| Common biosynthetic origins for polycyclic tetramate macrolactams from phylogenetically diverse bacteria JAV Blodgett, DC Oh, S Cao, CR Currie, R Kolter, J Clardy Proceedings of the National Academy of Sciences 107 (26), 11692-11697, 2010 | 254 | 2010 |
| Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide JAV Blodgett, PM Thomas, G Li, JE Velasquez, WA Van Der Donk, ... Nature chemical biology 3 (8), 480-485, 2007 | 145 | 2007 |
| An unusual carbon–carbon bond cleavage reaction during phosphinothricin biosynthesis RM Cicchillo, H Zhang, JAV Blodgett, JT Whitteck, G Li, SK Nair, ... Nature 459 (7248), 871-874, 2009 | 142 | 2009 |
| Quorum-Sensing-Regulated Bactobolin Production by Burkholderia thailandensis E264 MR Seyedsayamdost, JR Chandler, JAV Blodgett, PS Lima, BA Duerkop, ... Organic letters 12 (4), 716-719, 2010 | 137 | 2010 |
| Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster RD Woodyer, Z Shao, PM Thomas, NL Kelleher, JAV Blodgett, ... Chemistry & biology 13 (11), 1171-1182, 2006 | 135 | 2006 |
| Molecular cloning, sequence analysis, and heterologous expression of the phosphinothricin tripeptide biosynthetic gene cluster from Streptomyces viridochromogenes DSM 40736 JAV Blodgett, JK Zhang, WW Metcalf Antimicrobial agents and chemotherapy 49 (1), 230-240, 2005 | 104 | 2005 |
| Cellulolytic Streptomyces strains associated with herbivorous insects share a phylogenetically linked capacity to degrade lignocellulose AJ Book, GR Lewin, BR McDonald, TE Takasuka, DT Doering, AS Adams, ... Applied and Environmental Microbiology 80 (15), 4692-4701, 2014 | 83 | 2014 |
| Targeted Discovery of Polycyclic Tetramate Macrolactams from an Environmental Streptomyces Strain S Cao, JAV Blodgett, J Clardy Organic letters 12 (20), 4652-4654, 2010 | 82 | 2010 |
| Chemical and Biological Aspects of Nutritional Immunity—Perspectives for New Anti‐Infectives that Target Iron Uptake Systems U Bilitewski, JAV Blodgett, AK Duhme‐Klair, S Dallavalle, S Laschat, ... Angewandte Chemie International Edition 56 (46), 14360-14382, 2017 | 72 | 2017 |
| Biosynthesis of 2-hydroxyethylphosphonate, an unexpected intermediate common to multiple phosphonate biosynthetic pathways Z Shao, JAV Blodgett, BT Circello, AC Eliot, R Woodyer, G Li, ... Journal of Biological Chemistry 283 (34), 23161-23168, 2008 | 56 | 2008 |
| Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface UK Shigdel, SJ Lee, ME Sowa, BR Bowman, K Robison, M Zhou, KH Pua, ... Proceedings of the National Academy of Sciences 117 (29), 17195-17203, 2020 | 49 | 2020 |
| Native and Engineered Clifednamide Biosynthesis in Multiple Streptomyces spp. Y Qi, E Ding, JAV Blodgett ACS synthetic biology 7 (2), 357-362, 2018 | 42 | 2018 |
| Conserved biosynthetic pathways for phosalacine, bialaphos and newly discovered phosphonic acid natural products JAV Blodgett, JK Zhang, X Yu, WW Metcalf The Journal of antibiotics 69 (1), 15-25, 2016 | 34 | 2016 |
| Bioinformatic and functional evaluation of actinobacterial piperazate metabolism Y Hu, Y Qi, SD Stumpf, JM D’Alessandro, JAV Blodgett ACS Chemical Biology 14 (4), 696-703, 2019 | 24 | 2019 |
| Discovery of unusual dimeric piperazyl cyclopeptides encoded by a Lentzea flaviverrucosa DSM 44664 biosynthetic supercluster C Li, Y Hu, X Wu, SD Stumpf, Y Qi, JM D’Alessandro, KK Nepal, ... Proceedings of the National Academy of Sciences 119 (17), e2117941119, 2022 | 19 | 2022 |
| A comparative metabologenomic approach reveals mechanistic insights into Streptomyces antibiotic crypticity Y Qi, KK Nepal, JAV Blodgett Proceedings of the National Academy of Sciences 118 (31), e2103515118, 2021 | 14 | 2021 |
| Compounds that participate in cooperative binding and uses thereof GL Verdine, BR Bowman, ME Sowa, JAVD Blodgett, KE Robison, ... US Patent 10,533,016, 2020 | 11 | 2020 |
| Multifunctional P450 monooxygenase CftA diversifies the clifednamide pool through tandem C–H bond activations J Yang, Y Qi, JAV Blodgett, TA Wencewicz Journal of Natural Products 85 (1), 47-55, 2022 | 9 | 2022 |
| Construction of a new integrating vector from actinophage ϕOZJ and its use in multiplex Streptomyces transformation B Ko, J D’Alessandro, L Douangkeomany, S Stumpf, A deButts, J Blodgett Journal of Industrial Microbiology and Biotechnology 47 (1), 73-81, 2020 | 9 | 2020 |
| Compositions and methods for the production of compounds BR Bowman, JAV Blodgett, GL Verdine, DC Gray, JP Morgenstern, ... US Patent 10,907,188, 2021 | 7 | 2021 |
Jon ClardyProfessor of Biological Chemistry, Harvard Medical SchoolEmail verificata su hms.harvard.edu
