SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell stem cell 29 (2), 217-231. e8, 2022 | 199 | 2022 |
Liquid application method for time-resolved analyses by serial synchrotron crystallography P Mehrabi, EC Schulz, M Agthe, S Horrell, G Bourenkov, D von Stetten, ... Nature methods 16 (10), 979-982, 2019 | 104 | 2019 |
Recent structural insights into the function of copper nitrite reductases S Horrell, D Kekilli, RW Strange, MA Hough Metallomics 9 (11), 1470-1482, 2017 | 67 | 2017 |
Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal S Horrell, SV Antonyuk, RR Eady, SS Hasnain, MA Hough, RW Strange IUCrJ 3 (4), 271-281, 2016 | 66 | 2016 |
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ... Science 382 (6671), eabo7201, 2023 | 58 | 2023 |
COVID moonshot: open science discovery of SARS-CoV-2 main protease inhibitors by combining crowdsourcing, high-throughput experiments, computational simulations, and machine … H Achdout, A Aimon, E Bar-David, GM Morris BioRxiv, 2020 | 54 | 2020 |
A microfluidic flow-focusing device for low sample consumption serial synchrotron crystallography experiments in liquid flow DCF Monteiro, M Vakili, J Harich, M Sztucki, SM Meier, S Horrell, I Josts, ... Journal of Synchrotron Radiation 26 (2), 406-412, 2019 | 44 | 2019 |
xia2. multiplex: a multi-crystal data-analysis pipeline RJ Gildea, J Beilsten-Edmands, D Axford, S Horrell, P Aller, J Sandy, ... Acta Crystallographica Section D: Structural Biology 78 (6), 752-769, 2022 | 43 | 2022 |
Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors COVID Moonshot Consortium, H Achdout, A Aimon, DS Alonzi, R Arbon, ... BioRxiv, 2020.10. 29.339317, 2020 | 39 | 2020 |
Photoreduction and validation of haem–ligand intermediate states in protein crystals by in situ single-crystal spectroscopy and diffraction D Kekilli, T Moreno-Chicano, AK Chaplin, S Horrell, FSN Dworkowski, ... IUCrJ 4 (3), 263-270, 2017 | 33 | 2017 |
Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases D Bellini, S Horrell, A Hutchin, CW Phippen, RW Strange, Y Cai, ... Scientific reports 7 (1), 42166, 2017 | 30 | 2017 |
Visualization of membrane protein crystals in lipid cubic phase using X-ray imaging AJ Warren, W Armour, D Axford, M Basham, T Connolley, DR Hall, ... Acta Crystallographica Section D: Biological Crystallography 69 (7), 1252-1259, 2013 | 30 | 2013 |
Enzyme catalysis captured using multiple structures from one crystal at varying temperatures S Horrell, D Kekilli, K Sen, RL Owen, FSN Dworkowski, SV Antonyuk, ... IUCrJ 5 (3), 283-292, 2018 | 29 | 2018 |
Making the invisible enemy visible TI Croll, K Diederichs, F Fischer, CD Fyfe, Y Gao, S Horrell, AP Joseph, ... Nature structural & molecular biology 28 (5), 404-408, 2021 | 23 | 2021 |
Homogeneous batch micro-crystallization of proteins from ammonium sulfate C Stohrer, S Horrell, S Meier, M Sans, D von Stetten, M Hough, ... Acta Crystallographica Section D: Structural Biology 77 (2), 194-204, 2021 | 19 | 2021 |
Active-site protein dynamics and solvent accessibility in native Achromobacter cycloclastes copper nitrite reductase K Sen, S Horrell, D Kekilli, CW Yong, TW Keal, H Atakisi, DW Moreau, ... IUCrJ 4 (4), 495-505, 2017 | 13 | 2017 |
Fixed Target Serial Data Collection at Diamond Light Source. S Horrell, D Axford, NE Devenish, A Ebrahim, MA Hough, DA Sherrell, ... Journal of Visualized Experiments 2021 (168), 2021 | 12 | 2021 |
3DBionotes Covid JR Macias, R Sanchez-Garcia, P Conesa, E Ramirez-Aportela, ... Bioinformatics 37 (22), 4258-4260, 2021 | 6 | 2021 |
An ultraviolet-driven rescue pathway for oxidative stress to eye lens protein human gamma-D crystallin JA Hill, Y Nyathi, S Horrell, D von Stetten, D Axford, RL Owen, ... Communications Chemistry 7 (1), 81, 2024 | 5 | 2024 |
Observation of Cation Chromophore Photoisomerization of a Fluorescent Protein Using Millisecond Synchrotron Serial Crystallography and Infrared Vibrational and Visible Spectroscopy JM Baxter, CDM Hutchison, K Maghlaoui, V Cordon-Preciado, ... The Journal of Physical Chemistry B 126 (45), 9288-9296, 2022 | 5 | 2022 |