| Landscape of genetic lesions in 944 patients with myelodysplastic syndromes T Haferlach, Y Nagata, V Grossmann, Y Okuno, U Bacher, G Nagae, ... Leukemia 28 (2), 241-247, 2014 | 1736 | 2014 |
| Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia T Schenk, WC Chen, S Göllner, L Howell, L Jin, K Hebestreit, HU Klein, ... Nature medicine 18 (4), 605-611, 2012 | 711 | 2012 |
| Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms C Polprasert, I Schulze, MA Sekeres, H Makishima, B Przychodzen, ... Cancer cell 27 (5), 658-670, 2015 | 478 | 2015 |
| A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease S Mostafavi, C Gaiteri, SE Sullivan, CC White, S Tasaki, J Xu, M Taga, ... Nature Neuroscience 21 (6), 811, 2018 | 438 | 2018 |
| An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome B Ng, CC White, HU Klein, SK Sieberts, C McCabe, E Patrick, J Xu, L Yu, ... Nature neuroscience 20 (10), 1418-1426, 2017 | 427 | 2017 |
| A multi-omic atlas of the human frontal cortex for aging and Alzheimer’s disease research PL De Jager, Y Ma, C McCabe, J Xu, BN Vardarajan, D Felsky, HU Klein, ... Scientific data 5 (1), 1-13, 2018 | 412 | 2018 |
| Next-generation sequencing technology reveals a characteristic pattern of molecular mutations in 72.8% of chronic myelomonocytic leukemia by detecting frequent alterations in … A Kohlmann, V Grossmann, HU Klein, S Schindela, T Weiss, B Kazak, ... Journal of clinical oncology 28 (24), 3858-3865, 2010 | 352 | 2010 |
| Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype V Grossmann, E Tiacci, AB Holmes, A Kohlmann, MP Martelli, W Kern, ... Blood, The Journal of the American Society of Hematology 118 (23), 6153-6163, 2011 | 305 | 2011 |
| Tau activates transposable elements in Alzheimer’s disease C Guo, HH Jeong, YC Hsieh, HU Klein, DA Bennett, PL De Jager, Z Liu, ... Cell Reports 23 (10), 2874-2880, 2018 | 272 | 2018 |
| Detection of significantly differentially methylated regions in targeted bisulfite sequencing data K Hebestreit, M Dugas, HU Klein Bioinformatics 29 (13), 1647-1653, 2013 | 262 | 2013 |
| Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia S Göllner, T Oellerich, S Agrawal-Singh, T Schenk, HU Klein, C Rohde, ... Nature medicine 23 (1), 69-78, 2017 | 235 | 2017 |
| Meta-analysis of the Alzheimer’s disease human brain transcriptome and functional dissection in mouse models YW Wan, R Al-Ouran, CG Mangleburg, TM Perumal, TV Lee, K Allison, ... Cell reports 32 (2), 2020 | 233 | 2020 |
| Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer’s human brains HU Klein, C McCabe, E Gjoneska, SE Sullivan, BJ Kaskow, A Tang, ... Nature neuroscience 22 (1), 37-46, 2019 | 220 | 2019 |
| Novel Alzheimer disease risk loci and pathways in African American individuals using the African genome resources panel: a meta-analysis BW Kunkle, M Schmidt, HU Klein, AC Naj, KL Hamilton-Nelson, ... JAMA neurology 78 (1), 102-113, 2021 | 206 | 2021 |
| AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia F Zhou, Y Liu, C Rohde, C Pauli, D Gerloff, M Köhn, D Misiak, N Bäumer, ... Nature cell biology 19 (7), 844-855, 2017 | 162 | 2017 |
| Multilineage dysplasia (MLD) in acute myeloid leukemia (AML) correlates with MDS-related cytogenetic abnormalities and a prior history of MDS or MDS/MPN but has no independent … M Miesner, C Haferlach, U Bacher, T Weiss, K Macijewski, A Kohlmann, ... Blood, The Journal of the American Society of Hematology 116 (15), 2742-2751, 2010 | 155 | 2010 |
| Multilineage dysplasia has no impact on biologic, clinicopathologic, and prognostic features of AML with mutated nucleophosmin (NPM1) B Falini, K Macijewski, T Weiss, U Bacher, S Schnittger, W Kern, ... Blood, The Journal of the American Society of Hematology 115 (18), 3776-3786, 2010 | 147 | 2010 |
| Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells E Bolton-Gillespie, M Schemionek, HU Klein, S Flis, G Hoser, T Lange, ... Blood, The Journal of the American Society of Hematology 121 (20), 4175-4183, 2013 | 143 | 2013 |
| The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium … A Kohlmann, HU Klein, S Weissmann, S Bresolin, T Chaplin, H Cuppens, ... Leukemia 25 (12), 1840-1848, 2011 | 139 | 2011 |
| AML with translocation t (8; 16)(p11; p13) demonstrates unique cytomorphological, cytogenetic, molecular and prognostic features T Haferlach, A Kohlmann, HU Klein, C Ruckert, M Dugas, PM Williams, ... Leukemia 23 (5), 934-943, 2009 | 131 | 2009 |
Philip L. De JagerWeil-Granat Professor of Neurology at Columbia UniversityEmail verificata su cumc.columbia.edu