The chaperone activity of 4PBA ameliorates the skeletal phenotype of Chihuahua, a zebrafish model for dominant osteogenesis imperfecta R Gioia, F Tonelli, I Ceppi, M Biggiogera, S Leikin, S Fisher, E Tenedini, ... Human molecular genetics 26 (15), 2897-2911, 2017 | 76 | 2017 |
CtIP promotes the motor activity of DNA2 to accelerate long-range DNA end resection I Ceppi, SM Howard, K Kasaciunaite, C Pinto, R Anand, R Seidel, P Cejka Proceedings of the National Academy of Sciences 117 (16), 8859-8869, 2020 | 70 | 2020 |
Double-stranded DNA binding function of RAD51 in DNA protection and its regulation by BRCA2 S Halder, A Sanchez, L Ranjha, G Reginato, I Ceppi, A Acharya, R Anand, ... Molecular Cell 82 (19), 3553-3565. e5, 2022 | 37 | 2022 |
Phosphorylation of the RecQ helicase Sgs1/BLM controls its DNA unwinding activity during meiosis and mitosis R Grigaitis, L Ranjha, P Wild, K Kasaciunaite, I Ceppi, V Kissling, ... Developmental cell 53 (6), 706-723. e5, 2020 | 37 | 2020 |
Phosphorylated CtIP bridges DNA to promote annealing of broken ends R Öz, SM Howard, R Sharma, H Törnkvist, I Ceppi, S Kk, E Kristiansson, ... Proceedings of the National Academy of Sciences 117 (35), 21403-21412, 2020 | 35 | 2020 |
MRNIP is a replication fork protection factor LG Bennett, AM Wilkie, E Antonopoulou, I Ceppi, A Sanchez, EG Vernon, ... Science advances 6 (28), eaba5974, 2020 | 21 | 2020 |
The iron–sulphur cluster in human DNA2 is required for all biochemical activities of DNA2 L Mariotti, S Wild, G Brunoldi, A Piceni, I Ceppi, S Kummer, RE Lutz, ... Communications biology 3 (1), 322, 2020 | 18 | 2020 |
WRN helicase and mismatch repair complexes independently and synergistically disrupt cruciform DNA structures V Mengoli, I Ceppi, A Sanchez, E Cannavo, S Halder, S Scaglione, ... The EMBO Journal 42 (3), e111998, 2023 | 16 | 2023 |
The CDK1-TOPBP1-PLK1 axis regulates the Bloom’s syndrome helicase BLM to suppress crossover recombination in somatic cells C Balbo Pogliano, I Ceppi, S Giovannini, V Petroulaki, N Palmer, F Uliana, ... Science Advances 8 (5), eabk0221, 2022 | 16 | 2022 |
The internal region of CtIP negatively regulates DNA end resection SM Howard, I Ceppi, R Anand, R Geiger, P Cejka Nucleic acids research 48 (10), 5485-5498, 2020 | 15 | 2020 |
PLK1 regulates CtIP and DNA2 interplay in long-range DNA end resection I Ceppi, E Cannavo, H Bret, R Camarillo, F Vivalda, RS Thakur, ... Genes & development 37 (3-4), 119-135, 2023 | 11 | 2023 |
A disease-causing single amino acid deletion in the coiled-coil domain of RAD50 impairs MRE11 complex functions in yeast and humans M Chansel-Da Cruz, M Hohl, I Ceppi, L Kermasson, L Maggiorella, ... Cell Reports 33 (13), 2020 | 11 | 2020 |
HLTF disrupts Cas9-DNA post-cleavage complexes to allow DNA break processing G Reginato, MR Dello Stritto, Y Wang, J Hao, R Pavani, M Schmitz, ... Nature Communications 15 (1), 5789, 2024 | 6 | 2024 |
Mechanism of BRCA1–BARD1 function in DNA end resection and DNA protection I Ceppi, MR Dello Stritto, M Mütze, S Braunshier, V Mengoli, G Reginato, ... Nature, 1-9, 2024 | 5 | 2024 |
Xrs2/NBS1 promote end-bridging activity of the MRE11-RAD50 complex C Möller, R Sharma, R Öz, G Reginato, E Cannavo, I Ceppi, KK Sriram, ... Biochemical and Biophysical Research Communications 695, 149464, 2024 | 3 | 2024 |
Tumor-associated neutrophil precursors impair homologous DNA repair and promote sensitivity to PARP-inhibition A Calcinotto, S Mukherjee, A Elia, C Garda, L Boffa, MT Balia, M Bolis, ... | | 2024 |
Tumor-associated neutrophil precursors impair homologous DNA repair and promote sensitivity to PARP-inhibition S Mukherjee, A Elia, C Garda, L Boffa, MT Balia, M Bolis, S Mosole, ... Institute of Oncology Research David Jarrossay Institute for Research in …, 2024 | | 2024 |
Nanofluidics highlights importance of CtIP's tetrameric structure for DNA repair C Möller, KK Sriram, I Ceppi, P Cejka, F Westerlund Biophysical Journal 123 (3), 148a, 2024 | | 2024 |
Mechanism of BRCA1-BARD1 function in DNA end resection and DNA protection P Cejka, I Ceppi, MRD Stritto, S Braunshier, M Mutze, G Reginato, ... | | 2024 |
The PIN1-p38-CtIP signaling axis protects stalled replication forks from deleterious degradation AA Sartori, F Vivalda, M Gatti, L Manfredi, H Dogan, A Porro, G Collotta, ... bioRxiv, 2024.06. 25.600562, 2024 | | 2024 |