Prion-like spreading of pathological α-synuclein in brain M Masuda-Suzukake, T Nonaka, M Hosokawa, T Oikawa, T Arai, ... Brain 136 (4), 1128-1138, 2013 | 972 | 2013 |
Pathological alpha-synuclein propagates through neural networks M Masuda-Suzukake, T Nonaka, M Hosokawa, M Kubo, A Shimozawa, ... Acta neuropathologica communications 2, 1-12, 2014 | 272 | 2014 |
The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis K Imamura, Y Izumi, A Watanabe, K Tsukita, K Woltjen, T Yamamoto, ... Science Translational Medicine 9 (391), eaaf3962, 2017 | 261 | 2017 |
Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes Y Tanaka, G Suzuki, T Matsuwaki, M Hosokawa, G Serrano, TG Beach, ... Human molecular genetics 26 (5), 969-988, 2017 | 183 | 2017 |
Phosphorylated and cleaved TDP‐43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP‐43 proteinopathy T Arai, M Hasegawa, T Nonoka, F Kametani, M Yamashita, M Hosokawa, ... Neuropathology 30 (2), 170-181, 2010 | 168 | 2010 |
Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease C Schwab, M Hosokawa, PL McGeer Experimental neurology 188 (1), 52-64, 2004 | 165 | 2004 |
Molecular analysis and biochemical classification of TDP-43 proteinopathy H Tsuji, T Arai, F Kametani, T Nonaka, M Yamashita, M Suzukake, ... Brain 135 (11), 3380-3391, 2012 | 125 | 2012 |
Expression of complement messenger RNAs and proteins by human oligodendroglial cells M Hosokawa, A Klegeris, J Maguire, PL McGeer Glia 42 (4), 417-423, 2003 | 112 | 2003 |
Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice M Hosokawa, T Arai, M Masuda-Suzukake, T Nonaka, M Yamashita, ... PloS one 7 (12), e52389, 2012 | 111 | 2012 |
A chemical chaperone, sodium 4-phenylbutyric acid, attenuates the pathogenic potency in human α-synuclein A30P+ A53T transgenic mice K Ono, M Ikemoto, T Kawarabayashi, M Ikeda, T Nishinakagawa, ... Parkinsonism & related disorders 15 (9), 649-654, 2009 | 96 | 2009 |
Enhanced tumor metastases in rats following cryosurgery of primary tumor. T Yamashita, K Hayakawa, M Hosokawa, T Kodama, N Inoue, K Tomita, ... Gann= Gan 73 (2), 222-228, 1982 | 82 | 1982 |
Natural killer cells of Parkinson's disease patients are set up for activation: a possible role for innate immunity in the pathogenesis of this disease T Mihara, M Nakashima, A Kuroiwa, Y Akitake, K Ono, M Hosokawa, ... Parkinsonism & related disorders 14 (1), 46-51, 2008 | 81 | 2008 |
Moderate maternal food restriction in mice impairs physical growth, behaviors, and neurodevelopment of offspring HH Akitake Y, Katsuragi S, Hosokawa M, Mishima K, Ikeda T, Miyazato M Neutrition Research 35 (1), 76-87, 2015 | 70* | 2015 |
Localization of fused in sarcoma (FUS) protein to the post-synaptic density in the brain N Aoki, S Higashi, I Kawakami, Z Kobayashi, M Hosokawa, O Katsuse, ... Acta neuropathologica 124, 383-394, 2012 | 64 | 2012 |
α-synuclein strains that cause distinct pathologies differentially inhibit proteasome G Suzuki, S Imura, M Hosokawa, R Katsumata, T Nonaka, SI Hisanaga, ... Elife 9, e56825, 2020 | 61 | 2020 |
Molecular cloning of guinea pig membrane cofactor protein: preferential expression in testis. M Hosokawa, M Nonaka, N Okada, M Nonaka, H Okada Journal of immunology (Baltimore, Md.: 1950) 157 (11), 4946-4952, 1996 | 60 | 1996 |
Microsomal prostaglandin E synthase‐1 is induced in alzheimer's disease and its deletion mitigates alzheimer's disease‐like pathology in a mouse model Y Akitake, Y Nakatani, D Kamei, M Hosokawa, H Akatsu, S Uematsu, ... Journal of neuroscience research 91 (7), 909-919, 2013 | 57 | 2013 |
C9ORF72 dipeptide repeat poly-GA inclusions promote intracellular aggregation of phosphorylated TDP-43 T Nonaka, M Masuda-Suzukake, M Hosokawa, A Shimozawa, S Hirai, ... Human molecular genetics 27 (15), 2658-2670, 2018 | 56 | 2018 |
Progranulin reduction is associated with increased tau phosphorylation in P301L tau transgenic mice M Hosokawa, T Arai, M Masuda-Suzukake, H Kondo, T Matsuwaki, ... Journal of Neuropathology & Experimental Neurology 74 (2), 158-165, 2015 | 49 | 2015 |
Distinct pathways leading to TDP-43-induced cellular dysfunctions M Yamashita, T Nonaka, S Hirai, A Miwa, H Okado, T Arai, M Hosokawa, ... Human molecular genetics 23 (16), 4345-4356, 2014 | 49 | 2014 |