Autophagy suppresses tumorigenesis through elimination of p62 R Mathew, CM Karp, B Beaudoin, N Vuong, G Chen, HY Chen, K Bray, ... Cell 137 (6), 1062-1075, 2009 | 2018 | 2009 |
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis JY Guo, HY Chen, R Mathew, J Fan, AM Strohecker, G Karsli-Uzunbas, ... Genes & development 25 (5), 460-470, 2011 | 1489 | 2011 |
Role of autophagy in cancer prevention HY Chen, E White Cancer Prevention Research 4 (7), 973-983, 2011 | 235 | 2011 |
Concurrent MEK2 Mutation and BRAF Amplification Confer Resistance to BRAF and MEK Inhibitors in Melanoma J Villanueva, JR Infante, C Krepler, P Reyes-Uribe, M Samanta, HY Chen, ... Cell reports 4 (6), 1090-1099, 2013 | 225 | 2013 |
Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition K Bray, R Mathew, A Lau, JJ Kamphorst, J Fan, J Chen, HY Chen, ... PloS one 7 (7), e41831, 2012 | 173 | 2012 |
Compounds from Wedelia chinensis synergistically suppress androgen activity and growth in prostate cancer cells FM Lin, LR Chen, EH Lin, FC Ke, HY Chen, MJ Tsai, PW Hsiao Carcinogenesis 28 (12), 2521-2529, 2007 | 149 | 2007 |
Bcl-2 modulation to activate apoptosis in prostate cancer K Bray, HY Chen, CM Karp, M May, S Ganesan, V Karantza-Wadsworth, ... Molecular Cancer Research 7 (9), 1487-1496, 2009 | 56 | 2009 |
Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma C Krepler, M Xiao, M Samanta, A Vultur, HY Chen, P Brafford, ... Oncotarget 7 (44), 71211, 2016 | 30 | 2016 |
Double Trouble: Kinase domain duplication as a new path to drug resistance HY Chen, DC Brady, J Villanueva Pigment Cell & Melanoma Research 29 (5), 493-495, 2016 | 7 | 2016 |
Playing Polo-Like Kinase in NRAS-Mutant Melanoma HY Chen, J Villanueva Journal of Investigative Dermatology 135 (10), 2352-2355, 2015 | 6 | 2015 |
Selective abrogation of S6K2 maps lipid homeostasis as a survival vulnerability in MAPKi-resistant NRASmut melanoma HY Chen, AR Goldman, D Zayas-Bazan, PI Reyes-Uribe, AN Guterres, ... bioRxiv, 2021 | 1 | 2021 |
Loss of S6K2 perturbs redox balance and fatty acid metabolism, leading to oxidative cell death HY Chen, M Samanta, P Reyes-Uribe, AV Kossenkov, X Yin, Y Lu, ... Cancer Research 78 (13 Supplement), 2381-2381, 2018 | 1 | 2018 |