Articoli con mandati relativi all'accesso pubblico - Amanda J KedaigleUlteriori informazioni
Disponibili pubblicamente: 21
MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L
KM Bernt, N Zhu, AU Sinha, S Vempati, J Faber, AV Krivtsov, Z Feng, ...
Cancer cell 20 (1), 66-78, 2011
Mandati: US National Institutes of Health, German Research Foundation
Individual brain organoids reproducibly form cell diversity of the human cerebral cortex
S Velasco, AJ Kedaigle, SK Simmons, A Nash, M Rocha, G Quadrato, ...
Nature 570 (7762), 523-527, 2019
Mandati: US National Institutes of Health, Howard Hughes Medical Institute
Systematic comparison of single-cell and single-nucleus RNA-sequencing methods
J Ding, X Adiconis, SK Simmons, MS Kowalczyk, CC Hession, ...
Nature biotechnology 38 (6), 737-746, 2020
Mandati: US National Institutes of Health, Howard Hughes Medical Institute
Autism genes converge on asynchronous development of shared neuron classes
B Paulsen, S Velasco, AJ Kedaigle, M Pigoni, G Quadrato, AJ Deo, ...
Nature 602 (7896), 268-273, 2022
Mandati: US National Institutes of Health, Howard Hughes Medical Institute
Huntington’s disease iPSC-derived brain microvascular endothelial cells reveal WNT-mediated angiogenic and blood-brain barrier deficits
RG Lim, C Quan, AM Reyes-Ortiz, SE Lutz, AJ Kedaigle, TA Gipson, J Wu, ...
Cell reports 19 (7), 1365-1377, 2017
Mandati: US National Science Foundation, US National Institutes of Health, American …
Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice
Nature neuroscience 20 (5), 648-660, 2017
Mandati: US National Science Foundation, US National Institutes of Health, American …
Network-based interpretation of diverse high-throughput datasets through the omics integrator software package
N Tuncbag, SJC Gosline, A Kedaigle, AR Soltis, A Gitter, E Fraenkel
PLoS computational biology 12 (4), e1004879, 2016
Mandati: US National Science Foundation, US National Institutes of Health
Skin-resident innate lymphoid cells converge on a pathogenic effector state
P Bielecki, SJ Riesenfeld, JC Hütter, E Torlai Triglia, MS Kowalczyk, ...
Nature 592 (7852), 128-132, 2021
Mandati: US National Institutes of Health, Howard Hughes Medical Institute, German …
Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex
A Uzquiano, AJ Kedaigle, M Pigoni, B Paulsen, X Adiconis, K Kim, T Faits, ...
Cell 185 (20), 3770-3788. e27, 2022
Mandati: US National Institutes of Health, Howard Hughes Medical Institute, Chan …
Systematic comparative analysis of single cell RNA-sequencing methods
J Ding, X Adiconis, SK Simmons, MS Kowalczyk, CC Hession, ...
BioRxiv, 632216, 2019
Mandati: Howard Hughes Medical Institute
Individual oligodendrocytes show bias for inhibitory axons in the neocortex
M Zonouzi, D Berger, V Jokhi, A Kedaigle, J Lichtman, P Arlotta
Cell Reports 27 (10), 2799-2808. e3, 2019
Mandati: US Department of Defense, US National Institutes of Health, US Office of the …
PCSF: An R-package for network-based interpretation of high-throughput data
M Akhmedov, A Kedaigle, RE Chong, R Montemanni, F Bertoni, ...
PLoS computational biology 13 (7), e1005694, 2017
Mandati: Swiss National Science Foundation, US National Institutes of Health
Bioenergetic deficits in Huntington’s disease iPSC-derived neural cells and rescue with glycolytic metabolites
Human molecular genetics 29 (11), 1757-1771, 2020
Mandati: US National Science Foundation, US National Institutes of Health, American …
Single-cell multiomics atlas of organoid development uncovers longitudinal molecular programs of cellular diversification of the human cerebral cortex
A Uzquiano, AJ Kedaigle, M Pigoni, B Paulsen, X Adiconis, K Kim, T Faits, ...
BioRxiv, 2022.03. 17.484798, 2022
Mandati: US National Institutes of Health, Howard Hughes Medical Institute
Discovering altered regulation and signaling through network-based integration of transcriptomic, epigenomic, and proteomic tumor data
AJ Kedaigle, E Fraenkel
Cancer Systems Biology: Methods and Protocols, 13-26, 2018
Mandati: US National Institutes of Health
Treatment with JQ1, a BET bromodomain inhibitor, is selectively detrimental to R6/2 Huntington’s disease mice
AJ Kedaigle, JC Reidling, RG Lim, M Adam, J Wu, B Wassie, ...
Human Molecular Genetics 29 (2), 202-215, 2020
Mandati: US National Science Foundation, US National Institutes of Health
Human brain organoids reveal accelerated development of cortical neuron classes as a shared feature of autism risk genes
B Paulsen, S Velasco, AJ Kedaigle, M Pigoni, G Quadrato, A Deo, ...
BioRxiv, 2020.11. 10.376509, 2020
Mandati: US National Institutes of Health, Howard Hughes Medical Institute
Turning omics data into therapeutic insights
A Kedaigle, E Fraenkel
Current opinion in pharmacology 42, 95-101, 2018
Mandati: US National Institutes of Health
Immortalized striatal precursor neurons from Huntington’s disease patient-derived iPS cells as a platform for target identification and screening for experimental therapeutics
SS Akimov, M Jiang, AJ Kedaigle, N Arbez, LO Marque, CR Eddings, ...
Human molecular genetics 30 (24), 2469-2487, 2021
Mandati: US National Institutes of Health
Cell-type specific defects in PTEN-mutant cortical organoids converge on abnormal circuit activity
M Pigoni, A Uzquiano, B Paulsen, AJ Kedaigle, SM Yang, P Symvoulidis, ...
Human Molecular Genetics 32 (18), 2773-2786, 2023
Mandati: US National Institutes of Health, Howard Hughes Medical Institute, Chan …
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