The p65 subunit is responsible for the strong transcription activating potential of NF‐kappa B. ML Schmitz, PA Baeuerle The EMBO journal 10 (12), 3805-3817, 1991 | 1047 | 1991 |
p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor WV Berghe, S Plaisance, E Boone, K De Bosscher, ML Schmitz, W Fiers, ... Journal of Biological Chemistry 273 (6), 3285-3290, 1998 | 830 | 1998 |
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2 TG Hofmann, A Möller, H Sirma, H Zentgraf, Y Taya, W Dröge, H Will, ... Nature cell biology 4 (1), 1-10, 2002 | 746 | 2002 |
The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-κB by targeting the IκB kinase complex SP Hehner, TG Hofmann, W Dröge, ML Schmitz The Journal of Immunology 163 (10), 5617-5623, 1999 | 535 | 1999 |
Constitutive and interleukin-1-inducible phosphorylation of p65 NF-κB at serine 536 is mediated by multiple protein kinases including IκB kinase (IKK)-α, IKKβ, IKKϵ, TRAF … H Buss, A Dörrie, ML Schmitz, E Hoffmann, K Resch, M Kracht Journal of Biological Chemistry 279 (53), 55633-55643, 2004 | 498 | 2004 |
Sesquiterpene lactones specifically inhibit activation of NF-κB by preventing the degradation of IκB-α and IκB-β SP Hehner, M Heinrich, PM Bork, M Vogt, F Ratter, V Lehmann, ... Journal of Biological Chemistry 273 (3), 1288-1297, 1998 | 489 | 1998 |
Glucocorticoid-mediated repression of nuclear factor-κBdependent transcription involves direct interference with transactivation K De Bosscher, ML Schmitz, W Vanden Berghe, S Plaisance, W Fiers, ... Proceedings of the National Academy of Sciences 94 (25), 13504-13509, 1997 | 467 | 1997 |
Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF‐κB PM Bork, ML Schmitz, M Kuhnt, C Escher, M Heinrich FEBS letters 402 (1), 85-90, 1997 | 443 | 1997 |
The dual function cytokine IL-33 interacts with the transcription factor NF-κB to dampen NF-κB–stimulated gene transcription S Ali, A Mohs, M Thomas, J Klare, R Ross, ML Schmitz, MU Martin The Journal of Immunology 187 (4), 1609-1616, 2011 | 433 | 2011 |
Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-κB A Dumont, SP Hehner, TG Hofmann, M Ueffing, W DroÈge, ML Schmitz Oncogene 18 (3), 747-757, 1999 | 420 | 1999 |
NF‐κB: a multifaceted transcription factor regulated at several levels ML Schmitz, I Mattioli, H Buss, M Kracht Chembiochem 5 (10), 1348-1358, 2004 | 360 | 2004 |
The pro‐or anti‐apoptotic function of NF‐κB is determined by the nature of the apoptotic stimulus B Kaltschmidt, C Kaltschmidt, TG Hofmann, SP Hehner, W Dröge, ... European journal of biochemistry 267 (12), 3828-3835, 2000 | 359 | 2000 |
Phosphorylation of serine 468 by GSK-3β negatively regulates basal p65 NF-κB activity H Buss, A Dorrie, ML Schmitz, R Frank, M Livingstone, K Resch, M Kracht Journal of Biological Chemistry 279 (48), 49571-49574, 2004 | 341 | 2004 |
IκB-independent control of NF-κB activity by modulatory phosphorylations ML Schmitz, S Bacher, M Kracht Trends in biochemical sciences 26 (3), 186-190, 2001 | 327 | 2001 |
Activation of transcription factor NF-κB and p38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways S Wesselborg, MKA Bauer, M Vogt, ML Schmitz, K Schulze-Osthoff Journal of Biological Chemistry 272 (19), 12422-12429, 1997 | 298 | 1997 |
Transient and selective NF-κB p65 serine 536 phosphorylation induced by T cell costimulation is mediated by IκB kinase β and controls the kinetics of p65 nuclear import I Mattioli, A Sebald, C Bucher, RP Charles, H Nakano, M Kracht, ... The Journal of Immunology 172 (10), 6336-6344, 2004 | 294 | 2004 |
Sex reversal by loss of the C–terminal transactivation domain of human SOX9 P Südbeck, ML Schmitz, PA Baeuerle, G Scherer Nature genetics 13 (2), 230-232, 1996 | 267 | 1996 |
SUMO5, a novel poly-SUMO isoform, regulates PML nuclear bodies YC Liang, CC Lee, YL Yao, CC Lai, ML Schmitz, WM Yang Scientific reports 6 (1), 26509, 2016 | 244 | 2016 |
Mutational Analysis of the SOX9 Gene in Campomelic Dysplasia and Autosomal Sex Reversal: Lack of Genotype/Phenotype Correlations J Meyer, P Südbeck, M Held, T Wagner, ML Schmitz, F Dagna Bricarelli, ... Human molecular genetics 6 (1), 91-98, 1997 | 220 | 1997 |
Interaction of the COOH-terminal transactivation domain of p65 NF-κB with TATA-binding protein, transcription factor IIB, and coactivators ML Schmitz, G Stelzer, H Altmann, M Meisterernst, PA Baeuerle Journal of Biological Chemistry 270 (13), 7219-7226, 1995 | 210 | 1995 |