| KRAS: feeding pancreatic cancer proliferation KL Bryant, JD Mancias, AC Kimmelman, CJ Der Trends in biochemical sciences 39 (2), 91-100, 2014 | 800 | 2014 |
| Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer KL Bryant, CA Stalnecker, D Zeitouni, JE Klomp, S Peng, AP Tikunov, ... Nature medicine 25 (4), 628-640, 2019 | 610 | 2019 |
| Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells MA Antonyak, B Li, LK Boroughs, JL Johnson, JE Druso, KL Bryant, ... Proceedings of the National Academy of Sciences 108 (12), 4852-4857, 2011 | 575 | 2011 |
| KRAS mutant pancreatic cancer: no lone path to an effective treatment D Zeitouni, Y Pylayeva-Gupta, CJ Der, KL Bryant Cancers 8 (4), 45, 2016 | 248 | 2016 |
| Long-term ERK inhibition in KRAS-mutant pancreatic cancer is associated with MYC degradation and senescence-like growth suppression TK Hayes, NF Neel, C Hu, P Gautam, M Chenard, B Long, M Aziz, ... Cancer cell 29 (1), 75-89, 2016 | 248 | 2016 |
| Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer GA Hobbs, NM Baker, AM Miermont, RD Thurman, M Pierobon, TH Tran, ... Cancer discovery 10 (1), 104-123, 2020 | 176 | 2020 |
| KRAS suppression-induced degradation of MYC is antagonized by a MEK5-ERK5 compensatory mechanism AV Vaseva, DR Blake, TSK Gilbert, S Ng, G Hostetter, SH Azam, ... Cancer cell 34 (5), 807-822. e7, 2018 | 164 | 2018 |
| Combination Therapies with CDK4/6 Inhibitors to Treat KRAS-Mutant Pancreatic Cancer CM Goodwin, AM Waters, JE Klomp, S Javaid, KL Bryant, CA Stalnecker, ... Cancer research 83 (1), 141-157, 2023 | 72 | 2023 |
| The sustained induction of c-MYC drives nab-paclitaxel resistance in primary pancreatic ductal carcinoma cells E Parasido, GS Avetian, A Naeem, G Graham, M Pishvaian, E Glasgow, ... Molecular Cancer Research 17 (9), 1815-1827, 2019 | 54 | 2019 |
| Concurrent inhibition of IGF1R and ERK increases pancreatic cancer sensitivity to autophagy inhibitors CA Stalnecker, KR Grover, AC Edwards, MF Coleman, R Yang, ... Cancer research 82 (4), 586-598, 2022 | 40 | 2022 |
| KRAS-dependent cancer cells promote survival by producing exosomes enriched in Survivin WH Chang, TTT Nguyen, CH Hsu, KL Bryant, HJ Kim, H Ying, ... Cancer letters 517, 66-77, 2021 | 35 | 2021 |
| Spatially defined EGF receptor activation reveals an F-actin-dependent phospho-Erk signaling complex A Singhai, DL Wakefield, KL Bryant, SR Hammes, D Holowka, B Baird Biophysical journal 107 (11), 2639-2651, 2014 | 29 | 2014 |
| Polyunsaturated fatty acids inhibit stimulated coupling between the ER Ca2+ sensor STIM1 and the Ca2+ channel protein Orai1 in a process that correlates with inhibition of … D Holowka, MK Korzeniowski, KL Bryant, B Baird Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014 | 26 | 2014 |
| CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment JE Klomp, YS Lee, CM Goodwin, B Papke, JA Klomp, AM Waters, ... Cell reports 37 (9), 2021 | 24 | 2021 |
| Blocking autophagy to starve pancreatic cancer KL Bryant, CJ Der Nature reviews Molecular cell biology 20 (5), 265-265, 2019 | 22 | 2019 |
| Oncogenic RAS promotes MYC protein stability by upregulating the expression of the inhibitor of apoptosis protein family member Survivin WH Chang, Y Liu, EA Hammes, KL Bryant, RA Cerione, MA Antonyak Journal of Biological Chemistry 299 (2), 2023 | 15 | 2023 |
| Genome-wide DNA methylation analysis of KRAS mutant cell lines BY Tew, JK Durand, KL Bryant, TK Hayes, S Peng, NL Tran, GC Gooden, ... Scientific reports 10 (1), 10149, 2020 | 13 | 2020 |
| Defining the KRAS-and ERK-dependent transcriptome in KRAS-mutant cancers JA Klomp, JE Klomp, CA Stalnecker, KL Bryant, AC Edwards, ... Science 384 (6700), eadk0775, 2024 | 12 | 2024 |
| Determining the ERK-regulated phosphoproteome driving KRAS-mutant cancer JE Klomp, JN Diehl, JA Klomp, AC Edwards, R Yang, AJ Morales, ... Science 384 (6700), eadk0850, 2024 | 11 | 2024 |
| Mutations in the polybasic juxtamembrane sequence of both plasma membrane-and endoplasmic reticulum-localized epidermal growth factor receptors confer ligand-independent cell … KL Bryant, MA Antonyak, RA Cerione, B Baird, D Holowka Journal of Biological Chemistry 288 (48), 34930-34942, 2013 | 11 | 2013 |
