| Asparagine bioavailability governs metastasis in a model of breast cancer SRV Knott, E Wagenblast, S Khan, SY Kim, M Soto, M Wagner, ... Nature 554 (7692), 378-381, 2018 | 494 | 2018 |
| A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis E Wagenblast, M Soto, S Gutiérrez-Ángel, CA Hartl, AL Gable, AR Maceli, ... Nature 520 (7547), 358-362, 2015 | 439 | 2015 |
| Lessons in estrogen biology from knockout and transgenic animals SC Hewitt, JC Harrell, KS Korach Annu. Rev. Physiol. 67, 285-308, 2005 | 389 | 2005 |
| The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-β signaling DS Micalizzi, KL Christensen, P Jedlicka, RD Coletta, AE Barón, ... The Journal of clinical investigation 119 (9), 2678-2690, 2009 | 284 | 2009 |
| Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse JC Harrell, A Prat, JS Parker, C Fan, X He, L Carey, C Anders, M Ewend, ... Breast cancer research and treatment 132, 523-535, 2012 | 272 | 2012 |
| Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes A Prat, O Karginova, JS Parker, C Fan, X He, L Bixby, JC Harrell, ... Breast cancer research and treatment 142, 237-255, 2013 | 254 | 2013 |
| Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts AD Pfefferle, JI Herschkowitz, J Usary, JC Harrell, BT Spike, JR Adams, ... Genome biology 14, 1-16, 2013 | 252 | 2013 |
| Taxonomy of breast cancer based on normal cell phenotype predicts outcome S Santagata, A Thakkar, A Ergonul, B Wang, T Woo, R Hu, JC Harrell, ... The Journal of clinical investigation 124 (2), 859-870, 2014 | 236 | 2014 |
| Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours TA Ince, AD Sousa, MA Jones, JC Harrell, ES Agoston, M Krohn, ... Nature communications 6 (1), 7419, 2015 | 214 | 2015 |
| Estrogen receptor positive breast cancer metastasis: altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes JC Harrell, WW Dye, DC Allred, P Jedlicka, NS Spoelstra, CA Sartorius, ... Cancer research 66 (18), 9308-9315, 2006 | 177 | 2006 |
| Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts KB Horwitz, WW Dye, JC Harrell, P Kabos, CA Sartorius Proceedings of the National Academy of Sciences 105 (15), 5774-5779, 2008 | 165 | 2008 |
| Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures P Kabos, J Finlay-Schultz, C Li, E Kline, C Finlayson, J Wisell, CA Manuel, ... Breast cancer research and treatment 135, 415-432, 2012 | 159 | 2012 |
| SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer CA Wang, P Jedlicka, AN Patrick, DS Micalizzi, KC Lemmer, E Deitsch, ... The Journal of clinical investigation 122 (5), 1895-1906, 2012 | 154 | 2012 |
| Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch JM Haughian, MP Pinto, JC Harrell, BS Bliesner, KM Joensuu, WW Dye, ... Proceedings of the National Academy of Sciences 109 (8), 2742-2747, 2012 | 133 | 2012 |
| Interactions with fibroblasts are distinct in Basal-like and luminal breast cancers JT Camp, F Elloumi, E Roman-Perez, J Rein, DA Stewart, JC Harrell, ... Molecular Cancer Research 9 (1), 3-13, 2011 | 126 | 2011 |
| Sox10 regulates stem/progenitor and mesenchymal cell states in mammary epithelial cells C Dravis, BT Spike, JC Harrell, C Johns, CL Trejo, EM Southard-Smith, ... Cell reports 12 (12), 2035-2048, 2015 | 125 | 2015 |
| Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases B Adamo, AM Deal, E Burrows, J Geradts, E Hamilton, KL Blackwell, ... Breast cancer research 13, 1-11, 2011 | 117 | 2011 |
| Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and … R Iwanaga, CA Wang, DS Micalizzi, JC Harrell, P Jedlicka, CA Sartorius, ... Breast Cancer Research 14, 1-14, 2012 | 112 | 2012 |
| Update on animal models developed for analyses of estrogen receptor biological activity KS Korach, JMA Emmen, VR Walker, SC Hewitt, M Yates, JM Hall, ... The Journal of Steroid Biochemistry and Molecular Biology 86 (3-5), 387-391, 2003 | 111 | 2003 |
| Spontaneous fusion with, and transformation of mouse stroma by, malignant human breast cancer epithelium BM Jacobsen, JC Harrell, P Jedlicka, VF Borges, M Varella-Garcia, ... Cancer research 66 (16), 8274-8279, 2006 | 104 | 2006 |