Hao Wu

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Judy LiebermanBoston Children's Hospital, Harvard Medical SchoolEmail verificata su childrens.harvard.edu
Jianbin RuanUniversity of Connecticut Health CenterEmail verificata su uchc.edu
Qian YinFlorida State UniversityEmail verificata su bio.fsu.edu
Venkat Giri MagupalliLindsley F. Kimball Research Institute / New York Blood Center EnterpriseEmail verificata su nybc.org
Qi QiaoMorphic Therapeutic, Inc.Email verificata su morphictx.com
Alvin LuTango Therapeutics LLC, Harvard UniversityEmail verificata su alumni.harvard.edu
Jonathan C KaganHarvard Medical School/Boston Children's HospitalEmail verificata su childrens.harvard.edu
Jixi LiFudan University, ChinaEmail verificata su fudan.edu.cn
Edward H. EgelmanProfessor of Biochemistry and Molecular Genetics, University of VirginiaEmail verificata su virginia.edu
Johanna NapetschnigRegeneron Pharmaceuticals IncEmail verificata su regeneron.com
Katherine FitzgeraldProfessor of Medicine, University of Massachusetts Medical SchoolEmail verificata su umassmed.edu
Gunes BozkurtPostdoctoral fellow, Boston Childrens HospitalEmail verificata su bzh.uni-heidelberg.de
Zoltan MaligaLaboratory of Systems Pharmacology, Harvard Medical SchoolEmail verificata su hms.harvard.edu
Richard SiegelNovartis Institutes of BioMedical ResearchEmail verificata su novartis.com
Ann McDermottDepartment of Chemistry, Columbia UniversityEmail verificata su columbia.edu
Heng Ru (茹衡)Life Sciences Institute, Zhejiang UniversityEmail verificata su zju.edu.cn
Liang TongDepartment of Biological Sciences, Columbia UniversityEmail verificata su columbia.edu
Liman ZhangOregon Health and Science UniversityEmail verificata su ohsu.edu
Francis ChanProfessor, Duke University School of MedicineEmail verificata su duke.edu
Walter KellerProfessor of Structural Biology, University of GrazEmail verificata su uni-graz.at

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Hao Wu

Asa and Patricia Springer Professor, Boston Children's Hospital and Harvard Medical School

Email verificata su crystal.harvard.edu - Home page

Structural biology innate immunity adaptive immunity therapeutics


Titolo Ordina per citazioni Ordina per anno Ordina per titolo	Citata da Citata da	Anno
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores X Liu, Z Zhang, J Ruan, Y Pan, VG Magupalli, H Wu, J Lieberman Nature 535 (7610), 153-158, 2016	2788	2016
ABAD directly links Aß to mitochondrial toxicity in Alzheimer's disease JW Lustbader, M Cirilli, C Lin, HW Xu, K Takuma, N Wang, C Caspersen, ... Science 304 (5669), 448-452, 2004	1626	2004
Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug H Wu, E Esteve, V Tremaroli, MT Khan, R Caesar, L Mannerås-Holm, ... Nature medicine 23 (7), 850-858, 2017	1537	2017
Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes A Lu, VG Magupalli, J Ruan, Q Yin, MK Atianand, MR Vos, GF Schröder, ... Cell 156 (6), 1193-1206, 2014	1324	2014
Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling SC Lin, YC Lo, H Wu Nature 465 (7300), 885-890, 2010	1288	2010
The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis J Li, T McQuade, AB Siemer, J Napetschnig, K Moriwaki, YS Hsiao, ... Cell 150 (2), 339-350, 2012	1279	2012
Gasdermin E suppresses tumour growth by activating anti-tumour immunity Z Zhang, Y Zhang, S Xia, Q Kong, S Li, X Liu, C Junqueira, KF Meza-Sosa, ... Nature 579 (7799), 415-420, 2020	1196	2020
Molecular basis of NF-κB signaling J Napetschnig, H Wu Annual review of biophysics 42 (1), 443-468, 2013	1151	2013
The pore-forming protein gasdermin D regulates interleukin-1 secretion from living macrophages CL Evavold, J Ruan, Y Tan, S Xia, H Wu, JC Kagan Immunity 48 (1), 35-44. e6, 2018	1051	2018
Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death P Orning, D Weng, K Starheim, D Ratner, Z Best, B Lee, A Brooks, S Xia, ... Science 362 (6418), 1064-1069, 2018	846	2018
Distinct molecular mechanism for initiating TRAF6 signalling H Ye, JR Arron, B Lamothe, M Cirilli, T Kobayashi, NK Shevde, D Segal, ... Nature 418 (6896), 443-447, 2002	811	2002
FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation JJ Hu, X Liu, S Xia, Z Zhang, Y Zhang, J Zhao, J Ruan, X Luo, X Lou, ... Nature immunology 21 (7), 736-745, 2020	758	2020
All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction JY Chung, YC Park, H Ye, H Wu Journal of cell science 115 (4), 679-688, 2002	753	2002
Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain Y Huang, YC Park, RL Rich, D Segal, DG Myszka, H Wu Cell 104 (5), 781-790, 2001	749	2001
The three-dimensional structure of canine parvovirus and its functional implications J Tsao, MS Chapman, M Agbandje, W Keller, K Smith, H Wu, M Luo, ... Science 251 (5000), 1456-1464, 1991	682	1991
Microbially produced imidazole propionate impairs insulin signaling through mTORC1 A Koh, A Molinaro, M Ståhlman, MT Khan, C Schmidt, L Mannerås-Holm, ... Cell 175 (4), 947-961. e17, 2018	652	2018
Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome H Sharif, L Wang, WL Wang, VG Magupalli, L Andreeva, Q Qiao, ... Nature 570 (7761), 338-343, 2019	629	2019
The death domain superfamily in intracellular signaling of apoptosis and inflammation HH Park, YC Lo, SC Lin, L Wang, JK Yang, H Wu Annu. Rev. Immunol. 25 (1), 561-586, 2007	629	2007
Structure of human chorionic gonadotropin at 2.6 Å resolution from MAD analysis of the selenomethionyl protein H Wu, JW Lustbader, Y Liu, RE Canfield, WA Hendrickson Structure 2 (6), 545-558, 1994	601	1994
An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells I Zanoni, Y Tan, M Di Gioia, A Broggi, J Ruan, J Shi, CA Donado, F Shao, ... Science 352 (6290), 1232-1236, 2016	542	2016

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