G protein–coupled receptors targeting insulin resistance, obesity, and type 2 diabetes mellitus DM Riddy, P Delerive, RJ Summers, PM Sexton, CJ Langmead Pharmacological reviews 70 (1), 39-67, 2018 | 131 | 2018 |
New advances in targeting the resolution of inflammation: implications for specialized pro-resolving mediator GPCR drug discovery J Park, CJ Langmead, DM Riddy ACS pharmacology & translational science 3 (1), 88-106, 2020 | 103 | 2020 |
Fevipiprant (QAW039), a slowly dissociating CRTh2 antagonist with the potential for improved clinical efficacy DA Sykes, ME Bradley, DM Riddy, E Willard, J Reilly, A Miah, C Bauer, ... Molecular pharmacology 89 (5), 593-605, 2016 | 79 | 2016 |
Investigating the molecular mechanisms through which FTY720‐P causes persistent S1P1 receptor internalization DA Sykes, DM Riddy, C Stamp, ME Bradley, N McGuiness, A Sattikar, ... British journal of pharmacology 171 (21), 4797-4807, 2014 | 67 | 2014 |
Isoform-specific biased agonism of histamine H3 receptor agonists DM Riddy, AE Cook, NA Diepenhorst, S Bosnyak, R Brady, CM La Cour, ... Molecular Pharmacology 91 (2), 87-99, 2017 | 51* | 2017 |
Comparative genotypic and phenotypic analysis of human peripheral blood monocytes and surrogate monocyte-like cell lines commonly used in metabolic disease research DM Riddy, E Goy, P Delerive, RJ Summers, PM Sexton, CJ Langmead PloS one 13 (5), e0197177, 2018 | 50 | 2018 |
Acetylcholine muscarinic M4 receptors as a therapeutic target for alcohol use disorder: converging evidence from humans and rodents LC Walker, AE Berizzi, NA Chen, P Rueda, VM Perreau, K Huckstep, ... Biological Psychiatry 88 (12), 898-909, 2020 | 38 | 2020 |
A prospective study of isolated human hepatocyte function following liver resection for colorectal liver metastases: the effects of prior exposure to chemotherapy JC Hewes, D Riddy, RW Morris, AJ Woodrooffe, BR Davidson, B Fuller Journal of hepatology 45 (2), 263-270, 2006 | 35 | 2006 |
Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP2 Receptor Antagonist for Treatment of Asthma DA Sandham, L Barker, L Brown, Z Brown, D Budd, SJ Charlton, ... ACS Medicinal Chemistry Letters 8 (5), 582-586, 2017 | 34 | 2017 |
Label-free kinetics: exploiting functional hemi-equilibrium to derive rate constants for muscarinic receptor antagonists DM Riddy, C Valant, P Rueda, WN Charman, PM Sexton, RJ Summers, ... Molecular pharmacology 88 (4), 779-790, 2015 | 22 | 2015 |
Reassessment of the pharmacology of Sphingosine‐1‐phosphate S1P3 receptor ligands using the DiscoveRx PathHunter™ and Ca2+ release functional assays DM Riddy, C Stamp, DA Sykes, SJ Charlton, MR Dowling British journal of pharmacology 167 (4), 868-880, 2012 | 15 | 2012 |
Multipathway In vitro pharmacological characterization of specialized proresolving G protein-coupled receptors J Merlin, J Park, TH Vandekolk, SA Fabb, J Allinne, RJ Summers, ... Molecular Pharmacology 101 (4), 246-256, 2022 | 13 | 2022 |
Deletion of GPR21 improves glucose homeostasis and inhibits the CCL2-CCR2 axis by divergent mechanisms DM Riddy, HL Kammoun, AJ Murphy, S Bosnyak-Gladovic, ... BMJ Open Diabetes Research and Care 9 (2), e002285, 2021 | 7 | 2021 |
Mannoury la Cour C., Mocaer E., Summers RJ, Charman WN, Sexton PM, Christopoulos A., Langmead CJ, 2016. Isoform-specific biased agonism of histamine H3 receptor agonists DM Riddy, AE Cook, NA Diepenhorst, S Bosnyak, R Brady Mol Pharmacol 91 (2), 87-99, 0 | 6 | |
Mannoury la Cour C., Sors A., Charman WN, Summers RJ, Sexton PM, et al. Drug-receptor kinetics and sigma-1 receptor affinity differentiate clinically evaluated histamine H3 … DM Riddy, AE Cook, DM Shackleford, TL Pierce, E Mocaer Neuropharmacology 144, 244-255, 2019 | 4 | 2019 |
Effect of alosetron and tegaserod at the 5-HT2B receptor in human colon RA Borman, J Wade, J Root, D Riddy, K Clark, B Coleman Gastroenterology 128 (4), A271-A271, 2005 | 3 | 2005 |
Characterization of a putative orexin receptor in Ciona intestinalis sheds light on the evolution of the orexin/hypocretin system in chordates MK Rinne, L Urvas, I Mandrika, D Fridmanis, DM Riddy, CJ Langmead, ... Scientific Reports 14 (1), 7690, 2024 | 1 | 2024 |
Pharmacology of S1P3 ligands using the DiscoverRx PathHunterTM and Ca2+ release functional assays: Re-assessment of the pharmacology of VPC24191 and VPC23019. D Riddy, C Stamp, D Sykes, S Charlton, M Dowling British Journal of Pharmacology, 2012 | 1 | 2012 |
MUSCARINIC ACETYLCHOLINE RECEPTORS IN ALCOHOL USE DISORDER LC Walker, AE Berrizi, NA Chen, P Rueda, VM Perreau, K Huckstep, ... ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 44, 37-37, 2020 | | 2020 |
Bone marrow transplantation and RNAseq analysis of Gpr21−/− monocytes reveals reduced migratory function and downregulation of inflammatory genes D Riddy, H Kammoun, S Bosnyak-Gladovic, M Ziemann, R Summers, ... Australia and New Zealand Obesity Society Annual Meeting 2018, 2019 | | 2019 |