Asymmetric Hydrogenation of Unsaturated Ureas with the BIPI Ligands CA Busacca, JC Lorenz, N Grinberg, N Haddad, H Lee, Z Li, M Liang, ... Organic letters 10 (2), 341-344, 2008 | 64 | 2008 |
Structure–activity study of bioisosteric trifluoromethyl and pentafluorosulfanyl indole inhibitors of the AAA ATPase p97 C Alverez, MR Arkin, SL Bulfer, R Colombo, M Kovaliov, MG LaPorte, ... ACS medicinal chemistry letters 6 (12), 1225-1230, 2015 | 59 | 2015 |
Evaluation of a novel calcium channel agonist for therapeutic potential in Lambert–Eaton myasthenic syndrome TB Tarr, W Malick, M Liang, G Valdomir, M Frasso, D Lacomis, SW Reddel, ... Journal of Neuroscience 33 (25), 10559-10567, 2013 | 55 | 2013 |
Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors MG LaPorte, Z Wang, R Colombo, A Garzan, VA Peshkov, M Liang, ... Bioorganic & medicinal chemistry letters 26 (15), 3581-3585, 2016 | 34 | 2016 |
Allosteric indole amide inhibitors of p97: identification of a novel probe of the ubiquitin pathway C Alverez, SL Bulfer, R Chakrasali, MS Chimenti, RJ Deshaies, N Green, ... ACS medicinal chemistry letters 7 (2), 182-187, 2016 | 33 | 2016 |
Complete reversal of Lambert–Eaton myasthenic syndrome synaptic impairment by the combined use of a K+ channel blocker and a Ca2+ channel agonist TB Tarr, D Lacomis, SW Reddel, M Liang, G Valdomir, M Frasso, P Wipf, ... The Journal of physiology 592 (16), 3687-3696, 2014 | 31 | 2014 |
Synthesis and biological evaluation of a selective N-and P/Q-type calcium channel agonist M Liang, TB Tarr, K Bravo-Altamirano, G Valdomir, G Rensch, L Swanson, ... ACS medicinal chemistry letters 3 (12), 985-990, 2012 | 27 | 2012 |
Synthesis and evaluation of esterified Hsp70 agonists in cellular models of protein aggregation and folding AN Chiang, M Liang, A Dominguez-Meijide, C Masaracchia, ... Bioorganic & medicinal chemistry 27 (1), 79-91, 2019 | 23 | 2019 |
Effectiveness of analogs of the GS-nitroxide, JP4-039, as total body irradiation mitigators MW Epperly, JR Sacher, T Krainz, X Zhang, P Wipf, M Liang, R Fisher, ... in vivo 31 (1), 39-43, 2017 | 22 | 2017 |
Lambert–Eaton myasthenic syndrome: mouse passive‐transfer model illuminates disease pathology and facilitates testing therapeutic leads SD Meriney, TB Tarr, KS Ojala, M Wu, Y Li, D Lacomis, A Garcia‐Ocaña, ... Annals of the New York Academy of Sciences 1412 (1), 73-81, 2018 | 19 | 2018 |
Synthesis and structure–activity relationships of small molecule inhibitors of the simian virus 40 T antigen oncoprotein, an anti-polyomaviral target AW Ireland, TA Gobillot, T Gupta, SP Seguin, M Liang, L Resnick, ... Bioorganic & medicinal chemistry 22 (22), 6490-6502, 2014 | 17 | 2014 |
New calcium channel agonists as potential therapeutics in Lambert–Eaton myasthenic syndrome and other neuromuscular diseases TB Tarr, G Valdomir, M Liang, P Wipf, SD Meriney Annals of the New York Academy of Sciences 1275 (1), 85-91, 2012 | 16 | 2012 |
New Cav2 calcium channel gating modifiers with agonist activity and therapeutic potential to treat neuromuscular disease M Wu, HV White, BA Boehm, CJ Meriney, K Kerrigan, M Frasso, M Liang, ... Neuropharmacology 131, 176-189, 2018 | 14 | 2018 |
Imidazolium compounds are active against all stages of Trypanosoma cruzi P Faral-Tello, M Liang, G Mahler, P Wipf, C Robello International journal of antimicrobial agents 43 (3), 262-268, 2014 | 13 | 2014 |
Synthesis of pyrrolo [1, 3] diazepines by a dipolar cycloaddition—retro-Mannich domino reaction M Liang, C Saiz, C Pizzo, P Wipf Tetrahedron letters 50 (49), 6810-6813, 2009 | 13 | 2009 |
A cross‐sectional study of ageing at the mouse neuromuscular junction and effects of an experimental therapeutic approach for dynapenia Y Li, M Patel, J Baroudi, M Wu, S Gatti, M Liang, P Wipf, Y Badawi, ... The Journal of Physiology 601 (18), 4135-4150, 2023 | 2 | 2023 |
Optimization of 1, 2, 4-triazole-based p97 inhibitors for the treatment of cancer MG LaPorte, C Alverez, A Chatterley, M Kovaliov, EJ Carder, ... ACS Medicinal Chemistry Letters 14 (7), 977-985, 2023 | 2 | 2023 |
Potentiation of neuromuscular transmission by a small molecule calcium channel gating modifier improves motor function in a severe spinal muscular atrophy mouse model KS Ojala, CJ Kaufhold, MR Davey, D Yang, M Liang, P Wipf, Y Badawi, ... Human Molecular Genetics 32 (11), 1901-1911, 2023 | 2 | 2023 |
Hdac inhibitors P Wipf, DM Huryn, MG Laporte, L Terrab, MJ Houghton, A Topacio, ... US Patent App. 18/039,941, 2024 | | 2024 |
Potentiation of neuromuscular transmission by a small molecule calcium channel gating modifier improves motor function in a severe spinal muscular atrophy mouse model (vol 32 … KS Ojala, CJ Kaufhold, MR Davey, D Yang, M Liang, P Wipf, Y Badawi, ... HUMAN MOLECULAR GENETICS 33 (1), 102-102, 2024 | | 2024 |