| Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer’s disease DKV Kumar, SH Choi, KJ Washicosky, WA Eimer, S Tucker, J Ghofrani, ... Science translational medicine 8 (340), 340ra72-340ra72, 2016 | 1080 | 2016 |
| Utility of an improved model of amyloid-beta (Aß1-42) toxicity in Caenorhabditis elegans for drug screening for Alzheimer’s disease G McColl, BR Roberts, TL Pukala, VB Kenche, CM Roberts, CD Link, ... Molecular Neurodegeneration 7 (1), 57-57, 2012 | 268 | 2012 |
| Evolution of lifespan in C. elegans DW Walker, G McColl, NL Jenkins, J Harris, GJ Lithgow Nature 405 (6784), 296-297, 2000 | 250 | 2000 |
| Pharmacogenetic analysis of lithium-induced delayed aging in Caenorhabditis elegans G McColl, DW Killilea, AE Hubbard, MC Vantipalli, S Melov, GJ Lithgow Journal of Biological Chemistry 283 (1), 350-357, 2008 | 241 | 2008 |
| Fitness cost of extended lifespan in Caenorhabditis elegans NL Jenkins, G McColl, GJ Lithgow Proceedings of the Royal Society of London. Series B: Biological Sciences …, 2004 | 201 | 2004 |
| Imaging metals in biology: balancing sensitivity, selectivity and spatial resolution DJ Hare, EJ New, MD de Jonge, G McColl Chemical Society Reviews 44 (17), 5941-5958, 2015 | 194 | 2015 |
| Heat shock protein accumulation is upregulated in a long-lived mutant of Caenorhabditis elegans GA Walker, TM White, G McColl, NL Jenkins, S Babich, EPM Candido, ... The Journals of Gerontology Series A: Biological Sciences and Medical …, 2001 | 163 | 2001 |
| Response of Two Heat Shock Genes to Selection for Knockdown Heat Resistance in Drosophila melanogaster G McColl, AA Hoffmann, SW McKechnie Genetics 143 (4), 1615-1627, 1996 | 157 | 1996 |
| The Caenorhabditis elegans Aβ1–42 model of Alzheimer disease predominantly expresses Aβ3–42 G McColl, BR Roberts, AP Gunn, KA Perez, DJ Tew, CL Masters, ... Journal of Biological Chemistry 284 (34), 22697-22702, 2009 | 148 | 2009 |
| Life span extension via eIF4G inhibition is mediated by posttranscriptional remodeling of stress response gene expression in C. elegans AN Rogers, D Chen, G McColl, G Czerwieniec, K Felkey, BW Gibson, ... Cell metabolism 14 (1), 55-66, 2011 | 143 | 2011 |
| Insulin-like signaling determines survival during stress via posttranscriptional mechanisms in C. elegans G McColl, AN Rogers, S Alavez, AE Hubbard, S Melov, CD Link, AI Bush, ... Cell metabolism 12 (3), 260-272, 2010 | 129 | 2010 |
| Iron, copper, and zinc concentration in Aβ plaques in the APP/PS1 mouse model of Alzheimer’s disease correlates with metal levels in the surrounding neuropil SA James, QI Churches, MD de Jonge, IE Birchall, V Streltsov, G McColl, ... ACS chemical neuroscience 8 (3), 629-637, 2017 | 125 | 2017 |
| An iron–dopamine index predicts risk of parkinsonian neurodegeneration in the substantia nigra pars compacta DJ Hare, P Lei, S Ayton, BR Roberts, R Grimm, JL George, DP Bishop, ... Chemical Science 5 (6), 2160-2169, 2014 | 115 | 2014 |
| Changes in ferrous iron and glutathione promote ferroptosis and frailty in aging Caenorhabditis elegans NL Jenkins, SA James, A Salim, F Sumardy, TP Speed, M Conrad, ... Elife 9, e56580, 2020 | 114 | 2020 |
| Direct in vivo imaging of ferrous iron dyshomeostasis in ageing Caenorhabditis elegans S James, B Roberts, D Hare, M de Jonge, I Birchall, N Jenkins, R Cherny, ... Chemical Science 6, 2953-2962, 2015 | 101 | 2015 |
| Stabilization of nontoxic Aβ-oligomers: insights into the mechanism of action of hydroxyquinolines in Alzheimer's disease TM Ryan, BR Roberts, G McColl, DJ Hare, PA Doble, QX Li, M Lind, ... Journal of Neuroscience 35 (7), 2871-2884, 2015 | 89 | 2015 |
| Visualising mouse neuroanatomy and function by metal distribution using laser ablation-inductively coupled plasma-mass spectrometry imaging B Paul, DJ Hare, DP Bishop, C Paton, N Cole, MM Niedwiecki, ... Chemical Science 6 (10), 5383-5393, 2015 | 83 | 2015 |
| Caenorhabditis elegans: a model to investigate oxidative stress and metal dyshomeostasis in Parkinson's disease PM Chege, G McColl Frontiers in Aging Neuroscience 6, 2014 | 83 | 2014 |
| PBT2 reduces toxicity in a C. elegans model of polyQ aggregation and extends lifespan, reduces striatal atrophy and improves motor performance in the R6/2 mouse model of … RA Cherny, S Ayton, DI Finkelstein, AI Bush, G McColl, SM Massa Journal of Huntington's disease 1 (2), 211-219, 2012 | 77 | 2012 |
| Caenorhabditis elegans maintains highly compartmentalized cellular distribution of metals and steep concentration gradients of manganese G McColl, SA James, S Mayo, DL Howard, CG Ryan, R Kirkham, ... PloS one 7 (2), e32685, 2012 | 60 | 2012 |