Articoli con mandati relativi all'accesso pubblico - Em. Prof. Brian J SmithUlteriori informazioni
Non disponibili pubblicamente: 7
Stabilizing the pro-apoptotic BimBH3 helix (BimSAHB) does not necessarily enhance affinity or biological activity
T Okamoto, K Zobel, A Fedorova, C Quan, H Yang, WJ Fairbrother, ...
ACS Chemical Biology, 2012
Mandati: National Health and Medical Research Council, Australia
BAK core dimers bind lipids and can be bridged by them
AD Cowan, NA Smith, JJ Sandow, EA Kapp, YH Rustam, JM Murphy, ...
Nature Structural & Molecular Biology, 1-8, 2020
Mandati: Australian Research Council, National Health and Medical Research Council …
Structural insights into the protease-like antigen Plasmodium falciparum SERA5 and its noncanonical active-site serine
AN Hodder, RL Malby, OB Clarke, WD Fairlie, PM Colman, BS Crabb, ...
Journal of molecular biology 392 (1), 154-165, 2009
Mandati: Howard Hughes Medical Institute
Predicting aqueous solubility by QSPR modeling
N Meftahi, ML Walker, BJ Smith
Journal of Molecular Graphics and Modelling, 107901, 2021
Mandati: Australian Research Council
Anticonvulsant Met-Enkephalin Analogues Containing Backbone Spacers Reveal Alternative Non-Opioid Signaling in the Brain
HK Lee, MD Smith, BJ Smith, J Grussendorf, L Xu, RJ Gillies, HS White, ...
ACS Chemical Biology 4 (8), 659-671, 2009
Mandati: US National Institutes of Health
Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-XL and BCL-2
MJ Roy, A Vom, T Okamoto, BJ Smith, RW Birkinshaw, H Yang, H Abdo, ...
Journal of Medicinal Chemistry, 2021
Mandati: Australian Research Council, National Health and Medical Research Council …
Optimization of Benzothiazole and Thiazole Hydrazones as Inhibitors of Schistosome BCL-2
W Nguyen, EF Lee, M Evangelista, M Lee, TJ Harris, PM Colman, ...
ACS Infectious Diseases, 2021
Mandati: Swiss National Science Foundation, National Health and Medical Research …
Disponibili pubblicamente: 68
Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis
PE Czabotar, D Westphal, G Dewson, S Ma, C Hockings, WD Fairlie, ...
Cell 152 (3), 519-531, 2013
Mandati: Australian Research Council, National Health and Medical Research Council …
A newly discovered protein export machine in malaria parasites
TF de Koning-Ward, PR Gilson, JA Boddey, M Rug, BJ Smith, ...
Nature 459 (7249), 945-949, 2009
Mandati: US National Institutes of Health, Howard Hughes Medical Institute
How insulin engages its primary binding site on the insulin receptor
JG Menting, J Whittaker, MB Margetts, LJ Whittaker, GKW Kong, BJ Smith, ...
Nature 493 (7431), 241-245, 2013
Mandati: US National Institutes of Health, National Health and Medical Research …
Structure-guided design of a selective BCL-XL inhibitor
G Lessene, PE Czabotar, BE Sleebs, K Zobel, KN Lowes, JM Adams, ...
Nature chemical biology 9 (6), 390-397, 2013
Mandati: Australian Research Council, National Health and Medical Research Council …
Discovery of a Potent and Selective BCL-XL Inhibitor with In Vivo Activity
ZF Tao, L Hasvold, L Wang, X Wang, AM Petros, CH Park, ER Boghaert, ...
ACS medicinal chemistry letters 5 (10), 1088-1093, 2014
Mandati: Australian Research Council, National Health and Medical Research Council …
Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax
J Gruszczyk, U Kanjee, LJ Chan, S Menant, B Malleret, NTY Lim, ...
Science 359 (6371), 48-55, 2018
Mandati: US National Institutes of Health, Howard Hughes Medical Institute …
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
EJ Petrie, JJ Sandow, AV Jacobsen, BJ Smith, MDW Griffin, IS Lucet, ...
Nature communications 9 (1), 2422, 2018
Mandati: Australian Research Council, National Health and Medical Research Council …
High‐Resolution Structural Characterization of a Helical α/β‐Peptide Foldamer Bound to the Anti‐Apoptotic Protein Bcl‐xL
EF Lee, JD Sadowsky, BJ Smith, PE Czabotar, KJ Peterson‐Kaufman, ...
Angewandte Chemie International Edition 48 (24), 4318-4322, 2009
Mandati: US National Institutes of Health
Protective hinge in insulin opens to enable its receptor engagement
JG Menting, Y Yang, SJ Chan, NB Phillips, BJ Smith, J Whittaker, ...
Proceedings of the National Academy of Sciences 111 (33), E3395-E3404, 2014
Mandati: US National Institutes of Health, National Health and Medical Research …
Evaluation of Diverse α/β Backbone Patterns for Functional α-Helix Mimicry: Analogues of the Bim BH3 Domain
MD Boersma, HS Haase, KJ Peterson-Kaufman, EF Lee, OB Clarke, ...
Journal of the American Chemical Society, 2012
Mandati: US National Institutes of Health
Engineering a stable and selective peptide blocker of the Kv1. 3 channel in T lymphocytes
MW Pennington, C Beeton, CA Galea, BJ Smith, V Chi, KP Monaghan, ...
Molecular pharmacology 75 (4), 762-773, 2009
Mandati: US National Institutes of Health
Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites
BE Sleebs, S Lopaticki, DS Marapana, MT O'Neill, P Rajasekaran, ...
Mandati: Howard Hughes Medical Institute, Australian Research Council, National …
α/β-Peptide Foldamers Targeting Intracellular Protein–Protein Interactions with Activity in Living Cells
JW Checco, EF Lee, M Evangelista, NJ Sleebs, K Rogers, ...
Journal of the American Chemical Society, 2015
Mandati: US National Institutes of Health, National Health and Medical Research …
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