FUS phase separation is modulated by a molecular chaperone and methylation of arginine cation-π interactions S Qamar*, GZ Wang*, SJ Randle*, FS Ruggeri*, JA Varela*, JQ Lin*, ... Cell 173 (3), 720-734. e15, 2018 | 828 | 2018 |
Effects of transport inhibitors on the cellular uptake of carboxylated polystyrene nanoparticles in different cell lines T Dos Santos, J Varela, I Lynch, A Salvati, KA Dawson PloS one 6 (9), e24438, 2011 | 509 | 2011 |
Experimental and theoretical comparison of intracellular import of polymeric nanoparticles and small molecules: toward models of uptake kinetics A Salvati, C Åberg, T dos Santos, J Varela, P Pinto, I Lynch, KA Dawson Nanomedicine: Nanotechnology, Biology and Medicine 7 (6), 818-826, 2011 | 358 | 2011 |
Quantitative assessment of the comparative nanoparticle‐uptake efficiency of a range of cell lines T Dos Santos, J Varela, I Lynch, A Salvati, KA Dawson Small 7 (23), 3341-3349, 2011 | 306 | 2011 |
Surface diffusion of astrocytic glutamate transporters shapes synaptic transmission C Murphy-Royal, JP Dupuis, JA Varela, A Panatier, B Pinson, J Baufreton, ... Nature neuroscience 18 (2), 219-226, 2015 | 284 | 2015 |
Single-nanotube tracking reveals the nanoscale organization of the extracellular space in the live brain AG Godin*, JA Varela*, Z Gao*, N Danné, JP Dupuis, B Lounis, L Groc, ... Nature nanotechnology 12 (3), 238-243, 2017 | 253 | 2017 |
Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms S De, DC Wirthensohn, P Flagmeier, C Hughes, FA Aprile, FS Ruggeri, ... Nature communications 10 (1), 1541, 2019 | 187 | 2019 |
Quantifying size-dependent interactions between fluorescently labeled polystyrene nanoparticles and mammalian cells JA Varela, MG Bexiga, C Åberg, JC Simpson, KA Dawson Journal of nanobiotechnology 10, 1-6, 2012 | 169 | 2012 |
Cationic nanoparticles induce caspase 3-, 7-and 9-mediated cytotoxicity in a human astrocytoma cell line MG Bexiga, JA Varela, F Wang, F Fenaroli, A Salvati, I Lynch, JC Simpson, ... Nanotoxicology 5 (4), 557-567, 2011 | 147 | 2011 |
Surface dynamics of G lu N 2 B‐NMDA receptors controls plasticity of maturing glutamate synapses JP Dupuis, L Ladépêche, H Seth, L Bard, J Varela, L Mikasova, ... The EMBO journal 33 (8), 842-861, 2014 | 144 | 2014 |
Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices JA Varela, JP Dupuis, L Etchepare, A Espana, L Cognet, L Groc Nature communications 7 (1), 10947, 2016 | 85 | 2016 |
Hyper-bright Near-Infrared Emitting Fluorescent Organic Nanoparticles for Single Particle Tracking E Genin, Z Gao, JA Varela, J Daniel, T Bsaibess, I Gosse, L Groc, ... Advanced Materials 26 (14), 2258-2261, 2014 | 74 | 2014 |
ThX–a next-generation probe for the early detection of amyloid aggregates LM Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, ... Chemical Science 11 (18), 4578-4583, 2020 | 60 | 2020 |
Toward the suppression of cellular toxicity from single-walled carbon nanotubes Z Gao, JA Varela, L Groc, B Lounis, L Cognet Biomaterials science 4 (2), 230-244, 2016 | 52 | 2016 |
Optical Structural Analysis of Individual α‐Synuclein Oligomers JA Varela, M Rodrigues, S De, P Flagmeier, S Gandhi, CM Dobson, ... Angewandte Chemie 130 (18), 4980-4984, 2018 | 47 | 2018 |
Comparative analysis of photoluminescence and upconversion emission from individual carbon nanotubes for bioimaging applications N Danné, AG Godin, Z Gao, JA Varela, L Groc, B Lounis, L Cognet ACS photonics 5 (2), 359-364, 2018 | 36 | 2018 |
Single nanoparticle tracking of N-methyl-D-aspartate receptors in cultured and intact brain tissue JA Varela*, JS Ferreira*, JP Dupuis*, P Durand, D Bouchet, L Groc Neurophotonics 3 (4), 041808-041808, 2016 | 24 | 2016 |
Trajectory‐Based Co‐Localization Measures for Nanoparticle‐Cell Interaction Studies JA Varela, C Åberg, JC Simpson, KA Dawson Small 11 (17), 2026-2031, 2015 | 17 | 2015 |
Structure-specific amyloid precipitation in biofluids M Rodrigues, P Bhattacharjee, A Brinkmalm, DT Do, CM Pearson, S De, ... Nature Chemistry 14 (9), 1045-1053, 2022 | 16 | 2022 |
Spatial and structural metrics for living cells inspired by statistical mechanics C Åberg*, JA Varela*, LW Fitzpatrick, KA Dawson Scientific reports 6 (1), 34457, 2016 | 16 | 2016 |