A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv (3)(q21; q26) by activating EVI1 expression H Yamazaki, M Suzuki, A Otsuki, R Shimizu, EH Bresnick, JD Engel, ... Cancer cell 25 (4), 415-427, 2014 | 270 | 2014 |
3.5 KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome S Tadaka, F Katsuoka, M Ueki, K Kojima, S Makino, S Saito, A Otsuki, ... Human Genome Variation 6 (1), 28, 2019 | 149 | 2019 |
Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation K Tsuchida, T Tsujita, M Hayashi, A Ojima, N Keleku-Lukwete, F Katsuoka, ... Free Radical Biology and Medicine 103, 236-247, 2017 | 146 | 2017 |
jMorp updates in 2020: large enhancement of multi-omics data resources on the general Japanese population S Tadaka, E Hishinuma, S Komaki, IN Motoike, J Kawashima, D Saigusa, ... Nucleic acids research 49 (D1), D536-D544, 2021 | 130 | 2021 |
Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation N Keleku-Lukwete, M Suzuki, A Otsuki, K Tsuchida, S Katayama, ... Proceedings of the National Academy of Sciences 112 (39), 12169-12174, 2015 | 108 | 2015 |
Unique cistrome defined as CsMBE is strictly required for Nrf2-sMaf heterodimer function in cytoprotection A Otsuki, M Suzuki, F Katsuoka, K Tsuchida, H Suda, M Morita, R Shimizu, ... Free Radical Biology and Medicine 91, 45-57, 2016 | 65 | 2016 |
Overview of redox regulation by Keap1–Nrf2 system in toxicology and cancer M Suzuki, A Otsuki, N Keleku-Lukwete, M Yamamoto Current Opinion in Toxicology 1, 29-36, 2016 | 64 | 2016 |
Cis-element architecture of Nrf2–sMaf heterodimer binding sites and its relation to diseases A Otsuki, M Yamamoto Archives of pharmacal research 43 (3), 275-285, 2020 | 56 | 2020 |
Construction and integration of three de novo Japanese human genome assemblies toward a population-specific reference J Takayama, S Tadaka, K Yano, F Katsuoka, C Gocho, T Funayama, ... Nature communications 12 (1), 1-14, 2021 | 54 | 2021 |
GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis S Katayama, M Suzuki, A Yamaoka, N Keleku-Lukwete, F Katsuoka, ... Blood, The Journal of the American Society of Hematology 130 (7), 908-919, 2017 | 49 | 2017 |
Genome analyses for the Tohoku Medical Megabank Project towards establishment of personalized healthcare J Yasuda, K Kinoshita, F Katsuoka, I Danjoh, M Sakurai-Yageta, ... The journal of biochemistry 165 (2), 139-158, 2019 | 44 | 2019 |
Nrf2 contributes to the weight gain of mice during space travel T Suzuki, A Uruno, A Yumoto, K Taguchi, M Suzuki, N Harada, R Ryoke, ... Communications biology 3 (1), 1-14, 2020 | 33 | 2020 |
Direct and specific functional evaluation of the Nrf2 and MafG heterodimer by introducing a tethered dimer into small Maf-deficient cells F Katsuoka, A Otsuki, M Takahashi, S Ito, M Yamamoto Molecular and cellular biology 39 (20), e00273-19, 2019 | 30 | 2019 |
jMorp: Japanese Multi-Omics Reference Panel update report 2023 S Tadaka, J Kawashima, E Hishinuma, S Saito, Y Okamura, A Otsuki, ... Nucleic Acids Research, gkad978, 2023 | 27 | 2023 |
Japonica Array NEO with increased genome-wide coverage and abundant disease risk SNPs M Sakurai-Yageta, K Kumada, C Gocho, S Makino, A Uruno, S Tadaka, ... The Journal of Biochemistry 170 (3), 399-410, 2021 | 23 | 2021 |
Japonica Array NEO with increased genome-wide coverage and abundant disease risk SNPs M Sakurai-Yageta, K Kumada, C Gocho, S Makino, A Uruno, S Tadaka, ... Journal of Biochemistry 170 (3), 399-410, 2021 | 23 | 2021 |
Nrf2 activation in myeloid cells and endothelial cells differentially mitigates sickle cell disease pathology in mice N Keleku-Lukwete, M Suzuki, H Panda, A Otsuki, F Katsuoka, R Saito, ... Blood advances 3 (8), 1285-1297, 2019 | 21 | 2019 |
The β-TrCP-Mediated Pathway Cooperates with the Keap1-Mediated Pathway in Nrf2 Degradation In Vivo A Kuga, K Tsuchida, H Panda, M Horiuchi, A Otsuki, K Taguchi, ... Molecular and cellular biology 42 (7), e00563-21, 2022 | 15 | 2022 |
Target Gene Diversity of the Nrf1-MafG Transcription Factor Revealed by a Tethered Heterodimer F Katsuoka, A Otsuki, N Hatanaka, H Okuyama, M Yamamoto Molecular and cellular biology 42 (3), e00520-21, 2022 | 15 | 2022 |
Gata3 Hypomorphic Mutant Mice Rescued with a Yeast Artificial Chromosome Transgene Suffer a Glomerular Mesangial Cell Defect T Moriguchi, L Yu, A Otsuki, K Ainoya, KC Lim, M Yamamoto, JD Engel Molecular and cellular biology 36 (17), 2272-2281, 2016 | 15 | 2016 |