| The amyloid state and its association with protein misfolding diseases TPJ Knowles, M Vendruscolo, CM Dobson Nature reviews Molecular cell biology 15 (6), 384-396, 2014 | 2537 | 2014 |
| Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism SIA Cohen, S Linse, LM Luheshi, E Hellstrand, DA White, L Rajah, ... Proceedings of the National Academy of Sciences 110 (24), 9758-9763, 2013 | 1509 | 2013 |
| An analytical solution to the kinetics of breakable filament assembly TPJ Knowles, CA Waudby, GL Devlin, SIA Cohen, A Aguzzi, ... Science 326 (5959), 1533-1537, 2009 | 1241 | 2009 |
| The amyloid-β pathway in Alzheimer’s disease H Hampel, J Hardy, K Blennow, C Chen, G Perry, SH Kim, VL Villemagne, ... Molecular psychiatry 26 (10), 5481-5503, 2021 | 1088 | 2021 |
| Parmbsc1: a refined force field for DNA simulations I Ivani, PD Dans, A Noy, A Pérez, I Faustino, A Hospital, J Walther, ... Nature methods 13 (1), 55-58, 2016 | 960 | 2016 |
| Role of intermolecular forces in defining material properties of protein nanofibrils TP Knowles, AW Fitzpatrick, S Meehan, HR Mott, M Vendruscolo, ... science 318 (5858), 1900-1903, 2007 | 877 | 2007 |
| ALS/FTD mutation-induced phase transition of FUS liquid droplets and reversible hydrogels into irreversible hydrogels impairs RNP granule function T Murakami, S Qamar, JQ Lin, GSK Schierle, E Rees, A Miyashita, ... Neuron 88 (4), 678-690, 2015 | 856 | 2015 |
| Mapping long-range interactions in α-synuclein using spin-label NMR and ensemble molecular dynamics simulations MM Dedmon, K Lindorff-Larsen, J Christodoulou, M Vendruscolo, ... Journal of the American Chemical Society 127 (2), 476-477, 2005 | 839 | 2005 |
| FUS phase separation is modulated by a molecular chaperone and methylation of arginine cation-π interactions S Qamar, GZ Wang, SJ Randle, FS Ruggeri, JA Varela, JQ Lin, ... Cell 173 (3), 720-734. e15, 2018 | 828 | 2018 |
| Simultaneous determination of protein structure and dynamics K Lindorff-Larsen, RB Best, MA DePristo, CM Dobson, M Vendruscolo Nature 433 (7022), 128-132, 2005 | 820 | 2005 |
| Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions H Olzscha, SM Schermann, AC Woerner, S Pinkert, MH Hecht, ... Cell 144 (1), 67-78, 2011 | 793 | 2011 |
| Promoting transparency and reproducibility in enhanced molecular simulations Nature methods 16 (8), 670-673, 2019 | 772 | 2019 |
| Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation AK Buell, C Galvagnion, R Gaspar, E Sparr, M Vendruscolo, TPJ Knowles, ... Proceedings of the National Academy of Sciences 111 (21), 7671-7676, 2014 | 732 | 2014 |
| Prediction of “aggregation-prone” and “aggregation-susceptible” regions in proteins associated with neurodegenerative diseases AP Pawar, KF Dubay, J Zurdo, F Chiti, M Vendruscolo, CM Dobson Journal of molecular biology 350 (2), 379-392, 2005 | 726 | 2005 |
| Molecular mechanisms of protein aggregation from global fitting of kinetic models G Meisl, JB Kirkegaard, P Arosio, TCT Michaels, M Vendruscolo, ... Nature protocols 11 (2), 252-272, 2016 | 714 | 2016 |
| Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation C Galvagnion, AK Buell, G Meisl, TCT Michaels, M Vendruscolo, ... Nature chemical biology 11 (3), 229-234, 2015 | 694 | 2015 |
| Protein structure determination from NMR chemical shifts A Cavalli, X Salvatella, CM Dobson, M Vendruscolo Proceedings of the National Academy of Sciences 104 (23), 9615-9620, 2007 | 685 | 2007 |
| Atomic structure and hierarchical assembly of a cross-β amyloid fibril AWP Fitzpatrick, GT Debelouchina, MJ Bayro, DK Clare, MA Caporini, ... Proceedings of the National Academy of Sciences 110 (14), 5468-5473, 2013 | 674 | 2013 |
| Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers G Fusco, SW Chen, PTF Williamson, R Cascella, M Perni, JA Jarvis, ... Science 358 (6369), 1440-1443, 2017 | 652 | 2017 |
| Widespread proteome remodeling and aggregation in aging C. elegans DM Walther, P Kasturi, M Zheng, S Pinkert, G Vecchi, P Ciryam, ... Cell 161 (4), 919-932, 2015 | 618 | 2015 |
