentamicin-induced nephrotoxicity FEM Ali, AM Sayed, AH El-Bahrawy, ZMM Omar, EHM Hassanein Life Sciences 275, 119349, 2021 | 42 | 2021 |
| Roflumilast protects from cisplatin-induced testicular toxicity in male rats and enhances its cytotoxicity in prostate cancer cell line. Role of NF-κB-p65, cAMP/PKA and Nrf2/HO … BA Abdel-Wahab, IA Walbi, HA Albarqi, FEM Ali, EHM Hassanein Food and Chemical Toxicology 151, 112133, 2021 | 39 | 2021 |
| Perindopril Ameliorates Hepatic Ischemia Reperfusion Injury Via Regulation of NF‐κB‐p65/TLR‐4, JAK1/STAT‐3, Nrf‐2, and PI3K/Akt/mTOR Signaling Pathways EO Kamel, EHM Hassanein, MA Ahmed, FEM Ali The Anatomical Record 303 (7), 1935-1949, 2020 | 39 | 2020 |
| Hepatoprotective effect of rebamipide against methotrexate-induced hepatic intoxication: role of Nrf2/GSK-3β, NF-κβ-p65/JAK1/STAT3, and PUMA/Bax/Bcl-2 signaling pathways BA Abdel-Wahab, FEM Ali, SA Alkahtani, AM Alshabi, MH Mahnashi, ... Immunopharmacology and Immunotoxicology 42 (5), 493-503, 2020 | 37 | 2020 |
| Inhibition of NF-kB/IL-6/JAK2/STAT3 pathway and epithelial-mesenchymal transition in breast cancer cells by azilsartan R Alaaeldin, FEM Ali, AA Bekhit, QL Zhao, M Fathy Molecules 27 (22), 7825, 2022 | 34 | 2022 |
| Regulation of Keap-1/Nrf2/AKT and iNOS/NF-κB/TLR4 signals by apocynin abrogated methotrexate-induced testicular toxicity: Mechanistic insights and computational pharmacological … AM Sayed, EHM Hassanein, FEM Ali, ZMM Omar, EK Rashwan, ... Life sciences 284, 119911, 2021 | 30 | 2021 |
| Trans-ferulic acid ameliorates cisplatin-induced testicular damage via suppression of TLR4, P38-MAPK, and ERK1/2 signaling pathways EHM Hassanein, BA Abdel-Wahab, FEM Ali, OAM Abd El-Ghafar, ... Environmental Science and Pollution Research 28, 41948-41964, 2021 | 30 | 2021 |
| Berberine and/or zinc protect against methotrexate-induced intestinal damage: Role of GSK-3β/NRF2 and JAK1/STAT-3 signaling pathways EHM Hassanein, EO Kamel, FEM Ali, MAR Ahmed Life sciences 281, 119754, 2021 | 26 | 2021 |
| Impact of cytokine storm and systemic inflammation on liver impairment patients infected by SARS-CoV-2: Prospective therapeutic challenges FEM Ali, ZM Mohammedsaleh, MM Ali, OM Ghogar World journal of gastroenterology 27 (15), 1531, 2021 | 26 | 2021 |
| Hepatoprotective effect of acetovanillone against methotrexate hepatotoxicity: Role of Keap‐1/Nrf2/ARE, IL6/STAT‐3, and NF‐κB/AP‐1 signaling pathways OAM Abd El‐Ghafar, EHM Hassanein, FEM Ali, ZMM Omar, EK Rashwan, ... Phytotherapy Research 36 (1), 488-505, 2022 | 25 | 2022 |
| Azilsartan modulates HMGB1/NF-κB/p38/ERK1/2/JNK and apoptosis pathways during renal ischemia reperfusion injury R Alaaeldin, SM Bakkar, RH Mohyeldin, FEM Ali, NMR Abdel-Maqsoud, ... Cells 12 (1), 185, 2023 | 24 | 2023 |
| Quercetin potentiates the hepatoprotective effect of sildenafil and/or pentoxifylline against intrahepatic cholestasis: Role of Nrf2/ARE, TLR4/NF-κB, and NLRP3/IL-1β signaling … MA Fawzy, G Nasr, FEM Ali, M Fathy Life Sciences 314, 121343, 2023 | 22 | 2023 |
Emad H.M. HassaneinAssociate Professor of Pharmacology & Toxicology - Faculty of Pharmacy Al-Azhar Universityכתובת אימייל מאומתת בדומיין azhar.edu.eg
