Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export P Lei, S Ayton, DI Finkelstein, L Spoerri, GD Ciccotosto, DK Wright, ... Nature medicine 18 (2), 291-295, 2012 | 650 | 2012 |
Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease S Ayton, P Lei, JA Duce, BXW Wong, A Sedjahtera, PA Adlard, AI Bush, ... Annals of neurology 73 (4), 554-559, 2013 | 281 | 2013 |
β-Amyloid precursor protein does not possess ferroxidase activity but does stabilize the cell surface ferrous iron exporter ferroportin BX Wong, A Tsatsanis, LQ Lim, PA Adlard, AI Bush, JA Duce PloS one 9 (12), e114174, 2014 | 160 | 2014 |
Amyloid-β peptide Aβ3pE-42 induces lipid peroxidation, membrane permeabilization, and calcium influx in neurons AP Gunn, BX Wong, T Johanssen, JC Griffith, CL Masters, AI Bush, ... Journal of Biological Chemistry 291 (12), 6134-6145, 2016 | 98 | 2016 |
Post translational changes to α-synuclein control iron and dopamine trafficking; a concept for neuron vulnerability in Parkinson’s disease JA Duce, BX Wong, H Durham, JC Devedjian, DP Smith, D Devos Molecular neurodegeneration 12, 1-12, 2017 | 76 | 2017 |
Amyloidogenic processing of Alzheimer’s disease β-amyloid precursor protein induces cellular iron retention A Tsatsanis, BX Wong, AP Gunn, S Ayton, AI Bush, D Devos, JA Duce Molecular psychiatry 25 (9), 1958-1966, 2020 | 65 | 2020 |
Marked age-related changes in brain iron homeostasis in amyloid protein precursor knockout mice AA Belaidi, AP Gunn, BX Wong, S Ayton, AT Appukuttan, BR Roberts, ... Neurotherapeutics 15, 1055-1062, 2018 | 65 | 2018 |
The iron regulatory capability of the major protein participants in prevalent neurodegenerative disorders BX Wong, JA Duce Frontiers in pharmacology 5, 81, 2014 | 55 | 2014 |
Metals and cholesterol: two sides of the same coin in Alzheimer’s disease pathology BX Wong, YH Hung, AI Bush, JA Duce Frontiers in Aging Neuroscience 6, 91, 2014 | 50 | 2014 |
Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta MIG Lopez Sanchez, HS Waugh, A Tsatsanis, BX Wong, JG Crowston, ... Scientific reports 7 (1), 9835, 2017 | 46 | 2017 |
The acute phase protein lactoferrin is a key feature of Alzheimer’s disease and predictor of Aβ burden through induction of APP amyloidogenic processing A Tsatsanis, AN McCorkindale, BX Wong, E Patrick, TM Ryan, RW Evans, ... Molecular psychiatry 26 (10), 5516-5531, 2021 | 40 | 2021 |
Post translational modulation of β-amyloid precursor protein trafficking to the cell surface alters neuronal iron homeostasis A Tsatsanis, S Dickens, JCF Kwok, BX Wong, JA Duce Neurochemical Research 44, 1367-1374, 2019 | 39 | 2019 |
P2X7 receptor-mediated scavenger activity of mononuclear phagocytes toward non-opsonized particles and apoptotic cells is inhibited by serum glycoproteins but remains active in … BJ Gu, JA Duce, VA Valova, B Wong, AI Bush, S Petrou, JS Wiley Journal of Biological Chemistry 287 (21), 17318-17330, 2012 | 37 | 2012 |
A comparison of ceruloplasmin to biological polyanions in promoting the oxidation of Fe2+ under physiologically relevant conditions BX Wong, S Ayton, LQ Lam, P Lei, PA Adlard, AI Bush, JA Duce Biochimica et Biophysica Acta (BBA)-General Subjects 1840 (12), 3299-3310, 2014 | 34 | 2014 |
Dyslipidemic diabetic serum increases lipid accumulation and expression of stearoyl-CoA desaturase in human macrophages BXW Wong, RA Kyle, PC Myhill, KD Croft, CM Quinn, W Jessup, BB Yeap Lipids 46, 931-941, 2011 | 17 | 2011 |
Modulation of macrophage fatty acid content and composition by exposure to dyslipidemic serum in vitro BXW Wong, RA Kyle, KD Croft, CM Quinn, W Jessup, BB Yeap Lipids 46, 371-380, 2011 | 17 | 2011 |
Increased glutaminyl cyclase activity in brains of Alzheimer’s disease individuals AP Gunn, BX Wong, C McLean, C Fowler, PJ Barnard, JA Duce, ... Journal of Neurochemistry 156 (6), 979-987, 2021 | 16 | 2021 |
Oxidation of Iron under physiologically relevant conditions in biological fluids from healthy and Alzheimer’s Disease subjects LQ Lam, BX Wong, T Frugier, QX Li, SJ Collins, AI Bush, PJ Crack, ... ACS Chemical Neuroscience 8 (4), 731-736, 2017 | 3 | 2017 |
Pharmacological inhibition of STING reduces neuroinflammation‐mediated damage post‐traumatic brain injury AL Fryer, A Abdullah, F Mobilio, A Jobling, Z Moore, M de Veer, G Zheng, ... British Journal of Pharmacology, 2024 | 2 | 2024 |
Innate immune response protein lactoferrin directly binds amyloid-beta precursor protein to promote amyloidogenic processing A Tsatsanis, T Ryan, B Wong, R Evans, A Bush, J Duce JOURNAL OF NEUROCHEMISTRY 142, 66-66, 2017 | | 2017 |