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DAVID R LIGHT
DAVID R LIGHT
Illexcor, Sanofi, Bioverativ, Biogen, Bayer, Berlex, Genentech
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Anno
Structural basis for the anticoagulant activity of the thrombin–thrombomodulin complex
P Fuentes-Prior, Y Iwanaga, R Huber, R Pagila, G Rumennik, M Seto, ...
Nature 404 (6777), 518-525, 2000
4202000
Rubber elongation factor from Hevea brasiliensis: identification, characterization, and role in rubber biosynthesis.
MS Dennis, DR Light
Journal of Biological Chemistry 264 (31), 18608-18617, 1989
3431989
Characteristics of the cofactor requirements for the superoxide-generating NADPH oxidase of human polymorphonuclear leukocytes
DR Light, C Walsh, AM O'Callaghan, EJ Goetzl, AI Tauber
Biochemistry 20 (6), 1468-1476, 1981
2961981
Oxidation of a specific methionine in thrombomodulin by activated neutrophil products blocks cofactor activity. A potential rapid mechanism for modulation of coagulation.
CB Glaser, J Morser, JH Clarke, E Blasko, K McLean, I Kuhn, RJ Chang, ...
The Journal of clinical investigation 90 (6), 2565-2573, 1992
2941992
Production of 2-Keto-L-Gulonate, an Intermediate in L-Ascorbate Synthesis, by a Genetically Modified Erwinia herbicola
S Anderson, CB Marks, R Lazarus, J Miller, K Stafford, J Seymour, D Light, ...
Science 230 (4722), 144-149, 1985
2731985
The human growth hormone receptor. Secretion from Escherichia coli and disulfide bonding pattern of the extracellular binding domain.
G Fuh, MG Mulkerrin, S Bass, N McFarland, M Brochier, JH Bourell, ...
Journal of Biological Chemistry 265 (6), 3111-3115, 1990
2511990
Studies on the chirality of sulfoxidation catalyzed by bacterial flavoenzyme cyclohexanone monooxygenase and hog liver FAD-containing monooxygenase
DR Light, DJ Waxman, C Walsh
Biochemistry 21 (10), 2490-2498, 1982
2001982
An inhibitor of activated thrombin-activatable fibrinolysis inhibitor potentiates tissue-type plasminogen activator-induced thrombolysis in a rabbit jugular vein thrombolysis model
M Nagashima, M Werner, M Wang, L Zhao, DR Light, R Pagila, J Morser, ...
Thrombosis research 98 (4), 333-342, 2000
1912000
Fasudil, a Rho-kinase inhibitor, attenuates angiotensin II–induced abdominal aortic aneurysm in apolipoprotein E–deficient mice by inhibiting apoptosis and proteolysis
YX Wang, B Martin-McNulty, V da Cunha, J Vincelette, X Lu, Q Feng, ...
Circulation 111 (17), 2219-2226, 2005
1632005
Preparation, Characterization, and the Crystal Structure of the Inhibitor ZK-807834 (CI-1031) Complexed with Factor Xa,
M Adler, DD Davey, GB Phillips, SH Kim, J Jancarik, G Rumennik, ...
Biochemistry 39 (41), 12534-12542, 2000
1382000
Amino acid sequence of rubber elongation factor protein associated with rubber particles in Hevea latex
MS Dennis, WJ Henzel, J Bell, W Kohr, DR Light
Journal of Biological Chemistry 264 (31), 18618-18626, 1989
1381989
Purification of a prenyltransferase that elongates cis-polyisoprene rubber from the latex of Hevea brasiliensis
DR Light, MS Dennis
Journal of Biological Chemistry 264 (31), 18589-18597, 1989
1361989
Chiral sulfoxidations catalyzed by rat liver cytochromes P-450
DJ Waxman, DR Light, C Walsh
Biochemistry 21 (10), 2499-2507, 1982
1291982
Analytical and preparative high-performance liquid chromatography separation of flavin and flavin analog coenzymes
DR Light, C Walsh, MA Marletta
Analytical biochemistry 109 (1), 87-93, 1980
1181980
Crystal Structures of Two Potent Nonamidine Inhibitors Bound to Factor Xa,
M Adler, MJ Kochanny, B Ye, G Rumennik, DR Light, S Biancalana, ...
Biochemistry 41 (52), 15514-15523, 2002
1152002
Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture
JA Xuan, D Schneider, P Toy, R Lin, A Newton, Y Zhu, S Finster, D Vogel, ...
Cancer research 66 (7), 3611-3619, 2006
992006
In Vivo Biodistribution, PET Imaging, and Tumor Accumulation of 86Y-and 111In-Antimindin/RG-1, Engineered Antibody Fragments in LNCaP Tumor–Bearing Nude Mice
DW Schneider, T Heitner, B Alicke, DR Light, K McLean, N Satozawa, ...
Journal of Nuclear Medicine 50 (3), 435-443, 2009
982009
Modulation of glycosaminoglycan addition in naturally expressed and recombinant human thrombomodulin.
JH Lin, K McLean, J Morser, TA Young, RM Wydro, WH Andrews, ...
Journal of Biological Chemistry 269 (40), 25021-25030, 1994
981994
Inhibition of Rho-kinase by fasudil attenuated angiotensin II-induced cardiac hypertrophy in apolipoprotein E deficient mice
YX Wang, V da Cunha, B Martin-McNulty, J Vincelette, W Li, DF Choy, ...
European journal of pharmacology 512 (2-3), 215-222, 2005
922005
Steroid binding properties of beef adrenal cortical cytochrome P-450 which catalyzes the conversion of cholesterol into pregnenolone.
NR Orme-Johnson, DR Light, RW White-Stevens, WH Orme-Johnson
Journal of Biological Chemistry 254 (6), 2103-2111, 1979
911979
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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