Inhibition of Notch Signaling in Human Embryonic Stem Cell–Derived Neural Stem Cells Delays G1/S Phase Transition and Accelerates Neuronal Differentiation In Vitro and … L Borghese, D Dolezalova, T Opitz, S Haupt, A Leinhaas, B Steinfarz, ... Stem cells 28 (5), 955-964, 2010 | 295 | 2010 |
MicroRNAs Regulate p21Waf1/Cip1 Protein Expression and the DNA Damage Response in Human Embryonic Stem Cells D Dolezalova, M Mraz, T Barta, K Plevova, V Vinarsky, Z Holubcova, ... Stem cells 30 (7), 1362-1372, 2012 | 147 | 2012 |
MicroRNA-650 expression is influenced by immunoglobulin gene rearrangement and affects the biology of chronic lymphocytic leukemia M Mraz, D Dolezalova, K Plevova, K Stano Kozubik, V Mayerova, K Cerna, ... Blood, The Journal of the American Society of Hematology 119 (9), 2110-2113, 2012 | 121 | 2012 |
Human embryonic stem cells are capable of executing G1/S checkpoint activation T Bárta, V Vinarský, Z Holubcová, D Doležalová, J Verner, Š Pospíšilová, ... Stem Cells 28 (7), 1143-1152, 2010 | 97 | 2010 |
Human embryonic stem cells suffer from centrosomal amplification Z Holubcová, P Matula, M Sedláčková, V Vinarský, D Doležalová, T Bárta, ... Stem cells 29 (1), 46-56, 2011 | 67 | 2011 |
Differentiation of neural rosettes from human pluripotent stem cells in vitro is sequentially regulated on a molecular level and accomplished by the mechanism reminiscent of … V Fedorova, T Vanova, L Elrefae, J Pospisil, M Petrasova, V Kolajova, ... Stem cell research 40, 101563, 2019 | 66 | 2019 |
Pig models of neurodegenerative disorders: Utilization in cell replacement‐based preclinical safety and efficacy studies D Dolezalova, M Hruska‐Plochan, CR Bjarkam, JCH Sørensen, ... Journal of Comparative Neurology 522 (12), 2784-2801, 2014 | 59 | 2014 |
Human iPSC-derived neural models for studying Alzheimer’s disease: from neural stem cells to cerebral organoids M Barak, V Fedorova, V Pospisilova, J Raska, S Vochyanova, J Sedmik, ... Stem Cell Reviews and Reports 18 (2), 792-820, 2022 | 57 | 2022 |
Survival of syngeneic and allogeneic iPSC–derived neural precursors after spinal grafting in minipigs J Strnadel, C Carromeu, C Bardy, M Navarro, O Platoshyn, AN Glud, ... Science translational medicine 10 (440), eaam6651, 2018 | 56 | 2018 |
Cell cycle regulation in human embryonic stem cells: links to adaptation to cell culture T Barta, D Dolezalova, Z Holubcova, A Hampl Experimental biology and medicine 238 (3), 271-275, 2013 | 50 | 2013 |
A scalable solution for isolating human multipotent clinical-grade neural stem cells from ES precursors D Bohaciakova, M Hruska-Plochan, R Tsunemoto, WD Gifford, SP Driscoll, ... Stem cell research & therapy 10, 1-19, 2019 | 41 | 2019 |
Hypoxia/Hif1α prevents premature neuronal differentiation of neural stem cells through the activation of Hes1 J Večeřa, J Procházková, V Šumberová, V Pánská, H Paculová, ... Stem cell research 45, 101770, 2020 | 28 | 2020 |
Chromatin establishes an immature version of neuronal protocadherin selection during the naive-to-primed conversion of pluripotent stem cells A Almenar-Queralt, D Merkurjev, HS Kim, M Navarro, Q Ma, RS Chaves, ... Nature genetics 51 (12), 1691-1701, 2019 | 27 | 2019 |
Properties of human embryonic stem cells and their differentiated derivatives depend on nonhistone DNA-binding HMGB1 and HMGB2 proteins AJ Bagherpoor, D Dolezalova, T Barta, M Kučírek, SA Sani, M Ešner, ... Stem cells and development 26 (5), 328-340, 2017 | 22 | 2017 |
A robust vitronectin-derived peptide for the scalable long-term expansion and neuronal differentiation of human pluripotent stem cell (hPSC)-derived neural progenitor cells (hNPCs) D Varun, GR Srinivasan, YH Tsai, HJ Kim, J Cutts, F Petty, R Merkley, ... Acta biomaterialia 48, 120-130, 2017 | 21 | 2017 |
An efficient method for generation of Knock-out human embryonic stem cells using CRISPR/Cas9 system. D Bohaciakova, T Renzova, V Fedorova, M Barak, M Kunova Bosakova, ... Stem Cells and Development, 2017 | 16 | 2017 |
MikroRNA v onkologii O Slabý, M Svoboda, A Bešše, J Bienertová Vašků, K Černá, ... Galén, 2012 | 14 | 2012 |
Generation of six human iPSC lines from patients with a familial Alzheimer’s disease (n= 3) and sex-and age-matched healthy controls (n= 3) J Raska, H Hribkova, H Klimova, V Fedorova, M Barak, T Barta, ... Stem cell research 53, 102379, 2021 | 13 | 2021 |
Cerebral organoids derived from patients with Alzheimer’s disease with PSEN1/2 mutations have defective tissue patterning and altered development T Vanova, J Sedmik, J Raska, KA Cerna, P Taus, V Pospisilova, ... Cell Reports 42 (11), 2023 | 12 | 2023 |
A model of human neural networks reveals NPTX2 pathology in ALS and FTLD M Hruska-Plochan, VI Wiersma, KM Betz, I Mallona, S Ronchi, ... Nature 626 (8001), 1073-1083, 2024 | 11 | 2024 |