Articoli con mandati relativi all'accesso pubblico - Thomas HelledayUlteriori informazioni
Non disponibili pubblicamente: 27
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Poly (ADP-Ribose) polymerase is hyperactivated in homologous recombination–defective cells
P Gottipati, B Vischioni, N Schultz, J Solomons, HE Bryant, T Djureinovic, ...
Cancer research 70 (13), 5389-5398, 2010
Mandati: Swedish Research Council, Cancer Research UK
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Targeting homologous recombination repair defects in cancer
B Evers, T Helleday, J Jonkers
Trends in pharmacological sciences 31 (8), 372-380, 2010
Mandati: Swedish Research Council
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Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies
N Herold, SG Rudd, L Ljungblad, K Sanjiv, IH Myrberg, CBJ Paulin, ...
Nature medicine 23 (2), 256-263, 2017
Mandati: US National Institutes of Health, German Research Foundation, Knut and Alice …
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Methylated DNA causes a physical block to replication forks independently of damage signalling, O6-methylguanine or DNA single-strand breaks and results in DNA damage
P Groth, S Ausländer, MM Majumder, N Schultz, F Johansson, ...
Journal of molecular biology 402 (1), 70-82, 2010
Mandati: Swedish Research Council, Cancer Research UK
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Drugging DNA repair
SP Jackson, T Helleday
Science 352 (6290), 1178-1179, 2016
Mandati: Cancer Research UK
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Lysophosphatidic acid receptor (LPAR) modulators: The current pharmacological toolbox
S Llona-Minguez, A Ghassemian, T Helleday
Progress in lipid research 58, 51-75, 2015
Mandati: Swedish Research Council
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Pathways controlling dNTP pools to maintain genome stability
SG Rudd, NCK Valerie, T Helleday
DNA repair 44, 193-204, 2016
Mandati: Swedish Research Council, European Commission
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PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites
O Mortusewicz, B Evers, T Helleday
Oncogene 35 (6), 761-770, 2016
Mandati: Swedish Research Council, Dutch Cancer Society
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CK2 phosphorylation of XRCC1 facilitates dissociation from DNA and single-strand break formation during base excision repair
CE Ström, O Mortusewicz, D Finch, JL Parsons, A Lagerqvist, ...
DNA repair 10 (9), 961-969, 2011
Mandati: Swedish Research Council, Cancer Research UK
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Amplifying tumour-specific replication lesions by DNA repair inhibitors–a new era in targeted cancer therapy
T Helleday
European journal of cancer 44 (7), 921-927, 2008
Mandati: Cancer Research UK
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Homologous recombination mediates cellular resistance and fraction size sensitivity to radiation therapy
N Somaiah, J Yarnold, A Lagerqvist, K Rothkamm, T Helleday
Radiotherapy and Oncology 108 (1), 155-161, 2013
Mandati: Swedish Research Council, Cancer Research UK, UK Medical Research Council
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Castration therapy of prostate cancer results in downregulation of HIF-1α levels
FLT Al-Ubaidi, N Schultz, L Egevad, T Granfors, T Helleday
International Journal of Radiation Oncology* Biology* Physics 82 (3), 1243-1248, 2012
Mandati: Swedish Research Council
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Putting poly (ADP-ribose) polymerase and other DNA repair inhibitors into clinical practice
T Helleday
Current Opinion in Oncology 25 (6), 609-614, 2013
Mandati: Swedish Research Council
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Piperazin-1-ylpyridazine derivatives are a novel class of human dCTP pyrophosphatase 1 inhibitors
S Llona-Minguez, A Hoglund, A Ghassemian, M Desroses, ...
Journal of medicinal chemistry 60 (10), 4279-4292, 2017
Mandati: Knut and Alice Wallenberg Foundation, Swedish Research Council, European …
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PrimPol breaks replication barriers
T Helleday
Nature structural & molecular biology 20 (12), 1348-1350, 2013
Mandati: Swedish Research Council, European Commission
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Human RECQL5 overcomes thymidine-induced replication stress
R Blundred, K Myers, T Helleday, ASH Goldman, HE Bryant
DNA repair 9 (9), 964-975, 2010
Mandati: Cancer Research UK
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Identification of triazolothiadiazoles as potent inhibitors of the dCTP pyrophosphatase 1
S Llona-Minguez, A Hoglund, E Wiita, I Almlof, A Mateus, ...
Journal of Medicinal Chemistry 60 (5), 2148-2154, 2017
Mandati: Knut and Alice Wallenberg Foundation, Swedish Research Council, European …
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DNA repair as treatment target
T Helleday
European journal of cancer 47, S333-S335, 2011
Mandati: Swedish Research Council
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Specific targeted gene repair using single-stranded DNA oligonucleotides at an endogenous locus in mammalian cells uses homologous recombination
J McLachlan, S Fernandez, T Helleday, HE Bryant
DNA repair 8 (12), 1424-1433, 2009
Mandati: Cancer Research UK
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Germline variation in the oxidative DNA repair genes NUDT1 and OGG1 is not associated with hereditary colorectal cancer or polyposis
P Mur, AS Jemth, L Bevc, N Amaral, M Navarro, R Valdés‐Mas, T Pons, ...
Human mutation 39 (9), 1214-1225, 2018
Mandati: Knut and Alice Wallenberg Foundation, Swedish Research Council, Government …
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