Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin B Wienert, APW Funnell, LJ Norton, RCM Pearson, LE Wilkinson-White, ... Nature communications 6 (1), 7085, 2015 | 133 | 2015 |
A Cas9 variant for efficient generation of indel-free knockin or gene-corrected human pluripotent stem cells SE Howden, B McColl, A Glaser, J Vadolas, S Petrou, MH Little, ... Stem cell reports 7 (3), 508-517, 2016 | 121 | 2016 |
Alveolar macrophages regulate the induction of primary cytotoxic T-lymphocyte responses during influenza virus infection OL Wijburg, S DiNatale, JIM Vadolas, N Van Rooijen, RA Strugnell Journal of virology 71 (12), 9450-9457, 1997 | 97 | 1997 |
GFP to BFP conversion: a versatile assay for the quantification of CRISPR/Cas9-mediated genome editing A Glaser, B McColl, J Vadolas Molecular Therapy-Nucleic Acids 5, 2016 | 91 | 2016 |
Intranasal immunization with liposomes induces strong mucosal immune responses in mice J Vadolas, JK Davies, PJ Wright, RA Strugnell European Journal of Immunology 25 (4), 969-975, 1995 | 84 | 1995 |
Controlling α-globin: a review of α-globin expression and its impact on β-thalassemia HPJ Voon, J Vadolas Haematologica 93 (12), 1868-1876, 2008 | 81 | 2008 |
Engineering EGFP reporter constructs into a 200 kb human β-globin BAC clone using GET Recombination M Orford, M Nefedov, J Vadolas, F Zaibak, R Williamson, PA Ioannou Nucleic acids research 28 (18), e84-e84, 2000 | 79 | 2000 |
DNA vaccines for bacterial infections RA Strugnell, D Drew, J Mercieca, S DiNatale, N Firez, SJ Dunstan, ... Immunology and cell biology 75 (4), 364-369, 1997 | 78 | 1997 |
Neutralization epitopes of human rhinovirus type 2 G Appleyard, SM Russell, BE Clarke, SA Speller, M Trowbridge, ... Journal of General Virology 71 (6), 1275-1282, 1990 | 70 | 1990 |
The role of macrophages in the induction and regulation of immunity elicited by exogenous antigens OLC Wijburg, GPJM van den Dobbelsteen, J Vadolas, A Sanders, ... European journal of immunology 28 (2), 479-487, 1998 | 67 | 1998 |
Nucleic acid vaccination of sheep: Use in combination with a conventional adjuvanted vaccine against Taenia ovis JS Rothel, JG Waterkeyn, RA Strugnell, PR Wood, HF Seow, J Vadolas, ... Immunology and Cell Biology 75 (1), 41-46, 1997 | 63 | 1997 |
A humanized mouse model for a common β0-thalassemia mutation D Jamsai, F Zaibak, W Khongnium, J Vadolas, L Voullaire, KJ Fowler, ... Genomics 85 (4), 453-461, 2005 | 60 | 2005 |
Intranasal immunization with yeast‐expressed 19 kD carboxyl‐terminal fragment of Plasmodium yoelii merozoite surface protein‐1 (yMSP119) induces protective … C Hirunpetcharat, D Stanisic, XQ Liu, J Vadolas, RA Strugnell, R Lee, ... Parasite immunology 20 (9), 413-420, 1998 | 57 | 1998 |
The potential of bone marrow stem cells to correct liver dysfunction in a mouse model of Wilson's disease KJ Allen, DMY Cheah, XL Lee, NE Pettigrew-Buck, J Vadolas, JFB Mercer, ... Cell transplantation 13 (7-8), 765-774, 2004 | 56 | 2004 |
Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β‐like globin genes M Roosjen, B McColl, B Kao, LJ Gearing, ME Blewitt, J Vadolas The FASEB Journal 28 (4), 1610-1620, 2014 | 54 | 2014 |
Imbalanced globin chain synthesis determines erythroid cell pathology in thalassemic mice K Srinoun, S Svasti, W Chumworathayee, J Vadolas, P Vattanaviboon, ... Haematologica 94 (9), 1211, 2009 | 53 | 2009 |
A humanized BAC transgenic/knockout mouse model for HbE/β-thalassemia D Jamsai, F Zaibak, J Vadolas, L Voullaire, KJ Fowler, S Gazeas, ... Genomics 88 (3), 309-315, 2006 | 53 | 2006 |
Labdane Diterpenes from the Aerial Parts of Curcuma comosa Enhance Fetal Hemoglobin Production in an Erythroid Cell Line R Chokchaisiri, N Chaneiam, S Svasti, S Fucharoen, J Vadolas, ... Journal of natural products 73 (4), 724-728, 2010 | 46 | 2010 |
Animal models of β-hemoglobinopathies: utility and limitations B McColl, J Vadolas Journal of Blood Medicine, 263-274, 2016 | 39 | 2016 |
Humanized β-thalassemia mouse model containing the common IVSI-110 splicing mutation J Vadolas, M Nefedov, H Wardan, S Mansooriderakshan, L Voullaire, ... Journal of Biological Chemistry 281 (11), 7399-7405, 2006 | 39 | 2006 |