| Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus HX Liao, R Lynch, T Zhou, F Gao, SM Alam, SD Boyd, AZ Fire, KM Roskin, ... Nature 496 (7446), 469-476, 2013 | 1140 | 2013 |
| Stochasticity in transcriptional regulation: origins, consequences, and mathematical representations TB Kepler, TC Elston Biophysical journal 81 (6), 3116-3136, 2001 | 1116 | 2001 |
| Invertebrate immune systems–not homogeneous, not simple, not well understood ES Loker, CM Adema, SM Zhang, TB Kepler Immunological reviews 198 (1), 10-24, 2004 | 773 | 2004 |
| Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers. S Han, K Hathcock, B Zheng, TB Kepler, R Hodes, G Kelsoe Journal of immunology (Baltimore, Md.: 1950) 155 (2), 556-567, 1995 | 638 | 1995 |
| B-cell–lineage immunogen design in vaccine development with HIV-1 as a case study BF Haynes, G Kelsoe, SC Harrison, TB Kepler Nature biotechnology 30 (5), 423-433, 2012 | 584 | 2012 |
| Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors M Bonsignori, KK Hwang, X Chen, CY Tsao, L Morris, E Gray, DJ Marshall, ... Journal of virology 85 (19), 9998-10009, 2011 | 511 | 2011 |
| Classification of osteoarthritis biomarkers: a proposed approach DC Bauer, DJ Hunter, SB Abramson, M Attur, M Corr, D Felson, ... Osteoarthritis and Cartilage 14 (8), 723-727, 2006 | 510 | 2006 |
| Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin JRR Whittle, R Zhang, S Khurana, LR King, J Manischewitz, H Golding, ... Proceedings of the National Academy of Sciences 108 (34), 14216-14221, 2011 | 492 | 2011 |
| Pathway level analysis of gene expression using singular value decomposition J Tomfohr, J Lu, TB Kepler BMC bioinformatics 6, 1-11, 2005 | 459 | 2005 |
| Advantage of rare HLA supertype in HIV disease progression E Trachtenberg, B Korber, C Sollars, TB Kepler, PT Hraber, E Hayes, ... Nature medicine 9 (7), 928-935, 2003 | 459 | 2003 |
| Diversification of Ig superfamily genes in an invertebrate SM Zhang, CM Adema, TB Kepler, ES Loker Science 305 (5681), 251-254, 2004 | 446 | 2004 |
| Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2 HX Liao, M Bonsignori, SM Alam, JS McLellan, GD Tomaras, MA Moody, ... Immunity 38 (1), 176-186, 2013 | 445 | 2013 |
| A model of large-scale proteome evolution RV Solé, R Pastor-Satorras, E Smith, TB Kepler Advances in Complex Systems 5 (01), 43-54, 2002 | 425 | 2002 |
| Cyclic re-entry of germinal center B cells and the efficiency of affinity maturation TB Kepler, AS Perelson Immunology today 14 (8), 412-415, 1993 | 363 | 1993 |
| The T helper type 2 response to cysteine proteases requires dendritic cell–basophil cooperation via ROS-mediated signaling H Tang, W Cao, SP Kasturi, R Ravindran, HI Nakaya, K Kundu, N Murthy, ... Nature immunology 11 (7), 608-617, 2010 | 351 | 2010 |
| Maturation pathway from germline to broad HIV-1 neutralizer of a CD4-mimic antibody M Bonsignori, T Zhou, Z Sheng, L Chen, F Gao, MG Joyce, G Ozorowski, ... Cell 165 (2), 449-463, 2016 | 330 | 2016 |
| Microbial colonization influences early B-lineage development in the gut lamina propria DR Wesemann, AJ Portuguese, RM Meyers, MP Gallagher, K Cluff-Jones, ... Nature 501 (7465), 112-115, 2013 | 324 | 2013 |
| Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies F Gao, M Bonsignori, HX Liao, A Kumar, SM Xia, X Lu, F Cai, KK Hwang, ... Cell 158 (3), 481-491, 2014 | 322 | 2014 |
| Drug concentration heterogeneity facilitates the evolution of drug resistance TB Kepler, AS Perelson Proceedings of the National Academy of Sciences 95 (20), 11514-11519, 1998 | 317 | 1998 |
| Complex antigens drive permissive clonal selection in germinal centers M Kuraoka, AG Schmidt, T Nojima, F Feng, A Watanabe, D Kitamura, ... Immunity 44 (3), 542-552, 2016 | 302 | 2016 |
