ErbB receptors: from oncogenes to targeted cancer therapies H Zhang, A Berezov, Q Wang, G Zhang, J Drebin, R Murali, MI Greene Journal of Clinical Investigation 117 (8), 2051, 2007 | 805 | 2007 |
Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis J Xue, V Sharma, MH Hsieh, A Chawla, R Murali, SJ Pandol, A Habtezion Nature communications 6 (1), 7158, 2015 | 366 | 2015 |
HER2/Neu: mechanisms of dimerization/oligomerization. PJ Brennan, T Kumagai, A Berezov, R Murali, MI Greene Oncogene 19 (53), 6093, 2000 | 290 | 2000 |
Rationally designed anti-HER2/neu peptide mimetic disables P185HER2/neu tyrosine kinases in vitro and in vivo BW Park, HT Zhang, C Wu, A Berezov, X Zhang, R Dua, Q Wang, G Kao, ... Nature biotechnology 18 (2), 194-198, 2000 | 271 | 2000 |
Polymersomes: A new multi-functional tool for cancer diagnosis and therapy DH Levine, PP Ghoroghchian, J Freudenberg, G Zhang, MJ Therien, ... Methods 46 (1), 25-32, 2008 | 262 | 2008 |
Structure–based design and characterization of exocyclic peptidomimetics that inhibit TNFα binding to its receptor W Takasaki, Y Kajino, K Kajino, R Murali, MI Greene Nature biotechnology 15 (12), 1266-1270, 1997 | 181 | 1997 |
The refined crystal structure of hexon, the major coat protein of adenovirus type 2, at 2· 9 Å resolution FK Athappily, R Murali, JJ Rux, Z Cai, RM Burnett Journal of molecular biology 242 (4), 430-455, 1994 | 175 | 1994 |
Role of tryptophan repeats and flanking amino acids in Myb-DNA interactions P Saikumar, R Murali, EP Reddy Proceedings of the National Academy of Sciences 87 (21), 8452-8456, 1990 | 168 | 1990 |
A TNF receptor loop peptide mimic blocks RANK ligand-induced signaling, bone resorption, and bone loss K Aoki, H Saito, C Itzstein, M Ishiguro, T Shibata, R Blanque, AH Mian, ... Journal of Clinical Investigation 116 (6), 1525, 2006 | 165 | 2006 |
ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis M Rotinen, S You, J Yang, SG Coetzee, M Reis-Sobreiro, WC Huang, ... Nature medicine 24 (12), 1887-1898, 2018 | 160 | 2018 |
Stearoyl-CoA desaturase promotes liver fibrosis and tumor development in mice via a Wnt positive-signaling loop by stabilization of low-density lipoprotein-receptor-related … KKY Lai, SM Kweon, F Chi, E Hwang, Y Kabe, R Higashiyama, L Qin, ... Gastroenterology 152 (6), 1477-1491, 2017 | 158 | 2017 |
Structure of Sad1-UNC84 homology (SUN) domain defines features of molecular bridge in nuclear envelope Z Zhou, X Du, Z Cai, X Song, H Zhang, T Mizuno, E Suzuki, MR Yee, ... Journal of Biological Chemistry 287 (8), 5317-5326, 2012 | 154 | 2012 |
Therapeutic peptides and peptidomimetics T Kieber-Emmons, R Murali, MI Greene Current opinion in biotechnology 8 (4), 435-441, 1997 | 150 | 1997 |
Disabling erbB receptors with rationally designed exocyclic mimetics of antibodies: Structure− function analysis A Berezov, HT Zhang, MI Greene, R Murali Journal of medicinal chemistry 44 (16), 2565-2574, 2001 | 132 | 2001 |
Arginine at positions 13 or 70-71 in pocket 4 of HLA-DRB1 alleles is associated with susceptibility to tuberculoid leprosy. L Zerva, B Cizman, NK Mehra, SK Alahari, R Murali, CM Zmijewski, ... The Journal of experimental medicine 183 (3), 829-836, 1996 | 124 | 1996 |
Disabling receptor ensembles with rationally designed interface peptidomimetics A Berezov, J Chen, Q Liu, HT Zhang, MI Greene, R Murali Journal of Biological Chemistry 277 (31), 28330-28339, 2002 | 118 | 2002 |
Acute pesticide poisoning: 15 years experience of a large North-West Indian hospital R Murali, A Bhalla, D Singh, S Singh Clinical toxicology 47 (1), 35-38, 2009 | 109 | 2009 |
Group B Streptococcus evades host immunity by degrading hyaluronan SL Kolar, P Kyme, CW Tseng, A Soliman, A Kaplan, J Liang, V Nizet, ... Cell host & microbe 18 (6), 694-704, 2015 | 104 | 2015 |
Disabling of receptor activator of nuclear factor-κB (RANK) receptor complex by novel osteoprotegerin-like peptidomimetics restores bone loss in vivo X Cheng, M Kinosaki, M Takami, Y Choi, H Zhang, R Murali Journal of Biological Chemistry 279 (9), 8269-8277, 2004 | 101 | 2004 |
Mutagenesis of the putative alpha-helical domain of the Vpr protein of human immunodeficiency virus type 1: effect on stability and virion incorporation. S Mahalingam, SA Khan, R Murali, MA Jabbar, CE Monken, RG Collman, ... Proceedings of the National Academy of Sciences 92 (9), 3794-3798, 1995 | 97 | 1995 |