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Michael R. Holbrook
Michael R. Holbrook
Battelle Memorial Institute/NIAID integrated Research Facility
Nessuna email verificata
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Anno
Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection
J Dyall, CM Coleman, T Venkataraman, MR Holbrook, J Kindrachuk, ...
Antimicrobial agents and chemotherapy 58 (8), 4885-4893, 2014
7492014
Antiviral potential of ERK/MAPK and PI3K/AKT/mTOR signaling modulation for Middle East respiratory syndrome coronavirus infection as identified by temporal kinome analysis
J Kindrachuk, B Ork, S Mazur, MR Holbrook, MB Frieman, D Traynor, ...
Antimicrobial agents and chemotherapy 59 (2), 1088-1099, 2015
4162015
A broad-spectrum antiviral targeting entry of enveloped viruses
MC Wolf, AN Freiberg, T Zhang, Z Akyol-Ataman, A Grock, PW Hong, J Li, ...
Proceedings of the National Academy of Sciences 107 (7), 3157-3162, 2010
3032010
Interferon-β and mycophenolic acid are potent inhibitors of Middle East respiratory syndrome coronavirus in cell-based assays
J Dyall, E Postnikova, H Zhou, J Kindrachuk, RF Johnson, GG Olinger Jr, ...
Journal of general virology 95 (3), 571-577, 2014
2872014
The NS5 protein of the virulent West Nile virus NY99 strain is a potent antagonist of type I interferon-mediated JAK-STAT signaling
M Laurent-Rolle, EF Boer, KJ Lubick, JB Wolfinbarger, AB Carmody, ...
Journal of virology 84 (7), 3503-3515, 2010
2812010
Possible sexual transmission of Ebola virus—Liberia, 2015
A Christie, GJ Davies-Wayne, T Cordier-Lasalle, DJ Blackley, AS Laney, ...
Morbidity and Mortality Weekly Report 64 (17), 479, 2015
2462015
Phosphoinositide-3 kinase-Akt pathway controls cellular entry of Ebola virus
MF Saeed, AA Kolokoltsov, AN Freiberg, MR Holbrook, RA Davey
PLoS pathogens 4 (8), e1000141, 2008
2332008
Biophysical characterization and vector-specific antagonist activity of domain III of the tick-borne flavivirus envelope protein
S Bhardwaj, M Holbrook, RE Shope, ADT Barrett, SJ Watowich
Journal of virology 75 (8), 4002-4007, 2001
1802001
Ubiquitin-regulated nuclear-cytoplasmic trafficking of the Nipah virus matrix protein is important for viral budding
YE Wang, A Park, M Lake, M Pentecost, B Torres, TE Yun, MC Wolf, ...
PLoS pathogens 6 (11), e1001186, 2010
1712010
Three-dimensional organization of Rift Valley fever virus revealed by cryoelectron tomography
AN Freiberg, MB Sherman, MC Morais, MR Holbrook, SJ Watowich
Journal of virology 82 (21), 10341-10348, 2008
1672008
Kyasanur forest disease
MR Holbrook
Antiviral research 96 (3), 353-362, 2012
1652012
Broadly neutralizing antibodies target the coronavirus fusion peptide
C Dacon, C Tucker, L Peng, CCD Lee, TH Lin, M Yuan, Y Cong, L Wang, ...
Science 377 (6607), 728-735, 2022
1642022
Historical perspectives on flavivirus research
MR Holbrook
Viruses 9 (5), 97, 2017
1642017
Defining the risk of SARS-CoV-2 variants on immune protection
MM DeGrace, E Ghedin, MB Frieman, F Krammer, A Grifoni, A Alisoltani, ...
Nature 605 (7911), 640-652, 2022
1532022
Antibody quality and protection from lethal Ebola virus challenge in nonhuman primates immunized with rabies virus based bivalent vaccine
JE Blaney, A Marzi, M Willet, AB Papaneri, C Wirblich, F Feldmann, ...
PLoS pathogens 9 (5), e1003389, 2013
1532013
Combined chloroquine and ribavirin treatment does not prevent death in a hamster model of Nipah and Hendra virus infection
AN Freiberg, MN Worthy, B Lee, MR Holbrook
Journal of General Virology 91 (3), 765-772, 2010
1482010
Solution structure and antibody binding studies of the envelope protein domain III from the New York strain of West Nile virus
DE Volk, DWC Beasley, DA Kallick, MR Holbrook, ADT Barrett, ...
Journal of Biological Chemistry 279 (37), 38755-38761, 2004
1382004
T-705 (favipiravir) inhibition of arenavirus replication in cell culture
M Mendenhall, A Russell, T Juelich, EL Messina, DF Smee, AN Freiberg, ...
Antimicrobial agents and chemotherapy 55 (2), 782-787, 2011
1322011
Single-particle cryo-electron microscopy of Rift Valley fever virus
MB Sherman, AN Freiberg, MR Holbrook, SJ Watowich
Virology 387 (1), 11-15, 2009
1322009
Inactivated or live-attenuated bivalent vaccines that confer protection against rabies and Ebola viruses
JE Blaney, C Wirblich, AB Papaneri, RF Johnson, CJ Myers, TL Juelich, ...
Journal of virology 85 (20), 10605-10616, 2011
1272011
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