Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity G Wang, RD Chow, Z Bai, L Zhu, Y Errami, X Dai, MB Dong, L Ye, ... Nature Immunology 20 (11), 1494-1505, 2019 | 105 | 2019 |
Biomarker MicroRNAs for diagnosis, prognosis and treatment of hepatocellular carcinoma: a functional survey and comparison S Shen, Y Lin, X Yuan, L Shen, J Chen, L Chen, L Qin, B Shen Scientific reports 6 (1), 38311, 2016 | 99 | 2016 |
Computer-aided biomarker discovery for precision medicine: data resources, models and applications Y Lin, F Qian, L Shen, F Chen, J Chen, B Shen Briefings in bioinformatics 20 (3), 952-975, 2019 | 79 | 2019 |
Knowledge-guided bioinformatics model for identifying autism spectrum disorder diagnostic MicroRNA biomarkers L Shen, Y Lin, Z Sun, X Yuan, L Chen, B Shen Scientific reports 6 (1), 39663, 2016 | 59 | 2016 |
In vivo profiling of metastatic double knockouts through CRISPR–Cpf1 screens RD Chow, G Wang, L Ye, A Codina, HR Kim, L Shen, MB Dong, Y Errami, ... Nature methods 16 (5), 405-408, 2019 | 58 | 2019 |
Identification of biomarker microRNAs for predicting the response of colorectal cancer to neoadjuvant chemoradiotherapy based on microRNA regulatory network Y Zhu, Q Peng, Y Lin, L Zou, P Shen, F Chen, M Min, L Shen, J Chen, ... Oncotarget 8 (2), 2233, 2016 | 48 | 2016 |
Biomarker microRNAs for prostate cancer metastasis: screened with a network vulnerability analysis model Y Lin, F Chen, L Shen, X Tang, C Du, Z Sun, H Ding, J Chen, B Shen Journal of translational medicine 16, 1-16, 2018 | 45 | 2018 |
Natural products for the prevention and control of the COVID-19 pandemic: sustainable bioresources RK Singla, X He, H Chopra, C Tsagkaris, L Shen, MA Kamal, B Shen Frontiers in Pharmacology 12, 758159, 2021 | 38 | 2021 |
The fourth scientific discovery paradigm for precision medicine and healthcare: challenges ahead L Shen, J Bai, J Wang, B Shen Precision Clinical Medicine 4 (2), 80-84, 2021 | 33 | 2021 |
MiRNA-BD: an evidence-based bioinformatics model and software tool for microRNA biomarker discovery Y Lin, W Wu, Z Sun, L Shen, B Shen RNA biology 15 (8), 1093-1105, 2018 | 28 | 2018 |
Altered nitric oxide induced by gut microbiota reveals the connection between central precocious puberty and obesity Y Li, L Shen, C Huang, X Li, J Chen, SC Li, B Shen Clinical and translational medicine 11 (2), 2021 | 27 | 2021 |
Physiological informatics: Collection and analyses of data from wearable sensors and smartphone for healthcare J Bai, L Shen, H Sun, B Shen Healthcare and Big Data Management, 17-37, 2017 | 26 | 2017 |
Convergent identification and interrogation of tumor-intrinsic factors that modulate cancer immunity in vivo A Codina, PA Renauer, G Wang, RD Chow, JJ Park, H Ye, K Zhang, ... Cell systems 8 (2), 136-151. e7, 2019 | 21 | 2019 |
MiR‐378a‐3p as a putative biomarker for hepatocellular carcinoma diagnosis and prognosis: Computational screening with experimental validation F Qian, J Wang, Y Wang, Q Gao, W Yan, Y Lin, L Shen, Y Xie, X Jiang, ... Clinical and Translational Medicine 11 (2), e307, 2021 | 20 | 2021 |
CMBD: a manually curated cancer metabolic biomarker knowledge database J Chen, X Liu, L Shen, Y Lin, B Shen Database 2021, baaa094, 2021 | 16 | 2021 |
Data-driven microbiota biomarker discovery for personalized drug therapy of cardiovascular disease L Shen, K Shen, J Bai, J Wang, RK Singla, B Shen Pharmacological Research 161, 105225, 2020 | 11 | 2020 |
Systems health: a transition from disease management toward health promotion L Shen, B Ye, H Sun, Y Lin, H van Wietmarschen, B Shen Healthcare and Big Data Management, 149-164, 2017 | 11 | 2017 |
NDDVD: an integrated and manually curated Neurodegenerative Diseases Variation Database Y Yang, C Xu, X Liu, C Xu, Y Zhang, L Shen, M Vihinen, B Shen Database 2018, bay018, 2018 | 9 | 2018 |
Understanding amino acid mutations in hepatitis B virus proteins for rational design of vaccines and drugs K Shen, L Shen, J Wang, Z Jiang, B Shen Advances in Protein Chemistry and Structural Biology 99, 131-153, 2015 | 9 | 2015 |
Translational informatics for natural products as antidepressant agents RK Singla, S Joon, L Shen, B Shen Frontiers in Cell and Developmental Biology 9, 738838, 2022 | 5 | 2022 |