HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells MR Betts, MC Nason, SM West, SC De Rosa, SA Migueles, J Abraham, ... Blood 107 (12), 4781-4789, 2006 | 2288 | 2006 |
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1 X Wu, ZY Yang, Y Li, CM Hogerkorp, WR Schief, MS Seaman, T Zhou, ... Science 329 (5993), 856-861, 2010 | 2084 | 2010 |
HIV preferentially infects HIV-specific CD4+ T cells DC Douek, JM Brenchley, MR Betts, DR Ambrozak, BJ Hill, Y Okamoto, ... Nature 417 (6884), 95-98, 2002 | 1729 | 2002 |
HLA B* 5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors SA Migueles, MS Sabbaghian, WL Shupert, MP Bettinotti, FM Marincola, ... Proceedings of the National Academy of Sciences 97 (6), 2709-2714, 2000 | 1311 | 2000 |
HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors SA Migueles, AC Laborico, WL Shupert, MS Sabbaghian, R Rabin, ... Nature immunology 3 (11), 1061-1068, 2002 | 1258 | 2002 |
Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells JM Brenchley, NJ Karandikar, MR Betts, DR Ambrozak, BJ Hill, LE Crotty, ... Blood, The Journal of the American Society of Hematology 101 (7), 2711-2720, 2003 | 1246 | 2003 |
Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals JF Scheid, H Mouquet, N Feldhahn, MS Seaman, K Velinzon, J Pietzsch, ... Nature 458 (7238), 636-640, 2009 | 1093 | 2009 |
Broad and potent neutralization of HIV-1 by a gp41-specific human antibody J Huang, G Ofek, L Laub, MK Louder, NA Doria-Rose, NS Longo, ... Nature 491 (7424), 406-412, 2012 | 1005 | 2012 |
Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing X Wu, T Zhou, J Zhu, B Zhang, I Georgiev, C Wang, X Chen, NS Longo, ... Science 333 (6049), 1593-1602, 2011 | 986 | 2011 |
HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression CJ Pitcher, C Quittner, DM Peterson, M Connors, RA Koup, VC Maino, ... Nature medicine 5 (5), 518-525, 1999 | 955 | 1999 |
Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1 MP Martin, Y Qi, X Gao, E Yamada, JN Martin, F Pereyra, S Colombo, ... Nature genetics 39 (6), 733-740, 2007 | 911 | 2007 |
Structure and immune recognition of trimeric pre-fusion HIV-1 Env M Pancera, T Zhou, A Druz, IS Georgiev, C Soto, J Gorman, J Huang, ... Nature 514 (7523), 455-461, 2014 | 857 | 2014 |
Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control SA Migueles, CM Osborne, C Royce, AA Compton, RP Joshi, KA Weeks, ... Immunity 29 (6), 1009-1021, 2008 | 671 | 2008 |
HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune … M Connors, JA Kovacs, S Krevat, JC Gea-Banacloche, MC Sneller, ... Nature medicine 3 (5), 533-540, 1997 | 638 | 1997 |
Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques T Matano, R Shibata, C Siemon, M Connors, HC Lane, MA Martin Journal of virology 72 (1), 164-169, 1998 | 627 | 1998 |
T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis JM Brenchley, BJ Hill, DR Ambrozak, DA Price, FJ Guenaga, JP Casazza, ... Journal of virology 78 (3), 1160-1168, 2004 | 522 | 2004 |
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface J Huang, BH Kang, M Pancera, JH Lee, T Tong, Y Feng, H Imamichi, ... Nature 515 (7525), 138-142, 2014 | 519 | 2014 |
Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation H Mouquet, JF Scheid, MJ Zoller, M Krogsgaard, RG Ott, S Shukair, ... Nature 467 (7315), 591-595, 2010 | 502 | 2010 |
Broad HIV-1 neutralization mediated by CD4-binding site antibodies Y Li, SA Migueles, B Welcher, K Svehla, A Phogat, MK Louder, X Wu, ... Nature medicine 13 (9), 1032-1034, 2007 | 491 | 2007 |
Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses DA Price, JM Brenchley, LE Ruff, MR Betts, BJ Hill, M Roederer, RA Koup, ... The Journal of experimental medicine 202 (10), 1349-1361, 2005 | 474 | 2005 |