| Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavine T H Naiki, K Higuchi, M Hosokawa, T Takeda Analytical biochemistry 177 (2), 244-249, 1989 | 1500 | 1989 |
| Curcumin has potent anti‐amyloidogenic effects for Alzheimer's β‐amyloid fibrils in vitro K Ono, K Hasegawa, H Naiki, M Yamada Journal of neuroscience research 75 (6), 742-750, 2004 | 1268 | 2004 |
| Potent anti‐amyloidogenic and fibril‐destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease K Ono, Y Yoshiike, A Takashima, K Hasegawa, H Naiki, M Yamada Journal of neurochemistry 87 (1), 172-181, 2003 | 827 | 2003 |
| Direct observation of amyloid fibril growth monitored by thioflavin T fluorescence* 210 T Ban, D Hamada, K Hasegawa, H Naiki, Y Goto Journal of Biological Chemistry 278 (19), 16462-16465, 2003 | 450 | 2003 |
| ThT 101: a primer on the use of thioflavin T to investigate amyloid formation K Gade Malmos, LM Blancas-Mejia, B Weber, J Buchner, ... Amyloid 24 (1), 1-16, 2017 | 417 | 2017 |
| A toxic monomeric conformer of the polyglutamine protein Y Nagai, T Inui, HA Popiel, N Fujikake, K Hasegawa, Y Urade, Y Goto, ... Nature structural & molecular biology 14 (4), 332-340, 2007 | 411 | 2007 |
| Iron (III) induces aggregation of hyperphosphorylated τ and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of … A Yamamoto, RW Shin, K Hasegawa, H Naiki, H Sato, F Yoshimasu, ... Journal of neurochemistry 82 (5), 1137-1147, 2002 | 401 | 2002 |
| Mapping the core of the β2-microglobulin amyloid fibril by H/D exchange M Hoshino, H Katou, Y Hagihara, K Hasegawa, H Naiki, Y Goto Nature structural biology 9 (5), 332-336, 2002 | 390 | 2002 |
| Distinguishing crystal-like amyloid fibrils and glass-like amorphous aggregates from their kinetics of formation Y Yoshimura, Y Lin, H Yagi, YH Lee, H Kitayama, K Sakurai, M So, H Ogi, ... Proceedings of the National Academy of Sciences 109 (36), 14446-14451, 2012 | 357 | 2012 |
| First-order kinetic model of Alzheimer's beta-amyloid fibril extension in vitro. H Naiki, K Nakakuki Laboratory investigation; a journal of technical methods and pathology 74 (2 …, 1996 | 349 | 1996 |
| [20] Kinetic analysis of amyloid fibril formation H Naiki, F Gejyo Methods in enzymology 309, 305-318, 1999 | 335 | 1999 |
| Anti-amyloidogenic activity of tannic acid and its activity to destabilize Alzheimer's β-amyloid fibrils in vitro K Ono, K Hasegawa, H Naiki, M Yamada Biochimica et Biophysica Acta (BBA)-molecular basis of disease 1690 (3), 193-202, 2004 | 333 | 2004 |
| A seed for Alzheimer amyloid in the brain H Hayashi, N Kimura, H Yamaguchi, K Hasegawa, T Yokoseki, M Shibata, ... Journal of Neuroscience 24 (20), 4894-4902, 2004 | 292 | 2004 |
| Direct observation of Aβ amyloid fibril growth and inhibition T Ban, M Hoshino, S Takahashi, D Hamada, K Hasegawa, H Naiki, ... Journal of molecular biology 344 (3), 757-767, 2004 | 279 | 2004 |
| Establishment of a kinetic model of dialysis-related amyloid fibril extension in vitro H Naiki, N Hashimoto, S Suzuki, H Kimura, K Nakakuki, F Gejyo Amyloid 4 (4), 223-232, 1997 | 278 | 1997 |
| Interaction between Aβ (1− 42) and Aβ (1− 40) in Alzheimer's β-Amyloid fibril formation in vitro K Hasegawa, I Yamaguchi, S Omata, F Gejyo, H Naiki Biochemistry 38 (47), 15514-15521, 1999 | 267 | 1999 |
| 3D structure of amyloid protofilaments of β2-microglobulin fragment probed by solid-state NMR K Iwata, T Fujiwara, Y Matsuki, H Akutsu, S Takahashi, H Naiki, Y Goto Proceedings of the National Academy of Sciences 103 (48), 18119-18124, 2006 | 264 | 2006 |
| Kinetic analysis of amyloid fibril polymerization in vitro. H Naiki, K Higuchi, K Nakakuki, T Takeda Laboratory investigation; a journal of technical methods and pathology 65 (1 …, 1991 | 252 | 1991 |
| Presence of ras Oncogene Mutations and Human Papillomavirus DNA in Human Prostate Carcinomas K Anwar, K Nakakuki, T Shiraishi, H Naiki, R Yatani, M Inzuka Cancer research 52 (21), 5991-5996, 1992 | 235 | 1992 |
| Anti-amyloidogenic effects of antioxidants: implications for the prevention and therapeutics of Alzheimer's disease K Ono, T Hamaguchi, H Naiki, M Yamada Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1762 (6), 575-586, 2006 | 221 | 2006 |
