| Stoichiometry and turnover in single, functioning membrane protein complexes MC Leake, JH Chandler, GH Wadhams, F Bai, RM Berry, JP Armitage Nature 443 (7109), 355-358, 2006 | 674 | 2006 |
| Stoichiometry and architecture of active DNA replication machinery in Escherichia coli R Reyes-Lamothe, DJ Sherratt, MC Leake Science 328 (5977), 498-501, 2010 | 461 | 2010 |
| Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts I Makarenko, CA Opitz, MC Leake, C Neagoe, M Kulke, JK Gwathmey, ... Circulation research 95 (7), 708-716, 2004 | 428 | 2004 |
| Direct observation of steps in rotation of the bacterial flagellar motor Y Sowa, AD Rowe, MC Leake, T Yakushi, M Homma, A Ishijima, RM Berry Nature 437 (7060), 916-919, 2005 | 374 | 2005 |
| Single-molecule fluorescence microscopy review: shedding new light on old problems S Shashkova, MC Leake Bioscience reports 37 (4), BSR20170031, 2017 | 351 | 2017 |
| The maximum number of torque-generating units in the flagellar motor of Escherichia coli is at least 11 SW Reid, MC Leake, JH Chandler, CJ Lo, JP Armitage, RM Berry Proceedings of the National Academy of Sciences 103 (21), 8066-8071, 2006 | 320 | 2006 |
| ATP-dependent dynamic protein aggregation regulates bacterial dormancy depth critical for antibiotic tolerance Y Pu, Y Li, X Jin, T Tian, Q Ma, Z Zhao, S Lin, Z Chen, B Li, G Yao, ... Molecular cell 73 (1), 143-156. e4, 2019 | 293 | 2019 |
| In vivo architecture and action of bacterial structural maintenance of chromosome proteins A Badrinarayanan, R Reyes-Lamothe, S Uphoff, MC Leake, DJ Sherratt Science 338 (6106), 528-531, 2012 | 265 | 2012 |
| Variable stoichiometry of the TatA component of the twin-arginine protein transport system observed by in vivo single-molecule imaging MC Leake, NP Greene, RM Godun, T Granjon, G Buchanan, S Chen, ... Proceedings of the National Academy of Sciences 105 (40), 15376-15381, 2008 | 230 | 2008 |
| Developmentally regulated switching of titin size alters myofibrillar stiffness in the perinatal heart CA Opitz, MC Leake, I Makarenko, V Benes, WA Linke Circulation research 94 (7), 967-975, 2004 | 228 | 2004 |
| Single-molecule techniques in biophysics: a review of the progress in methods and applications H Miller, Z Zhou, J Shepherd, AJM Wollman, MC Leake Reports on Progress in Physics 81 (2), 024601, 2017 | 214 | 2017 |
| Association of the chaperone αB-crystallin with titin in heart muscle B Bullard, C Ferguson, A Minajeva, MC Leake, M Gautel, D Labeit, L Ding, ... Journal of Biological Chemistry 279 (9), 7917-7924, 2004 | 206 | 2004 |
| From Animaculum to single molecules: 300 years of the light microscope AJM Wollman, R Nudd, EG Hedlund, MC Leake Open biology 5 (4), 150019, 2015 | 203 | 2015 |
| Signal-dependent turnover of the bacterial flagellar switch protein FliM NJ Delalez, GH Wadhams, G Rosser, Q Xue, MT Brown, IM Dobbie, ... Proceedings of the national academy of sciences 107 (25), 11347-11351, 2010 | 202 | 2010 |
| Damped elastic recoil of the titin spring in myofibrils of human myocardium CA Opitz, M Kulke, MC Leake, C Neagoe, H Hinssen, RJ Hajjar, WA Linke Proceedings of the National Academy of Sciences 100 (22), 12688-12693, 2003 | 163 | 2003 |
| Frequent exchange of the DNA polymerase during bacterial chromosome replication TR Beattie, N Kapadia, E Nicolas, S Uphoff, AJM Wollman, MC Leake, ... Elife 6, e21763, 2017 | 133 | 2017 |
| Single-molecule in vivo imaging of bacterial respiratory complexes indicates delocalized oxidative phosphorylation I Llorente-Garcia, T Lenn, H Erhardt, OL Harriman, LN Liu, A Robson, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1837 (6), 811-824, 2014 | 120 | 2014 |
| The elasticity of single titin molecules using a two-bead optical tweezers assay MC Leake, D Wilson, M Gautel, RM Simmons Biophysical journal 87 (2), 1112-1135, 2004 | 118 | 2004 |
| Millisecond timescale slimfield imaging and automated quantification of single fluorescent protein molecules for use in probing complex biological processes M Plank, GH Wadhams, MC Leake Integrative Biology 1 (10), 602-612, 2009 | 115 | 2009 |
| Inferring diffusion in single live cells at the single-molecule level A Robson, K Burrage, MC Leake Philosophical Transactions of the Royal Society B: Biological Sciences 368 …, 2013 | 113 | 2013 |
Wolfgang A LinkeProfessor of Physiology, University of MünsterEmail verificata su uni-muenster.de
