| Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR‐mediated gene disruption and other … C Baker Brachmann, A Davies, GJ Cost, E Caputo, J Li, P Hieter, ... Yeast 14 (2), 115-132, 1998 | 4141 | 1998 |
| A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family JS Smith, CB Brachmann, I Celic, MA Kenna, S Muhammad, VJ Starai, ... Proceedings of the National Academy of Sciences 97 (12), 6658-6663, 2000 | 964 | 2000 |
| Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum. S Shak, DJ Capon, R Hellmiss, SA Marsters, CL Baker Proceedings of the National Academy of Sciences 87 (23), 9188-9192, 1990 | 912 | 1990 |
| The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability. CB Brachmann, JM Sherman, SE Devine, EE Cameron, L Pillus, ... Genes & development 9 (23), 2888-2902, 1995 | 842 | 1995 |
| Distribution of a limited Sir2 protein pool regulates the strength of yeast rDNA silencing and is modulated by Sir4p JS Smith, CB Brachmann, L Pillus, JD Boeke Genetics 149 (3), 1205-1219, 1998 | 209 | 1998 |
| SPARC Expression Did Not Predict Efficacy of nab-Paclitaxel plus Gemcitabine or Gemcitabine Alone for Metastatic Pancreatic Cancer in an Exploratory Analysis … M Hidalgo, C Plaza, M Musteanu, P Illei, CB Brachmann, C Heise, ... Clinical Cancer Research 21 (21), 4811-4818, 2015 | 145 | 2015 |
| The Drosophila bcl-2 family member dBorg-1 functions in the apoptotic response to UV-irradiation CB Brachmann, OW Jassim, BD Wachsmuth, RL Cagan Current biology 10 (9), 547-550, 2000 | 137 | 2000 |
| The Conserved Core of a Human SIR2 Homologue Functions in Yeast Silencing JM Sherman, EM Stone, LL Freeman-Cook, CB Brachmann, JD Boeke, ... Molecular biology of the cell 10 (9), 3045-3059, 1999 | 135 | 1999 |
| The Molecular Mechanisms of OPA1-Mediated Optic Atrophy in Drosophila Model and Prospects for Antioxidant Treatment W Yarosh, J Monserrate, JJ Tong, S Tse, PK Le, K Nguyen, ... PLoS genetics 4 (1), e6, 2008 | 128 | 2008 |
| Patterning the fly eye: the role of apoptosis CB Brachmann, RL Cagan TRENDS in Genetics 19 (2), 91-96, 2003 | 124 | 2003 |
| ACVR1/JAK1/JAK2 inhibitor momelotinib reverses transfusion dependency and suppresses hepcidin in myelofibrosis phase 2 trial ST Oh, M Talpaz, AT Gerds, V Gupta, S Verstovsek, R Mesa, CB Miller, ... Blood advances 4 (18), 4282-4291, 2020 | 122 | 2020 |
| Invading the yeast nucleus: a nuclear localization signal at the C terminus of Ty1 integrase is required for transposition in vivo MA Kenna, CB Brachmann, SE Devine, JD Boeke Molecular and cellular biology, 1998 | 117 | 1998 |
| Albumin-bound nanoparticle (nab) paclitaxel exhibits enhanced paclitaxel tissue distribution and tumor penetration N Chen, C Brachmann, X Liu, DW Pierce, J Dey, WS Kerwin, Y Li, S Zhou, ... Cancer chemotherapy and pharmacology 76, 699-712, 2015 | 113 | 2015 |
| A phase 1/2, open-label study evaluating twice-daily administration of momelotinib in myelofibrosis V Gupta, RA Mesa, MWN Deininger, CE Rivera, S Sirhan, CB Brachmann, ... Haematologica 102 (1), 94, 2017 | 100 | 2017 |
| A randomized, controlled phase III trial of nab-Paclitaxel versus dacarbazine in chemotherapy-naïve patients with metastatic melanoma EM Hersh, M Del Vecchio, MP Brown, R Kefford, C Loquai, A Testori, ... Annals of Oncology 26 (11), 2267-2274, 2015 | 92 | 2015 |
| The Schizosaccharomyces pombe hst4 + Gene Is a SIR2 Homologue with Silencing and Centromeric Functions LL Freeman-Cook, JM Sherman, CB Brachmann, RC Allshire, JD Boeke, ... Molecular biology of the cell 10 (10), 3171-3186, 1999 | 92 | 1999 |
| Drosophila Bcl‐2 proteins participate in stress‐induced apoptosis, but are not required for normal development EA Sevrioukov, J Burr, EW Huang, HH Assi, JP Monserrate, DC Purves, ... Genesis 45 (4), 184-193, 2007 | 88 | 2007 |
| Andecaliximab/GS-5745 alone and combined with mFOLFOX6 in advanced gastric and gastroesophageal junction adenocarcinoma: results from a phase I study MA Shah, A Starodub, S Sharma, J Berlin, M Patel, ZA Wainberg, ... Clinical Cancer Research 24 (16), 3829-3837, 2018 | 87 | 2018 |
| Bcl-2 proteins and autophagy regulate mitochondrial dynamics during programmed cell death in the Drosophila ovary EA Tanner, TA Blute, CB Brachmann, K McCall Development 138 (2), 327-338, 2011 | 83 | 2011 |
| A critical proteolytic cleavage site near the C terminus of the yeast retrotransposon Ty1 Gag protein GV Merkulov, KM Swiderek, CB Brachmann, JD Boeke Journal of virology 70 (8), 5548-5556, 1996 | 74 | 1996 |
