Christopher Liddle

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Michael DownesSenior Staff Scientist, Salk InsitituteEmail verificata su salk.edu
Ronald M EvansProfessor, Salk InstituteEmail verificata su salk.edu
Jacob GeorgeUniversity of Sydney, Westmead Millennium Institute, Westmead Hospital, University of QueenslandEmail verificata su sydney.edu.au
Martin WeltmanAssociate Professor of Medicine, Sydney Medical SchoolEmail verificata su wahs.nsw.gov.au
Alan R SaltielUCSDEmail verificata su ucsd.edu
Maryam AhmadianThe Salk Institute for Biological StudiesEmail verificata su salk.edu
Eiji YoshiharaLundquist Institute at Harbor-UCLA Medical Center/UCLA/Salk Institute/Kyoto UniversityEmail verificata su lundquist.org
Stephen ClarkeProfessor of Medicine, University of Sydney and Medical Oncologist, RNSH and Genesis CareEmail verificata su sydney.edu.au
Ning DingGenentechEmail verificata su gene.com
Mara ShermanOregon Health & Science UniversityEmail verificata su ohsu.edu
David BoothUniversity of SydneyEmail verificata su sydney.edu.au
Howard GurneyMacquarie University, Faculty of Medicine and Health SciencesEmail verificata su mq.edu.au
Weiwei FanSalk Institute for Biological StudiesEmail verificata su salk.edu
Jerrold OlefskyUniversity of California San DiegoEmail verificata su ucsd.edu
Mark DouglasUniversity of Sydney at Westmead HospitalEmail verificata su sydney.edu.au
Grant ParnellThe Westmead Institute for Medical Research, The University of SydneyEmail verificata su sydney.edu.au
Junichiro SonodaAmgenEmail verificata su amgen.com
Jenny GuntonWestmead Institute of Medical Research, WIMR, University of SydneyEmail verificata su sydney.edu.au
A/Prof David van der PoortenUniversity of Sydney at Westmead HospitalEmail verificata su sydney.edu.au
Johan W. JonkerProfessor, University Medical Center GroningenEmail verificata su umcg.nl

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Christopher Liddle

Emeritus Professor of Clinical Pharmacology and Hepatology, University of Sydney

Email verificata su sydney.edu.au - Home page

gene regulation bile acids nuclear receptors drug metabolism bioinformatics


Titolo Ordina per citazioni Ordina per anno Ordina per titolo	Citata da Citata da	Anno
PPARγ signaling and metabolism: the good, the bad and the future M Ahmadian, JM Suh, N Hah, C Liddle, AR Atkins, M Downes, RM Evans Nature medicine 19 (5), 557-566, 2013	2192	2013
NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome S Chitturi, S Abeygunasekera, GC Farrell, J Holmes-Walker, JM Hui, ... Hepatology 35 (2), 373-379, 2002	1562	2002
Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β H Cho, X Zhao, M Hatori, RT Yu, GD Barish, MT Lam, LW Chong, ... Nature 485 (7396), 123-127, 2012	1156	2012
Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy MH Sherman, TY Ruth, DD Engle, N Ding, AR Atkins, H Tiriac, ... Cell 159 (1), 80-93, 2014	1128	2014
Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands LB Moore, DJ Parks, SA Jones, RK Bledsoe, TG Consler, JB Stimmel, ... Journal of Biological Chemistry 275 (20), 15122-15127, 2000	1003	2000
The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module B Goodwin, E Hodgson, C Liddle Molecular pharmacology 56 (6), 1329-1339, 1999	824	1999
Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis MD Weltman, GC Farrell, P Hall, M Ingelman-Sundberg, C Liddle Hepatology 27 (1), 128-133, 1998	805	1998
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance S Fang, JM Suh, SM Reilly, E Yu, O Osborn, D Lackey, E Yoshihara, ... Nature medicine 21 (2), 159-165, 2015	780	2015
A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response N Ding, TY Ruth, N Subramaniam, MH Sherman, C Wilson, R Rao, ... Cell 153 (3), 601-613, 2013	671	2013
Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: a manifestation of lipotoxicity? S Chitturi, G Farrell, L Frost, A Kriketos, R Lin, C Liddle, D Samarasinghe, ... Hepatology 36 (2), 403-409, 2002	580	2002
Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation MD Weltman, GC Farrell, C Liddle Gastroenterology 111 (6), 1645-1653, 1996	514	1996
An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice SM Reilly, SH Chiang, SJ Decker, L Chang, M Uhm, MJ Larsen, JR Rubin, ... Nature medicine 19 (3), 313-321, 2013	471	2013
Regulation of drug-metabolizing enzymes and transporters in infection, inflammation, and cancer ET Morgan, KB Goralski, M Piquette-Miller, KW Renton, GR Robertson, ... Drug Metabolism and Disposition 36 (2), 205-216, 2008	450	2008
Pre-translational regulation of cytochrome P450 genes is responsible for disease-specific changes of individual P450 enzymes among patients with cirrhosis J George, C Liddle, M Murray, K Byth, GC Farrell Biochemical pharmacology 49 (7), 873-881, 1995	390	1995
FXR regulates intestinal cancer stem cell proliferation T Fu, S Coulter, E Yoshihara, TG Oh, S Fang, F Cayabyab, Q Zhu, ... Cell 176 (5), 1098-1112. e18, 2019	386	2019
Depletion of fat-resident T_reg cells prevents age-associated insulin resistance SP Bapat, J Myoung Suh, S Fang, S Liu, Y Zhang, A Cheng, C Zhou, ... Nature 528 (7580), 137-141, 2015	337	2015
Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes NH Uhlenhaut, GD Barish, TY Ruth, M Downes, M Karunasiri, C Liddle, ... Molecular cell 49 (1), 158-171, 2013	311	2013
Transcriptional regulation of the human CYP3A4gene by the constitutive androstane receptor B Goodwin, E Hodgson, DJ D'Costa, GR Robertson, C Liddle Molecular pharmacology 62 (2), 359-365, 2002	310	2002
Lean NAFLD: a distinct entity shaped by differential metabolic adaptation F Chen, S Esmaili, GB Rogers, E Bugianesi, S Petta, G Marchesini, ... Hepatology 71 (4), 1213-1227, 2020	307	2020
HFE mutations, hepatic iron, and fibrosis: ethnic‐specific association of NASH with C282Y but not with fibrotic severity S Chitturi, M Weltman, GC Farrell, D McDonald, C Liddle, ... Hepatology 36 (1), 142-149, 2002	296	2002

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