| Three‐dimensional models of cancer for pharmacology and cancer cell biology: capturing tumor complexity in vitro/ex vivo JA Hickman, R Graeser, R de Hoogt, S Vidic, C Brito, M Gutekunst, ... Biotechnology journal 9 (9), 1115-1128, 2014 | 451 | 2014 |
| Process engineering of human pluripotent stem cells for clinical application M Serra, C Brito, C Correia, PM Alves Trends in biotechnology 30 (6), 350-359, 2012 | 346 | 2012 |
| Polyphenols journey through blood-brain barrier towards neuronal protection I Figueira, G Garcia, RC Pimpão, AP Terrasso, I Costa, AF Almeida, ... Scientific reports 7 (1), 11456, 2017 | 276 | 2017 |
| Mind the gap—deficits in our knowledge of aspects impacting the bioavailability of phytochemicals and their metabolites—a position paper focusing on carotenoids and polyphenols T Bohn, GJ McDougall, A Alegría, M Alminger, E Arrigoni, AM Aura, ... Molecular Nutrition & Food Research 59 (7), 1307-1323, 2015 | 274 | 2015 |
| Human liver cell spheroids in extended perfusion bioreactor culture for repeated‐dose drug testing RM Tostões, SB Leite, M Serra, J Jensen, P Björquist, MJT Carrondo, ... Hepatology 55 (4), 1227-1236, 2012 | 272 | 2012 |
| Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery K Stock, MF Estrada, S Vidic, K Gjerde, A Rudisch, VE Santo, M Barbier, ... Scientific reports 6 (1), 28951, 2016 | 257 | 2016 |
| 3D-3-culture: A tool to unveil macrophage plasticity in the tumour microenvironment SP Rebelo, C Pinto, TR Martins, N Harrer, MF Estrada, P Loza-Alvarez, ... Biomaterials 163, 185-197, 2018 | 224 | 2018 |
| Microencapsulation technology: a powerful tool for integrating expansion and cryopreservation of human embryonic stem cells M Serra, C Correia, R Malpique, C Brito, J Jensen, P Bjorquist, ... PloS one 6 (8), e23212, 2011 | 206 | 2011 |
| Improving expansion of pluripotent human embryonic stem cells in perfused bioreactors through oxygen control M Serra, C Brito, MFQ Sousa, J Jensen, R Tostões, J Clemente, R Strehl, ... Journal of biotechnology 148 (4), 208-215, 2010 | 183 | 2010 |
| A multi-organ chip co-culture of neurospheres and liver equivalents for long-term substance testing EM Materne, AP Ramme, AP Terrasso, M Serra, PM Alves, C Brito, ... Journal of biotechnology 205, 36-46, 2015 | 176 | 2015 |
| Modelling the tumour microenvironment in long-term microencapsulated 3D co-cultures recapitulates phenotypic features of disease progression MF Estrada, SP Rebelo, EJ Davies, MT Pinto, H Pereira, VE Santo, ... Biomaterials 78, 50-61, 2016 | 140 | 2016 |
| Adaptable stirred-tank culture strategies for large scale production of multicellular spheroid-based tumor cell models VE Santo, MF Estrada, SP Rebelo, S Abreu, I Silva, C Pinto, SC Veloso, ... Journal of biotechnology 221, 118-129, 2016 | 122 | 2016 |
| Drug screening in 3D in vitro tumor models: overcoming current pitfalls of efficacy read‐outs VE Santo, SP Rebelo, MF Estrada, PM Alves, E Boghaert, C Brito Biotechnology journal 12 (1), 1600505, 2017 | 109 | 2017 |
| Combining hypoxia and bioreactor hydrodynamics boosts induced pluripotent stem cell differentiation towards cardiomyocytes C Correia, M Serra, N Espinha, M Sousa, C Brito, K Burkert, Y Zheng, ... Stem cell reviews and reports 10, 786-801, 2014 | 93 | 2014 |
| Three‐dimensional co‐culture of human hepatocytes and mesenchymal stem cells: improved functionality in long‐term bioreactor cultures SP Rebelo, R Costa, MM Silva, P Marcelino, C Brito, PM Alves Journal of tissue engineering and regenerative medicine 11 (7), 2034-2045, 2017 | 91 | 2017 |
| SPIM-fluid: open source light-sheet based platform for high-throughput imaging EJ Gualda, H Pereira, T Vale, MF Estrada, C Brito, N Moreno Biomedical optics express 6 (11), 4447-4456, 2015 | 81 | 2015 |
| Cysteine allows ovarian cancer cells to adapt to hypoxia and to escape from carboplatin cytotoxicity SC Nunes, C Ramos, F Lopes-Coelho, CO Sequeira, F Silva, ... Scientific reports 8 (1), 9513, 2018 | 78 | 2018 |
| Recapitulation of human neural microenvironment signatures in iPSC-derived NPC 3D differentiation D Simão, MM Silva, AP Terrasso, F Arez, MFQ Sousa, NZ Mehrjardi, ... Stem Cell Reports 11 (2), 552-564, 2018 | 76 | 2018 |
| Different expression levels of α3/4 fucosyltransferases and Lewis determinants in ovarian carcinoma tissues and cell lines C Escrevente, E Machado, C Brito, CA Reis, A Stoeck, S Runz, A Marme, ... International journal of oncology 29 (3), 557-566, 2006 | 76 | 2006 |
| HepaRG microencapsulated spheroids in DMSO-free culture: novel culturing approaches for enhanced xenobiotic and biosynthetic metabolism SP Rebelo, R Costa, M Estrada, V Shevchenko, C Brito, PM Alves Archives of toxicology 89, 1347-1358, 2015 | 73 | 2015 |
Paula M AlvesiBET, CEOEmail verificata su itqb.unl.pt
