Activating mutations in the epidermal growth factor receptor underlying responsiveness of non–small-cell lung cancer to gefitinib TJ Lynch, DW Bell, R Sordella, S Gurubhagavatula, RA Okimoto, ... New England Journal of Medicine 350 (21), 2129-2139, 2004 | 14173 | 2004 |
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development M Okano, DW Bell, DA Haber, E Li Cell 99 (3), 247-257, 1999 | 7648 | 1999 |
Anaplastic lymphoma kinase inhibition in non–small-cell lung cancer EL Kwak, YJ Bang, DR Camidge, AT Shaw, B Solomon, RG Maki, SHI Ou, ... New England Journal of Medicine 363 (18), 1693-1703, 2010 | 5491 | 2010 |
Isolation of rare circulating tumour cells in cancer patients by microchip technology S Nagrath, LV Sequist, S Maheswaran, DW Bell, D Irimia, L Ulkus, ... Nature 450 (7173), 1235-1239, 2007 | 4486 | 2007 |
Epidermal growth factor receptor mutations in lung cancer SV Sharma, DW Bell, J Settleman, DA Haber Nature Reviews Cancer 7 (3), 169-181, 2007 | 3836 | 2007 |
Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells W Yang, J Soares, P Greninger, EJ Edelman, H Lightfoot, S Forbes, ... Nucleic acids research 41 (D1), D955-D961, 2012 | 3294 | 2012 |
Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition M Yu, A Bardia, BS Wittner, SL Stott, ME Smas, DT Ting, SJ Isakoff, ... science 339 (6119), 580-584, 2013 | 2731 | 2013 |
Systematic identification of genomic markers of drug sensitivity in cancer cells MJ Garnett, EJ Edelman, SJ Heidorn, CD Greenman, A Dastur, KW Lau, ... Nature 483 (7391), 570-575, 2012 | 2640 | 2012 |
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization M Meyerson, CM Counter, EN Eaton, LW Ellisen, P Steiner, SD Caddle, ... cell 90 (4), 785-795, 1997 | 2604 | 1997 |
Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis N Aceto, A Bardia, DT Miyamoto, MC Donaldson, BS Wittner, JA Spencer, ... Cell 158 (5), 1110-1122, 2014 | 2596 | 2014 |
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus KM Call, T Glaser, CY Ito, AJ Buckler, J Pelletier, DA Haber, EA Rose, ... Cell 60 (3), 509-520, 1990 | 2473 | 1990 |
Detection of Mutations in EGFR in Circulating Lung-Cancer Cells S Maheswaran, LV Sequist, S Nagrath, L Ulkus, B Brannigan, CV Collura, ... New England Journal of Medicine 359 (4), 366-377, 2008 | 2158 | 2008 |
Gefitinib-Sensitizing EGFR Mutations in Lung Cancer Activate Anti-Apoptotic Pathways R Sordella, DW Bell, DA Haber, J Settleman Science 305 (5687), 1163-1167, 2004 | 2095 | 2004 |
Isolation of circulating tumor cells using a microvortex-generating herringbone-chip SL Stott, CH Hsu, DI Tsukrov, M Yu, DT Miyamoto, BA Waltman, ... Proceedings of the National Academy of Sciences 107 (43), 18392-18397, 2010 | 1994 | 2010 |
A landscape of pharmacogenomic interactions in cancer F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ... Cell 166 (3), 740-754, 2016 | 1883 | 2016 |
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway VS Viswanathan, MJ Ryan, HD Dhruv, S Gill, OM Eichhoff, ... Nature 547 (7664), 453-457, 2017 | 1552 | 2017 |
Circulating tumor cells: approaches to isolation and characterization M Yu, S Stott, M Toner, S Maheswaran, DA Haber Journal of Cell Biology 192 (3), 373-382, 2011 | 1346 | 2011 |
Heterozygous Germ Line hCHK2 Mutations in Li-Fraumeni Syndrome DW Bell, JM Varley, TE Szydlo, DH Kang, DCR Wahrer, KE Shannon, ... Science 286 (5449), 2528-2531, 1999 | 1241 | 1999 |
Inertial focusing for tumor antigen–dependent and–independent sorting of rare circulating tumor cells E Ozkumur, AM Shah, JC Ciciliano, BL Emmink, DT Miyamoto, E Brachtel, ... Science translational medicine 5 (179), 179ra47-179ra47, 2013 | 1214 | 2013 |
Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib EL Kwak, R Sordella, DW Bell, N Godin-Heymann, RA Okimoto, ... Proceedings of the National Academy of Sciences 102 (21), 7665-7670, 2005 | 1208 | 2005 |