A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein C Spiess, A Beil, M Ehrmann Cell 97 (3), 339-347, 1999 | 981 | 1999 |
The HtrA family of proteases: implications for protein composition and cell fate T Clausen, C Southan, M Ehrmann Molecular cell 10 (3), 443-455, 2002 | 811 | 2002 |
HTRA proteases: regulated proteolysis in protein quality control T Clausen, M Kaiser, R Huber, M Ehrmann Nature reviews Molecular cell biology 12 (3), 152-162, 2011 | 515 | 2011 |
Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine T Krojer, M Garrido-Franco, R Huber, M Ehrmann, T Clausen Nature 416 (6879), 455-459, 2002 | 499 | 2002 |
Structural basis for the regulated protease and chaperone function of DegP T Krojer, J Sawa, E Schäfer, HR Saibil, M Ehrmann, T Clausen Nature 453 (7197), 885-890, 2008 | 440 | 2008 |
Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins S Sinha, DHJ Lopes, Z Du, ES Pang, A Shanmugam, A Lomakin, ... Journal of the American Chemical Society 133 (42), 16958-16969, 2011 | 346 | 2011 |
The role of human HtrA1 in arthritic disease S Grau, PJ Richards, B Kerr, C Hughes, B Caterson, AS Williams, ... Journal of Biological Chemistry 281 (10), 6124-6129, 2006 | 346 | 2006 |
Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease C Wilken, K Kitzing, R Kurzbauer, M Ehrmann, T Clausen Cell 117 (4), 483-494, 2004 | 337 | 2004 |
VCP/p97 cooperates with YOD 1, UBXD 1 and PLAA to drive clearance of ruptured lysosomes by autophagy C Papadopoulos, P Kirchner, M Bug, D Grum, L Koerver, N Schulze, ... The EMBO journal 36 (2), 135-150, 2017 | 321 | 2017 |
Proteolysis as a regulatory mechanism M Ehrmann, T Clausen Annu. Rev. Genet. 38 (1), 709-724, 2004 | 279 | 2004 |
Implications of the serine protease HtrA1 in amyloid precursor protein processing S Grau, A Baldi, R Bussani, X Tian, R Stefanescu, M Przybylski, ... Proceedings of the National Academy of Sciences 102 (17), 6021-6026, 2005 | 241 | 2005 |
Periplasmic glycerophosphodiester phosphodiesterase of Escherichia coli, a new enzyme of the glp regulon. TJ Larson, M Ehrmann, W Boos Journal of Biological Chemistry 258 (9), 5428-5432, 1983 | 220 | 1983 |
Peptide functionalized polydiacetylene liposomes act as a fluorescent turn-on sensor for bacterial lipopolysaccharide J Wu, A Zawistowski, M Ehrmann, T Yi, C Schmuck Journal of the American Chemical Society 133 (25), 9720-9723, 2011 | 202 | 2011 |
Protein quality control in the bacterial periplasm M Merdanovic, T Clausen, M Kaiser, R Huber, M Ehrmann Annual review of microbiology 65 (1), 149-168, 2011 | 199 | 2011 |
Genetic analysis of membrane protein topology by a sandwich gene fusion approach. M Ehrmann, D Boyd, J Beckwith Proceedings of the National Academy of Sciences 87 (19), 7574-7578, 1990 | 190 | 1990 |
Serine protease HtrA1 modulates chemotherapy-induced cytotoxicity J Chien, G Aletti, A Baldi, V Catalano, P Muretto, GL Keeney, KR Kalli, ... The Journal of clinical investigation 116 (7), 1994-2004, 2006 | 187 | 2006 |
The ABC maltose transporter M Ehrmann, R Ehrle, E Hofmann, W Boos, A Schlösser Molecular microbiology 29 (3), 685-694, 1998 | 170 | 1998 |
Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins T Krojer, K Pangerl, J Kurt, J Sawa, C Stingl, K Mechtler, R Huber, ... Proceedings of the National Academy of Sciences 105 (22), 7702-7707, 2008 | 161 | 2008 |
Substrate-induced remodeling of the active site regulates human HTRA1 activity L Truebestein, A Tennstaedt, T Mönig, T Krojer, F Canellas, M Kaiser, ... Nature structural & molecular biology 18 (3), 386-388, 2011 | 159 | 2011 |
Cerebral small vessel disease-related protease HtrA1 processes latent TGF-β binding protein 1 and facilitates TGF-β signaling N Beaufort, E Scharrer, E Kremmer, V Lux, M Ehrmann, R Huber, ... Proceedings of the National Academy of Sciences 111 (46), 16496-16501, 2014 | 155 | 2014 |