AMPK: a nutrient and energy sensor that maintains energy homeostasis DG Hardie, FA Ross, SA Hawley Nature reviews Molecular cell biology 13 (4), 251-262, 2012 | 4630 | 2012 |
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism BB Kahn, T Alquier, D Carling, DG Hardie Cell metabolism 1 (1), 15-25, 2005 | 3499 | 2005 |
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy DG Hardie Nature reviews Molecular cell biology 8 (10), 774-785, 2007 | 2697 | 2007 |
The mechanisms of action of metformin G Rena, DG Hardie, ER Pearson Diabetologia 60 (9), 1577-1585, 2017 | 2295 | 2017 |
Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade SA Hawley, J Boudeau, JL Reid, KJ Mustard, L Udd, TP Mäkelä, ... Journal of biology 2, 1-16, 2003 | 2109 | 2003 |
Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase SA Hawley, DA Pan, KJ Mustard, L Ross, J Bain, AM Edelman, ... Cell metabolism 2 (1), 9-19, 2005 | 1996 | 2005 |
The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell? DG Hardie, D Carling, M Carlson Annual review of biochemistry 67 (1), 821-855, 1998 | 1862 | 1998 |
AMP-activated protein kinase—an energy sensor that regulates all aspects of cell function DG Hardie Genes & development 25 (18), 1895-1908, 2011 | 1814 | 2011 |
The AMP‐activated protein kinase: fuel gauge of the mammalian cell? DG Hardie, D Carling European journal of biochemistry 246 (2), 259-273, 1997 | 1736 | 1997 |
AMP-activated protein kinase in metabolic control and insulin signaling MC Towler, DG Hardie Circulation research 100 (3), 328-341, 2007 | 1663 | 2007 |
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1 JM Lizcano, O Göransson, R Toth, M Deak, NA Morrice, J Boudeau, ... The EMBO journal 23 (4), 833-843, 2004 | 1607 | 2004 |
Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated … SA Hawley, M Davison, A Woods, SP Davies, RK Beri, D Carling, ... Journal of Biological Chemistry 271 (44), 27879-27887, 1996 | 1531 | 1996 |
5‐Aminoimidazole‐4‐carboxamide ribonucleoside: a specific method for activating AMP‐activated protein kinase in intact cells? JM Corton, JG Gillespie, SA Hawley, DG Hardie European journal of biochemistry 229 (2), 558-565, 1995 | 1508 | 1995 |
The AMP-activated protein kinase pathway–new players upstream and downstream DG Hardie Journal of cell science 117 (23), 5479-5487, 2004 | 1493 | 2004 |
AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes WW Winder, DG Hardie American Journal of Physiology-Endocrinology and Metabolism 277 (1), E1-E10, 1999 | 1460 | 1999 |
AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle GF Merrill, EJ Kurth, DG Hardie, WW Winder American Journal of Physiology-Endocrinology and Metabolism 273 (6), E1107-E1112, 1997 | 1339 | 1997 |
Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status DG Hardie Endocrinology 144 (12), 5179-5183, 2003 | 1306 | 2003 |
Metabolism of inflammation limited by AMPK and pseudo-starvation LAJ O'Neill, DG Hardie Nature 493 (7432), 346-355, 2013 | 1238 | 2013 |
Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise WW Winder, DG Hardie American Journal of Physiology-Endocrinology and Metabolism 270 (2), E299-E304, 1996 | 1114 | 1996 |
Management of cellular energy by the AMP-activated protein kinase system DG Hardie, JW Scott, DA Pan, ER Hudson FEBS letters 546 (1), 113-120, 2003 | 1089 | 2003 |