| Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer Y Ino, R Yamazaki-Itoh, K Shimada, M Iwasaki, T Kosuge, Y Kanai, ... British journal of cancer 108 (4), 914-923, 2013 | 954 | 2013 |
| Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas. K Yoshiura, Y Kanai, A Ochiai, Y Shimoyama, T Sugimura, S Hirohashi Proceedings of the National Academy of Sciences 92 (16), 7416-7419, 1995 | 829 | 1995 |
| Cell adhesion system and human cancer morphogenesis S Hirohashi, Y Kanai Cancer science 94 (7), 575-581, 2003 | 628 | 2003 |
| The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery HG Stunnenberg, S Abrignani, D Adams, M de Almeida, L Altucci, V Amin, ... Cell 167 (5), 1145-1149, 2016 | 546 | 2016 |
| FOXP3+ regulatory T cells affect the development and progression of hepatocarcinogenesis N Kobayashi, N Hiraoka, W Yamagami, H Ojima, Y Kanai, T Kosuge, ... Clinical Cancer Research 13 (3), 902-911, 2007 | 522 | 2007 |
| E-cadherin gene mutations in human gastric carcinoma cell lines. T Oda, Y Kanai, T Oyama, K Yoshiura, Y Shimoyama, W Birchmeier, ... Proceedings of the National Academy of Sciences 91 (5), 1858-1862, 1994 | 407 | 1994 |
| A truncated β-catenin disrupts the interaction between E-cadherin and α-catenin: a cause of loss of intercellular adhesiveness in human cancer cell lines T Oyama, Y Kanai, A Ochiai, S Akimoto, T Oda, K Yanagihara, ... Cancer Research 54 (23), 6282-6287, 1994 | 394 | 1994 |
| Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG … T Etoh, Y Kanai, S Ushijima, T Nakagawa, Y Nakanishi, M Sasako, ... The American journal of pathology 164 (2), 689-699, 2004 | 386 | 2004 |
| The E‐cadherin gene is silenced by CpG methylation in human hepatocellular carcinomas Y Kanai, S Ushijima, AM Hui, A Ochiai, H Tsuda, M Sakamoto, ... International journal of cancer 71 (3), 355-359, 1997 | 333 | 1997 |
| Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas Y Saito, Y Kanai, T Nakagawa, M Sakamoto, H Saito, H Ishii, S Hirohashi International journal of cancer 105 (4), 527-532, 2003 | 317 | 2003 |
| Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis—a comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci … Y Kondo, Y Kanai, M Sakamoto, M Mizokami, R Ueda, S Hirohashi Hepatology 32 (5), 970-979, 2000 | 315 | 2000 |
| Expression of mRNA for DNA methyltransferases and methyl-CpG–binding proteins and DNA methylation status on CpG islands and pericentromeric satellite regions during human … Y Saito, Y Kanai, M Sakamoto, H Saito, H Ishii, S Hirohashi Hepatology 33 (3), 561-568, 2001 | 313 | 2001 |
| Intratumoral tertiary lymphoid organ is a favourable prognosticator in patients with pancreatic cancer N Hiraoka, Y Ino, R Yamazaki-Itoh, Y Kanai, T Kosuge, K Shimada British journal of cancer 112 (11), 1782-1790, 2015 | 309 | 2015 |
| MicroRNA-500 as a potential diagnostic marker for hepatocellular carcinoma Y Yamamoto, N Kosaka, M Tanaka, F Koizumi, Y Kanai, T Mizutani, ... Biomarkers 14 (7), 529-538, 2009 | 308 | 2009 |
| Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis Y Saito, Y Kanai, M Sakamoto, H Saito, H Ishii, S Hirohashi Proceedings of the National Academy of Sciences 99 (15), 10060-10065, 2002 | 274 | 2002 |
| DNA methyltransferase expression and DNA methylation of CPG islands and peri‐centromeric satellite regions in human colorectal and stomach cancers Y Kanai, S Ushijima, Y Kondo, Y Nakanishi, S Hirohashi International journal of cancer 91 (2), 205-212, 2001 | 273 | 2001 |
| Alterations of DNA methylation associated with abnormalities of DNA methyltransferases in human cancers during transition from a precancerous to a malignant state Y Kanai, S Hirohashi Carcinogenesis 28 (12), 2434-2442, 2007 | 265 | 2007 |
| Downregulation and growth inhibitory effect of epithelial-type Krüppel-like transcription factor KLF4, but not KLF5, in bladder cancer S Ohnishi, S Ohnami, F Laub, K Aoki, K Suzuki, Y Kanai, K Haga, ... Biochemical and biophysical research communications 308 (2), 251-256, 2003 | 253 | 2003 |
| Prognostic significance of tissue factor in pancreatic ductal adenocarcinoma N Nitori, Y Ino, Y Nakanishi, T Yamada, K Honda, K Yanagihara, ... Clinical cancer research 11 (7), 2531-2539, 2005 | 229 | 2005 |
| Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells Y Saito, H Suzuki, H Tsugawa, I Nakagawa, J Matsuzaki, Y Kanai, T Hibi Oncogene 28 (30), 2738-2744, 2009 | 228 | 2009 |
Eri AraiDepartment of Pathology, Keio University School of MedicineEmail verificata su keio.jp
