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Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals M Guttman, I Amit, M Garber, C French, MF Lin, D Feldser, M Huarte, ... Nature 458 (7235), 223-227, 2009 | 4882 | 2009 |
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression AM Khalil, M Guttman, M Huarte, M Garber, A Raj, D Rivea Morales, ... Proceedings of the National Academy of Sciences 106 (28), 11667-11672, 2009 | 3364 | 2009 |
Modular regulatory principles of large non-coding RNAs M Guttman, JL Rinn Nature 482 (7385), 339-346, 2012 | 2457 | 2012 |
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response M Huarte, M Guttman, D Feldser, M Garber, MJ Koziol, ... Cell 142 (3), 409-419, 2010 | 2446 | 2010 |
lincRNAs act in the circuitry controlling pluripotency and differentiation M Guttman, J Donaghey, BW Carey, M Garber, JK Grenier, G Munson, ... Nature 477 (7364), 295-300, 2011 | 2202 | 2011 |
m6A RNA methylation promotes XIST-mediated transcriptional repression DP Patil, CK Chen, BF Pickering, A Chow, C Jackson, M Guttman, ... Nature 537 (7620), 369-373, 2016 | 1592 | 2016 |
Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs M Guttman, M Garber, JZ Levin, J Donaghey, J Robinson, X Adiconis, ... Nature biotechnology 28 (5), 503-510, 2010 | 1475 | 2010 |
Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP) EL Van Nostrand, GA Pratt, AA Shishkin, C Gelboin-Burkhart, MY Fang, ... Nature methods 13 (6), 508-514, 2016 | 1351 | 2016 |
Computational methods for transcriptome annotation and quantification using RNA-seq M Garber, MG Grabherr, M Guttman, C Trapnell Nature methods 8 (6), 469-477, 2011 | 1328 | 2011 |
A high-resolution map of human evolutionary constraint using 29 mammals K Lindblad-Toh, M Garber, O Zuk, MF Lin, BJ Parker, S Washietl, ... Nature 478 (7370), 476-482, 2011 | 1278 | 2011 |
Local regulation of gene expression by lncRNA promoters, transcription and splicing JM Engreitz, JE Haines, EM Perez, G Munson, J Chen, M Kane, ... Nature 539 (7629), 452-455, 2016 | 1275 | 2016 |
The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3 CA McHugh, CK Chen, A Chow, CF Surka, C Tran, P McDonel, ... Nature 521 (7551), 232-236, 2015 | 1153 | 2015 |
The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome JM Engreitz, A Pandya-Jones, P McDonel, A Shishkin, K Sirokman, ... Science 341 (6147), 1237973, 2013 | 1141 | 2013 |
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells S Loewer, MN Cabili, M Guttman, YH Loh, K Thomas, IH Park, M Garber, ... Nature genetics 42 (12), 1113-1117, 2010 | 1095 | 2010 |
Transcriptome-wide mapping reveals widespread dynamic-regulated pseudouridylation of ncRNA and mRNA S Schwartz, DA Bernstein, MR Mumbach, M Jovanovic, RH Herbst, ... Cell 159 (1), 148-162, 2014 | 991 | 2014 |
Long non-coding RNAs: definitions, functions, challenges and recommendations JS Mattick, PP Amaral, P Carninci, S Carpenter, HY Chang, LL Chen, ... Nature reviews Molecular cell biology 24 (6), 430-447, 2023 | 883 | 2023 |
Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins M Guttman, P Russell, NT Ingolia, JS Weissman, ES Lander Cell 154 (1), 240-251, 2013 | 833 | 2013 |
Higher-order inter-chromosomal hubs shape 3D genome organization in the nucleus SA Quinodoz, N Ollikainen, B Tabak, A Palla, JM Schmidt, E Detmar, ... Cell 174 (3), 744-757. e24, 2018 | 817 | 2018 |
The 4D nucleome project J Dekker, AS Belmont, M Guttman, VO Leshyk, JT Lis, S Lomvardas, ... Nature 549 (7671), 219-226, 2017 | 701 | 2017 |